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miRNA Changes Track Functional Decline in Kidney Disease

September 2026

A study found that miRNA expression was associated with inflammation and reduced physical functional capacity in patients with end stage kidney disease, highlighting miR-16 and miR-206 as potential exploratory biomarkers.

miRNA Changes Track Functional Decline in Kidney Disease

A study found that miRNA expression was associated with inflammation and reduced physical functional capacity in patients with end stage kidney disease, highlighting miR-16 and miR-206 as potential exploratory biomarkers.

Biological age

Biological Age Predicts Mortality in Cardio-Kidney-Metabolic Syndrome

A nationwide cohort study found that biological age acceleration was associated with increased long-term mortality among adults with CKM syndrome stages 0–3.

Kidney Transplant Outcomes Remain Similar Across Regimens

A study of 112,952 kidney transplant recipients found comparable survival, graft loss and rejection outcomes across immunosuppressive regimens, with age not significantly altering these associations.

CKD Screening Recommended in Heart Disease: ESC 2026

New ESC guidelines call for routine CKD screening in patients with CVD, aiming to improve early diagnosis, optimise treatment, and reduce cardiovascular and kidney complications.

Finerenone is Linked to Increased Nephrolithiasis Risk

Real-world data linked finerenone with higher nephrolithiasis risk than other pharmacological therapies including spironolactone, SGLT2i, and ACEi/ARB in patients with CKD.

Kidney transcriptomic signatures

Kidney Transcriptomic Signatures Reflect Donor Diabetes Changes

A prospective study identified kidney transcriptomic signatures associated with donor diabetes and found that four transcripts attenuated after transplantation into non-diabetic recipients.

Renal Trauma is Managed Conservatively in 98% of Patients

Renal trauma was managed conservatively or with embolisation in 98% of 573 patients, including those with high-grade injuries.

Sex Differences Highlight Distinct Patterns in Glomerular Diseases

A nationwide biopsy analysis identified persistent sex differences in glomerular diseases, including variation in clinical presentation, age distribution and renal function.

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