Oncology - European Medical Journal

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EMJ Oncology 8.1 2020 Feature Image
2 Mins
5 Nov 2020

Safety of Fertility Treatments in Breast Cancer Survivors

Quality of life for cancer survivors has become a priority in cancer care and research. Almost 50% of the young patients who have survived breast cancer (BC) have expressed their desire to become pregnant…
2 Mins
5 Nov 2020

PEAR Study: UK Experience of the Management of Pregnancy-Associated brEast cAnceR: A National Retrospective Review of Practice

Breast cancer is the leading cause of death in females aged 35–54 years and 15% of breast cancers first present in females of reproductive age…
1 Mins
5 Nov 2020

Chemotherapy Options in Recurrent Glioblastoma

Most patients with glioblastoma will develop a recurrence despite initial aggressive therapy with maximum surgical resection and postoperative chemoradiation…
1 Mins
12 Nov 2019

A Novel Affinity-Enhanced NY-ESO-1-Targeting TCR-Redirected T cell Transfer Exhibiting Early-Onset Cytokine Release Syndrome and Subsequent Tumour Responses in Synovial Sarcoma Patients

Adoptive transfer of T cell receptor (TCR)-redirected T cells has been reported to exhibit efficacy in some patients with melanoma and sarcoma…
2 Mins
12 Nov 2019

A Phase II Study of Pazopanib as Front-Line Therapy in Patients with Nonresectable or Metastatic Soft Tissue Sarcomas Who are Not Candidates for Chemotherapy

Patients with metastatic soft tissue sarcoma (STS) have a poor prognosis with a median survival of 12–14 months.1 First-line therapy consists…
2 Mins
12 Nov 2019

The Mutational Signature of Spontaneously Developing Tumours in MLH1-/- Mice - Potential Consequences for Immunotherapeutic Approaches

Mismatch repair-deficient (MMR-D) tumours exemplify the prototypic hypermutator phenotype. Owing to the high mutation rates, many neo-antigens…
1 Mins
12 Nov 2019

The 2016-2019 ImmunoTOX Assessment Board Report: Results from a Descriptive Real-Life Study of a Collaborative Management of Immune-Related Adverse Events Induced by Immune Checkpoint Inhibitors

Although immunotherapy is better tolerated globally than chemotherapy, immune checkpoint inhibitors may be associated with immune-related…
2 Mins
12 Nov 2019

Measuring the Cancer Burden in Europe: the European Cancer Information System (ECIS)

Cancer is the second leading cause of mortality in European Union (EU) Member States,1 with more than 1.4 million deaths…
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