Respiratory

Nebuliser use in COPD is most common in severe disease with frequent exacerbations, high symptoms, and reduced lung function.

New cohort data show higher air pollution exposure is linked to more respiratory infections and wheezing in infants during the first year of life.

A new inhaled therapy targeting lung inflammation shows promise in reducing damage and improving recovery after severe respiratory infections.

European data identify distinct multimorbidity patterns in severe asthma, linking comorbid clusters to outcomes, steroid use, and disease control.

SPECT lung scans show low clot risk at three months, suggesting a potential alternative to CT in pulmonary embolism diagnosis.

A new hybrid AI model improves lung cancer detection on CT scans, achieving over 96% accuracy for early tumour identification.

Children with sleep breathing disorders score lower across cognitive domains, highlighting risks for learning and memory deficits, meta-analysis finds.

Rapid testing identifies acute respiratory distress syndrome subtypes linked to mortality, supporting precision medicine in critical care.

Type D personality was linked to lower adherence and more side-effects in bilevel positive airway pressure therapy for sleep apnoea patients.

Study finds indoor air pollution peaks in respiratory patients are driven by daily activities like cooking, often exceeding WHO guidelines.

Large study shows reducing dampness through home upgrades improves respiratory health, especially in children, supporting housing as a key public health intervention.

New research explores COVID-19 outcomes in cystic fibrosis transplant recipients, highlighting lung function as a potential factor linked to disease severity.

Survival rates in mice increased from 0% to 62.5%, alongside marked reductions in inflammation, alveolitis, and extracellular matrix deposition.

Severe COVID-19 may raise lung cancer risk by creating a tumour-promoting lung environment after viral pneumonia, new research suggests.

High-frequency oscillatory ventilation (HFOV) reduced bronchopulmonary dysplasia in preterm infants with neonatal respiratory distress.

A new human lung ageing atlas reveals cell-specific changes, mutation buildup, and declining lung repair capacity linked to ageing.

Distinct COPD phenotypes show major differences in severity and mortality, with worse outcomes linked to income, race, rural living, and smoking.

Pipe and cigar smoking is linked to faster lung function decline and higher mortality, even among people who have never smoked cigarettes.

Adhering to Life’s Essential 8 may lower chronic respiratory disease risk and support long-term lung health, reports a large population-based study.

High adherence to the Mediterranean diet was linked to a significantly lower risk of adult-onset asthma in a large Spanish cohort study.

Obstructive sleep apnoea may affect 1 in 5 adults in the UK and USA, costing billions in lost productivity, but can be offset by effective treatment.

Indoor asthma triggers such as smoking, poor ventilation, and mould are strongly linked to worse symptoms and daily limitations, a large study finds.

A European study finds hospitalisations and insufficient growth reduce health-related quality of life in childhood interstitial lung disease.

UCLA researchers use lipid nanoparticles to insert full CFTR gene into airway cells, restoring function and opening new avenues for CF therapy.

Major study finds chronic exposure to wildfire smoke PM2.5 linked to 24,000 USA deaths per year, with no safe threshold and strong neurological impacts.

Lung cancer in never smokers is rising, with distinct risks and biology, highlighting the need for tailored screening, prevention, and treatment.

A new study finds adults consuming more sugary drinks have higher odds of COPD, highlighting links between diet, lung health, and overall wellbeing.

New registry data show bronchiectasis affects multiple alpha-1 antitrypsin deficiency genotypes, not just Pi*ZZ, with key implications for screening.

Global research shows asthma microbiome and airway inflammation differ by region, but neutrophilic asthma shows consistent bacterial patterns.

Residential wood burning contributes substantially to winter PM2.5 pollution in the USA, linked to thousands of premature deaths.

A large meta-analysis identifies patient, clinical, and biochemical factors linked to early mortality in septic shock, helping clinicians stratify risk.

Nationwide cohort data suggest vitamin K antagonists are linked to a lower 1-year risk of severe COPD exacerbation or death compared with DOACs.

Study of over 600,000 people finds genetic differences influencing pneumonia risk across age, immunity, and smoking behaviour.

Large genetic study links telomere-related polygenic risk to distinct idiopathic pulmonary fibrosis subgroups, improving disease prediction.

A major trial finds the beta blocker bisoprolol neither improves nor worsens outcomes in people with COPD, despite their high cardiovascular risk.

UK Biobank study links very low vitamin D levels with higher risk of hospital admission for respiratory tract infections across ethnic groups.

Sphingolipid-to-steroid ratios in blood accurately predict asthma attacks years in advance, offering a new precision medicine tool for asthma care.

Teens with obesity using GLP-1RAs experienced fewer asthma exacerbations, emergency visits, and steroid prescriptions compared with nonpharmacological weight management.

Expanded school tobacco prevention in California schools was linked to lower adolescent tobacco use in a large, state-representative survey.

High cannabis use is associated with worse lung function, respiratory symptoms, and airway immune changes, highlighting potential clinical risks.

Meta-analysis links prior tuberculosis and chronic bronchitis to higher lung cancer risk in never-smokers, with implications for clinical risk assessment.

Therapist-guided internet CBT safely lowers asthma-related anxiety and boosts quality of life, control, and behaviour in adults with asthma.

A 1000 ng/mL D-dimer threshold safely rules out pulmonary embolism in low-likelihood patients, reducing unnecessary chest imaging in emergency care.

Combining a host biomarker with large language model analysis improves lower respiratory tract infection diagnosis in ICU patients, reducing uncertainty.

NHS opt-out tobacco dependency services boost quit attempts in deprived populations, but success lags, highlighting opportunities to reduce inequalities.

Medication-induced deep sedation in ICU patients is linked to loss of independence; lighter sedation and mobility improve outcomes, study finds.

A novel iPSC-derived lung-on-chip model mimics human alveolar tissue, revealing macrophage-driven tuberculosis responses.

Rare inherited genetic variants linked to mucin glycosylation and DNA repair significantly increase familial lung cancer risk, offering new targets for early detection.