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1 Mins
12 Nov 2019

Phase I Combination Dose-Finding and Phase II Expansion Cohorts of Lenvatinib with Etoposide and Ifosfamide in Patients Aged 2 to ≤25 Years with Relapsed or Refractory Osteosarcoma

Osteosarcoma is the most common primary bone tumour in adolescents and young adults, with no survival improvement in the last few decades…
2 Mins
6 Dec 2018

First In-Human Study with GSK3359609, an Inducible T cell Costimulator Receptor Agonist in Patients with Advanced, Solid Tumours: Preliminary Results from INDUCE-1

Inducible T cell costimulator (ICOS), a member of the CD28/B7 receptor superfamily, is expressed on T cells after T cell receptor engagement with cognate…
1 Mins
6 Dec 2018

Preliminary Safety, Efficacy, and Pharmacokinetic and Pharmacodynamic Characterisation from GARNET, a Phase I Clinical Trial of the Anti-PD-1 Monoclonal Antibody TSR-042 in Patients with Recurrent or Advanced Microsatellite Instability-High Endometrial Cancer

At the European Society for Medical Oncology (ESMO) 2018 Congress, data from the ongoing Phase I clinical trial of the anti-programmed death…
1 Mins
6 Dec 2018

Patient Reports of Mouth Symptoms after Radiotherapy Treatment for Head and Neck Cancer: An International Survey

People with head and neck cancer frequently have symptoms that are caused by their disease or by their treatments, which may significantly impact on…
1 Mins
6 Dec 2018

New Immunotherapy Approaches for The Treatment of Cancer: Reported at the European Society for Medical Oncology Congress 2018

Immunotherapy is currently a pillar in the treatment of cancer, in addition to surgery, radiotherapy, chemotherapy, and molecular-targeted therapies.
2 Mins
6 Dec 2018

Major Determinants of Delayed Access to Innovative Medicines for Metastatic Melanoma: The Results of the Melanoma World Society (MWS) and European Association of Dermato-Oncology (EADO) Survey

At the 2018 European Society for Medical Oncology (ESMO) Congress in Munich, Germany, the Melanoma World Society (MWS) and European Association of…
1 Mins
24 Oct 2017

Dexamethasone Contributes to the Side Effects in Glioblastoma Treatment

Glioblastoma (GBM) is the most common and malignant primary brain tumour and is characterised by the active invasion of tumour cells into surrounding…
2 Mins
24 Oct 2017

Experience in Managing Patients with Carcinoid Syndrome from A European Neuroendocrine Tumour Society Centre Of Excellence

Carcinoid syndrome is a combination of signs and symptoms, such as skin flushing, diarrhoea, bronchospasm, and fibrotic valvulopathy, resulting from…
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