Respiratory

Younger adults with early-onset lung cancer face poorer survival linked to late diagnosis, income, and access to care, highlighting urgent equity needs.

A Taiwanese study identifies lncZPBP2-3 as a pollution-responsive gene variant that heightens asthma risk with long-term PM2.5 exposure.

The MUSIC trial shows high-dose fluticasone elevates sputum bacterial load in severe COPD, without affecting upper airway microbiome, and ICS withdrawal can trigger exacerbations.

The ERS has released evidence-based guidelines for adult bronchiectasis care, offering structured recommendations on airway clearance, macrolides, and inhaled antibiotics.

Hypnosis can enhance comfort and clinical efficacy of non-invasive ventilation masks, reducing sedation needs and distress in acute respiratory failure patients.

New Mendelian randomisation study confirms a causal link between gut microbiota and childhood asthma.

A phase 3 trial found that retifanlimab plus chemotherapy significantly improved survival in patients with metastatic NSCLC, with a safety profile consistent with other PD-1 inhibitors.

New ERS 2025 research links paternal smoking in puberty with accelerated biological ageing in offspring, reinforcing evidence of intergenerational tobacco harms.