Oncology

Radioresistance is known to create complications in the treatment of cancer.1 Radiation-induced altered adaptive responses by tumour cells or tissues are considered to be primary reasons behind the failure of radiotherapy.2 Acquirement of radioresistance followed by treatment failure and locoregional recurrence is a multifaceted process. Emerging data have suggested various molecular biomarkers necessitate radioresistance in cancer.

Soft tissue sarcomas (STS) are a group of rare mesenchymal tumours that can arise in patients of any age and in a variety of anatomic sites. It is estimated that STS make up 1% of all adult malignancies and that their incidence is on the rise. The lower limb is the most commonly affected site, with approximately 28% of STS arising there. With at least 50 different histologic subtypes, STS are considered highly heterogenous in terms of their histopathology and their tendency to metastasise. Undifferentiated pleomorphic sarcomas and liposarcomas are the most common histopathologic subtypes in adult patients.

Ovarian cancer is the seventh most common cancer in females,1-3 and the most lethal gynaecologic malignancy globally because of its vague…

Current diagnostic approaches in CCA are inadequate, without additional histological confirmation and, with no efficient screening…

Venous thromboembolism (VTE) is one of the main reasons for morbidity and mortality among patients with malignancies. In addition, in this…

EMJ conducted interviews with two key opinion leaders and specialists in the prevention and treatment of cancer-related venous…

This article discusses the results published in 2020 and early 2021 from key clinical trials of PARP inhibitors in patients with advanced ovarian cancer in terms of long-term efficacy and survival rates.

Dr Prat explained that there are three main variables that should be considered when determining the risk of recurrence for…