Nephrology

Widespread use of SLGT2 inhibitors (SGLT2i) is likely given recent recommendations for their use in chronic kidney disease and heart…

Salt restriction and hydrochlorothiazide (HCT) are known to increase the antihypertensive and antiproteinuric effects of…

Chronic kidney disease (CKD) has become a major public health problem, affecting over 9.1% of adults globally. Frailty is marked…

Intradialytic hypotension (IDH) is the most common complication of haemodialysis (HD). A purely nadir-based definition of IDH…

The automatic reporting of estimated glomerular filtration rate (eGFR) for all creatinine (Pcr) determination is mandatory, and the CKD-EPI…

The following selected highlights explore several fascinating abstracts that were presented at the 60th European Renal…

Chronic kidney disease (CKD) has been linked with an increased risk of cardiovascular events, especially in the dialysis population. In…

Indoxyl sulfate (IS) and p-Cresyl sulfate (PCS) are uraemic toxins originating from the breakdown of tryptophan and tyrosine/phenylalanine…

Chronic kidney disease (CKD) is a significant risk factor for preeclampsia (PE).1 However, the features of PE in this cohort of patients…

In the last few years, the effectiveness and role of drugs of the sodium-glucose co-transporter inhibitor group, or the so-called…

Thalassemia is a group of haemoglobinopathies characterised by the decrease or lack of β or α globin chain production haemoglobin (Hb)…

Gadolinium-based contrast agents are widely used for MRI. Although they may be considered well-tolerated at recommended dosing levels, recent evidence supports the deposition of free gadolinium in the tissues and its slow release into circulation, resulting in long-term toxicity, which is aggravated in renal patients.

The authors revisited the phenomenon of asymptomatic patients despite very low pulse oximetry readings, the so-called ‘sweet hypoxia’, ‘happy hypoxia’, or ‘silent hypoxaemia’.

Spontaneous renal artery dissection (SRAD) is a rare and often unrecognised clinical entity, which accounts for 1–2% of all arterial dissections. It can be the result of several underlying diseases, such as atherosclerosis, malignant hypertension, fibromuscular dysplasia, and connective tissue disorders.

The purpose of this study was to evaluate the effects of haemodialysis (HD) on B-cell subsets, in terms of untimely expression of immunosenescent phenotype.

Sickle cell disease (SCD) predisposes the patient to recurrent episodes of acute painful haemolytic crisis. Sickle cell nephropathy…

Serum cystatin C (cysC) is a protease inhibitor with a low molecular weight, which is produced by all nucleated cells at a constant rate…

Chronic kidney disease (CKD) is a growing problem in many parts of the world, with >700 million people affected.1 One of the main challenges in the…

Eosinophilic granulomatosis with polyangiitis (EGPA) is a small vessel vasculitis characterised by the presence of tissue eosinophilia…

Rituximab (RTX) is used worldwide for the treatment of glomerulonephritis (GN), including membranous glomerulopathy (MN), minimal change disease (MCD)…

In the early 1990s, clinicians in Central America and Sri Lanka noticed an upsurge of chronic kidney disease (CKD) in agricultural communities…

Despite clinical and lifestyle advantages of home haemodialysis (HHD) compared to in-centre hemodialysis,1 it remains underutilised in the province of…

Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic necrotising vasculitis affecting small to medium sized vessels, characteristically…

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare systemic autoimmune disease with a yearly incidence rate of around 20…