Neurology

New 4D brain map unveils early warning signs and potential therapeutic targets for multiple sclerosis, offering hope for improved treatments.

Brain haemorrhages double dementia risk, urging regular cognitive screening for affected patients. New research highlights critical clinical implications.

A clinical trial finds tetramethylpyrazine nitrone safe for ALS, with potential benefits in grip strength for younger patients.

AI-powered MELD Graph detects 64% of epilepsy-causing lesions missed by radiologists, enhancing FCD diagnosis and surgical planning.

New research suggests both low and high vitamin B12 levels impact brain health in older adults, challenging current recommendations.

Teleneurorehabilitation safely improves Parkinson’s symptoms and quality of life, offering a viable alternative to in-person therapy.

Explore how genetic and phenotypic features of psychosis in epilepsy can guide precision medicine.

Pridopidine did not slow ALS progression in a 24-week trial. Findings highlight the need for continued research and alternative therapies.

New research finds adults with depression develop physical illnesses 30% faster. Integrated care approaches are urgently needed.

Stroke survivors with high genetic risk for type 2 diabetes face poorer blood sugar control, new study reveals.

High-frequency oscillations predict seizure risk in Alzheimer’s. Levetiracetam reduces them in epileptic patients but increases them in non-epileptic cases.

Replacing regular salt with a reduced-sodium, added-potassium substitute significantly lowered recurrent stroke and mortality risk in stroke patients.

Delayed REM sleep may indicate early Alzheimer’s, with longer REM latency linked to increased toxic protein levels and reduced neuroprotective factors.

Microplastics are accumulating in human brains at increasing levels, with potential links to dementia and other neurological concerns.

A deep-learning algorithm predicts Parkinson’s disease using medical claims and prescriptions, improving early detection and clinical screening.

A recent ARTESiA trial analysis suggests apixaban may reduce stroke risk in patients with subclinical atrial fibrillation and a history of stroke

Intranasal oxytocin every third day modestly reduced apathy in frontotemporal dementia patients, offering a potential treatment approach.

Butylphthalide reduces cognitive decline in stroke survivors over 12 months, offering promising neuroprotection for post-stroke care.

Ophthalmic complications linked to semaglutide and tirzepatide raise concerns for diabetic patients on these medications.

Researchers have identified a cortical biomarker signature that accurately predicts individual pain sensitivity, paving the way for personalised pain management.

New research shows propranolol reduces Parkinson’s tremor and motor cortex activity, offering a potential treatment option.

Heavy alcohol consumption, particularly binge drinking, is a significant risk factor for cryptogenic ischaemic stroke in young men.

Hearing loss linked to a 57% higher Parkinson’s risk per 10-decibel decline, suggests new Lancaster University study.

Data review suggests antibiotics, vaccines, and anti-inflammatory drugs reduce dementia risk, advancing drug repurposing opportunities.

Processed red meat raises dementia risk by 13%, but replacing it with fish or nuts reduces risk by 20%.

Pupillometry predicts neurological deterioration in MCA stroke, offering insights for early intervention up to 12 hours prior.

Lecanemab targets toxic amyloid-β protofibrils in Alzheimer’s disease, correlating with reduced neurodegeneration and cognitive decline.

Mood alterations linked to sporadic Creutzfeldt-Jakob disease: Study finds rising SSRI prescriptions years before symptom onset.

TAK-071 enhances cognition in Parkinson’s disease but doesn’t reduce gait variability, phase 2 trial results reveal.

New biomarker links glymphatic dysfunction to vascular dementia, revealing pathways for prevention and treatment strategies.

Hypertensive pregnancy disorders increase the risk of migraines, epilepsy, and more neurological issues up to 15 years later.

Ketamine offers new hope for Parkinson’s dyskinesia by restoring motor cortex control and promoting long-term neural repair.

Metabolic, sensory, and ocular symptoms may predict paediatric MS up to five years before diagnosis, study finds.

Study links maternal tobacco use in pregnancy to long-term brain changes, urging preventive action for improved child health.

Groundbreaking study uses EEG and AI to diagnose Parkinson’s disease with near-perfect accuracy through emotional response analysis.

Chronic gut infections from cytomegalovirus may contribute to Alzheimer’s, opening doors to antiviral treatment possibilities.

Antibody NG101 improves motor recovery in incomplete spinal cord injury, offering hope for rehabilitation breakthroughs.

Vagus nerve stimulation improves sleep quality and mental health in chronic insomnia.

A new biological definition of Parkinson’s and dementia with Lewy bodies proposes an integrated staging system for research.

Plasma p-tau217 immunoassay shows high diagnostic accuracy for Alzheimer’s disease pathology, aiding early detection.

The study supports a unified set of diagnostic criteria for multiple sclerosis, improving accuracy in diagnosing progressive disease forms.

Machine learning models using MRI improve neurodevelopmental predictions in neonates with hypoxic-ischemic encephalopathy.

Study links high dementia risk in ex-soccer players to head impacts, not general health and lifestyle factors.

Discontinuing first-line therapy in stable multiple sclerosis can trigger inflammation recurrence in 20% of patients.

Key EEG, MRI, and clinical findings predict outcomes in neonates with HIE treated with hypothermia, aiding prognosis.

Imaging reveals how skull regions mediate brain-periphery immune crosstalk in depression, uncovering new therapeutic targets.

Cyclophosphamide offers rapid remission and long-term benefits in high-risk myasthenia gravis, reducing corticosteroid reliance and injectable therapies.

Antipsychotics may worsen behavioral symptoms in long-term care residents, according to a large Canadian study. Researchers found a significant association between antipsychotic use and behavioral deterioration, urging caution in prescribing these medications.

Study finds SARS-CoV-2 spike protein persists in brain tissues for years, with vaccines reducing this accumulation by 50%.

Study links Beta blocker therapy to delayed motor onset and slower progression in Huntington disease, suggesting therapeutic benefits.

Low-field 0.23-T MRI with a novel sequence achieves 100% accuracy in stroke diagnosis within 24 hours of onset.

Discover how Parkinson’s disease-related sleep disruptions link to subthalamic nucleus brain activity and potential new treatments.

Prenatal maternal immune activity affects offspring memory circuitry, with lifelong, sex-specific impacts on brain health and cognition.

A new study shows how amyloid and tau-PET scans can help track Alzheimer’s progression in adults with Down syndrome.

Wearable TENS therapy significantly reduces pain, fatigue, and mobility issues in long COVID, showing promise for symptom management.

High-dose noncancer opioid use linked to dementia risk in Danish study, emphasising need for cautious pain management strategies.

Middle meningeal artery embolisation lowers adverse events but shows no clear advantage in preventing subdural hematoma recurrence.

Spinal cord stimulation outperforms conventional medical management for chronic pain relief, improving pain intensity, quality of life, and disability at six months.

Discover how menopausal hormone therapy impacts brain health based on age, duration, and surgical history. Personalised approaches to MHT could improve women’s neurological outcomes.

This new research sheds light on shared and subtype-specific genetic variations and points to potential targets

Dual brain stimulation therapies significantly outperformed standalone treatments in reducing depression severity, offering new hope for patients with major depressive disorder.

Patients with traumatic brain injury (TBI) and hypotension face doubled mortality odds, highlighting the need for precise blood pressure management in clinical practice.

Asthma may impact children’s memory and cognitive function, particularly when it begins early, according to new research on childhood asthma’s cognitive effects.

Research shows that frailty increases 4 to 9 years before dementia, marking it as an early indicator. Monitoring frailty could help identify high-risk individuals, supporting preventive dementia strategies.

Recent research has revealed that alcohol use disorder and Alzheimer’s disease share significant patterns of gene dysregulation.

A recent 18-month study observed that lower blood sugar levels were associated with younger brain age, particularly in regions linked to memory and sensory processing.

A randomised clinical trial found that lowering levels of iron in the brain using deferiprone may accelerate cognitive decline in patients with early-stage Alzheimer’s disease

Childhood attention issues, when combined with genetic predispositions, significantly increase the likelihood of experiencing psychotic-like symptoms in adolescence

Research has determined an association between prenatal cannabis exposure and increased aggression, and poorer cognitive function in children aged five.

The British Sleep Society (BSS) recommends that the UK government abolish the twice-yearly clock changes, citing the negative impact of these adjustments on sleep and circadian health.

Compared to other anti-diabetic drugs, semaglutide, also known as Ozempic, may lower the risk of Alzheimer’s disease in people with Type 2 diabetes (T2D).

Individuals who received multiple courses of penicillin antibiotics had a 15% lower risk of developing Parkinson’s disease (PD), while those who used antifungal medications had a 16% higher risk.