Respiratory

A randomised trial finds that blowing a conch shell reduces daytime sleepiness, improves sleep quality, and lowers apnoea severity in people with obstructive sleep apnoea.

ERS/EULAR guidelines provide detailed recommendations for diagnosing, monitoring, and treating connective tissue disease-related interstitial lung disease, tailored to disease type and risk profile.

Study finds trained dogs detect lung cancer with 78% accuracy from breath samples versus 42% from saliva.

Hospital asthma exacerbations rise in later pregnancy, with reduced inhaled corticosteroid use a key modifiable risk factor, UK data show.

By 2050, nearly half of US adults aged 30–69 will have obstructive sleep apnoea, with cases rising to 76.6 million and the steepest growth seen in women.

Central tumour location linked to worse survival in lung cancer, suggesting need for closer post-operation monitoring.

Understand how an AI model uses chest CT scans to diagnose COPD with 95% accuracy.

A nearly three-decade study has revealed a significant rise in triazole-resistant Aspergillus fumigatus, a fungus responsible for invasive aspergillosis…

Study shows diets high in saturated fatty acids drive lung inflammation and worsen airway disease, similarly to obesity-related asthma.

Airway bacteria like Streptococcus oralis may boost natural immune defences, helping protect against pneumonia and viral infections, new research suggests.

COVID-19 infection raises risks of asthma, rhinitis, and sinusitis, while vaccination reduces respiratory type-2 inflammatory disease incidence.

Respiratory viruses such as influenza and SARS-CoV-2 can awaken dormant breast cancer cells, driving metastasis and raising mortality risk in cancer survivors, new research finds.

A registry-based analysis using Bayesian modelling has mapped the pathways linking biomarkers, lung function, and comorbidities to severe asthma exacerbation risk.

A UK registry study shows asthma biologics improve outcomes across BMI groups, but obese patients remain more likely to have uncontrolled disease.

A large pooled analysis shows that kidney problems are common in PAH and CTEPH, worsen survival, and see only minor improvement with current pulmonary hypertension therapies.

Meta-analysis confirms low income is linked to increased asthma exacerbations, especially in children, highlighting income inequality as a key risk factor.

A global trial finds a shorter all-oral regimen for pre-XDR tuberculosis fails to match the efficacy of standard care, with poorer results in those with extensive disease.

A new Europe-wide analysis reveals that RSV hospitalisations in older adults are far more common than previously reported, highlighting the importance of updated data in vaccine policy planning.

A new AI model shows promise in predicting survival in patients with fibrotic lung disease, offering more precise prognosis than standard tests and imaging methods.

Real-world study finds benralizumab leads to long-term clinical remission in up to 39% of patients with severe eosinophilic asthma.

Long-term exposure to fine particulate matter and nitrogen dioxide is linked to increased dementia risk, according to a major new meta-analysis involving over 24 million people.

A long-term study finds sotatercept continues to improve outcomes in patients with pulmonary arterial hypertension, with manageable safety risks.

A mobile asthma self-management tool improved symptoms in adults with uncontrolled asthma, but its effectiveness varied across racial groups.

Scientists uncover shared genetic signals between chronic dry cough and ACE inhibitor-induced cough, pointing to neurological pathways as potential targets.

Tozorakimab shows potential benefit in patients with COPD with frequent exacerbations, despite primary endpoint not being met in overall population.

Macrophages in COPD lungs show elevated carbon loads, larger cell size, and enhanced inflammation, highlighting a potential driver of disease progression.

Paediatric-onset bronchiectasis leads to more severe disease than adult-onset, highlighting need for early, tailored care.

MiDAS, a new clinical tool, predicts poor outcomes in difficult asthma by scoring multimorbidity burden, highlighting the need for whole-patient care.

A post hoc analysis confirms dupilumab reduces key inflammatory biomarkers and COPD exacerbations, with highest benefit in patients with raised eosinophils and FeNO.

A major European study finds that exposure to multiple urban environmental factors, including air pollution and lack of green space, is significantly linked to asthma risk from childhood to adulthood.

A 14-gene test helps identify patients with early-stage non-small-cell lung cancer who benefit from chemotherapy, significantly improving 24-month disease-free survival.

The serotonin receptor gene HTR1F was linked to increased risk of sleep apnoea in non-obese adults.

CHEST guideline updates support minimally invasive resection and targeted therapy to enhance survival in Stage I–II NSCLC.

Dupilumab was associated with increased lymphoma risk but lower overall mortality in a large asthma cohort study.

A new international trial has investigated the safety and efficacy of tailoring antibiotic treatment for cystic fibrosis exacerbations based on sputum microbiome analysis.

A genome-wide association study reveals four novel loci linked to primary spontaneous pneumothorax, identifying CBX7-mediated matrix dysregulation as a key pathogenic mechanism.

Air pollution and poverty accelerate ageing and worsen survival in fibrotic lung disease patients, new international epigenetic study reveals.

New global registry study reveals stark regional differences in diagnosis, treatment, and care quality for children with bronchiectasis.

New research links TP53, BRCA2, and ALKBH2 mutations to early-onset lung cancer in Asian women who have never smoked.

Early evidence shows that nirsevimab substantially reduced emergency bronchiolitis cases and hospital admissions in infants under 6 months.

A large Phase III trial has found that onradivir, a novel PB2 polymerase inhibitor, significantly shortens recovery time in adults with uncomplicated influenza A.

A structured parenting programme based on acceptance and commitment therapy has shown clinical benefits in managing asthma and ADHD symptoms in children.

New findings support the integration of PET/CT prior to biopsy in patients with intermediate-to-high-risk lung nodules.

A major international trial has assessed whether nasal high-flow oxygen improves outcomes during emergency paediatric intubation.

Next-generation metagenomic sequencing has uncovered key differences in bronchiectasis pathogens and resistance genes across Europe.

Machine learning models using data from digital inhalers can successfully predict COPD exacerbations up to 5 days in advance.

New research suggests that early impairment in mucosal IgA immunity may contribute to the later development of bronchiolitis obliterans syndrome in lung transplant recipients.

Gait parameters in people with COPD progressively worsen with disease severity and differ significantly from healthy older adults.

New research shows lung function peaks earlier in life and declines steadily without plateau, challenging prior assumptions.

A once-daily oral therapy targeting neutrophilic inflammation has shown promise in reducing exacerbations in patients with bronchiectasis.

Including imaging and symptom-based data in COPD diagnosis captures patients with high-risk disease who would otherwise be overlooked by spirometry alone.

Repeated exposure to antibiotics during the perinatal period in very low birth weight preterm infants is associated with impaired lung function by early school age.

A new study identifies airway eosinophilia as a distinct, corticosteroid-responsive subtype of COPD, marked by heightened type 2 inflammation and gene expression changes.

A new Phase III trial has strengthened the evidence supporting cytisinicline as an effective and well-tolerated medication for smoking cessation.

Rare genetic variants and common polygenic risk scores independently influence survival in idiopathic pulmonary fibrosis.

Discover how HSK31858 could transform bronchiectasis treatment by reducing flare-ups – read more about the latest trial results.

New data reveal that acute pulmonary embolism, though rare in children and adolescents, carries a significant risk of death.

Smoking may reduce the risk of developing ulcerative colitis and alleviate disease severity in existing cases.

Statistical analysis shows combined breathing and stretching exercises significantly improve respiratory function and exercise capacity in COPD patients.

Youth using varenicline with brief behavioral support were far more likely to quit vaping than those given placebo or usual care, a new randomized trial finds.

A new study supports the clinical utility of human nasal epithelial cultures as predictive biomarkers for cystic fibrosis CFTR modulator therapy.

Blood eosinophil count and fractional exhaled nitric oxide significantly enhance prognostic assessment of asthma attack risk.

A single dose of the RSVPreF3 OA vaccine offers strong protection against RSV-related lower respiratory tract disease in older adults across three seasons.

Explore how vaping during pregnancy affects maternal health and birth outcomes.

A new 96-week study confirms the long-term safety and sustained efficacy of elexacaftor/tezacaftor/ivacaftor in children with cystic fibrosis aged 6–11 years.

Inpatient pulmonary rehabilitation significantly enhances functional independence in patients with chronic lung disease and extends survival.

A study analysing trends in mortality from occupational chronic respiratory diseases caused by industrial pollutants highlights both progress and ongoing challenges.

Early exposure to ambient ozone in the first 2 years of life is associated with an increased risk of asthma and wheeze in early childhood.

A novel therapeutic vaccine, PRGN-2012, has shown promising results in treating recurrent respiratory papillomatosis.

Obstructive sleep apnoea may increase the risk of developing Parkinson’s, but early treatment with continuous positive airway pressure therapy mitigates this risk.

IL-33 inhibition with tozorakimab may offer clinical benefits in patients with COPD at high risk of exacerbations.

Young adults who use e-cigarettes may experience changes in lung ventilation distribution, potentially indicating early small airway impairment.

Children with above-average BMI trajectories are at increased risk of developing chronic obstructive pulmonary disease later in life.

Molecular residual disease detection may help identify patients with EGFR-mutated NSCLC who could benefit from prolonged adjuvant osimertinib

A new study highlights the significant impact of time of day and season on bronchodilator responsiveness.

A multicentre cohort study found that adherence to annual lung cancer screening declines over time, with lower adherence linked to reduced lung cancer detection rates.

New data confirm that positive airway pressure therapy is associated with a significant reduction in all-cause and cardiovascular mortality in patients with obstructive sleep apnoea.

New research finds that SGLT-2is and GLP-1RAs are associated with a lower risk of COPD exacerbations in patients with Type 2 diabetes and active COPD.

New research has identified a potential causal relationship between lipid metabolism and chronic obstructive pulmonary disease.

Adjuvant corticosteroid therapy reduces 30-day mortality in hospitalised patients with community-acquired pneumonia, but its benefits depend on baseline inflammation levels.

Gut microbiota composition may influence the efficacy and safety of chemo-immunotherapy in advanced non-small cell lung cancer.

A Phase IV trial has demonstrated that dupilumab significantly reduces airway inflammation in patients with uncontrolled, moderate-to-severe type 2 asthma.

Interim findings from the ongoing SOTERIA study suggest that sotatercept provides a favourable long-term safety and efficacy profile for adults with pulmonary arterial hypertension.

A new study assessed asthma risk in children who received antibiotics in the first week of life solely due to maternal indications, eliminating infection-related bias.

A large-scale study suggests that pirfenidone use in patients with idiopathic pulmonary fibrosis may be linked to a lower incidence of lung cancer.

Individuals with impaired lung function trajectories experience a higher burden of respiratory symptoms, including wheeze and phlegm.

The UK IPF Registry has provided new insights into the evolving landscape of idiopathic pulmonary fibrosis management, showing significant shifts in diagnosis and treatment approaches over the last decade.

Lung cancer screening presents a crucial opportunity to address tobacco dependence, as participation is associated with increased motivation to quit smoking.

A nationwide study from South Korea has found a concerning link between obstructive sleep apnea and suicidal behaviors.

Adding genetic risk scores to traditional case-finding methods enhances the detection of undiagnosed COPD, improving early diagnosis and intervention.

A large, multicentre study has demonstrated that robotic-assisted bronchoscopy is both safe and effective for diagnosing small and peripheral lung lesions.

A Phase III trial has shown that rezivertinib offers superior progression-free survival compared to gefitinib as a first-line treatment in EGFR-mutated locally advanced or metastatic non-small-cell lung cancer.

Adults who began smoking before the age of 15 have a significantly higher risk of COPD than those who started later, even when adjusting for smoking history and second-hand smoke exposure.

Extreme temperatures significantly increase morbidity and mortality risks for patients with chronic obstructive pulmonary disease.

A new study across five European countries highlights the impact of RSV on clinical outcomes, healthcare utilisation, and family life.

A large-scale study has revealed a significant association between long-term air pollution exposure and hospital admissions for acute lower respiratory infections in adults.

A new global analysis of lung cancer incidence has uncovered significant geographical and temporal variations in histological subtypes.

New research suggests that elevated circulating cAMP levels could serve as a potential biomarker for asthma.

Vitamin D deficiency is strongly associated with an increased risk of severe acute exacerbations in patients with chronic obstructive pulmonary disease.

New research reveals shifting patterns in lung cancer mortality, with declining smoking rates offset by rising deaths linked to air pollution.

A new qualitative study conducted in France highlights the multiple obstacles patients face before receiving a chronic obstructive pulmonary disease diagnosis.

A systematic review of 33 randomised controlled trials has found that conventional treatments for allergic rhinitis may also improve asthma outcomes in patients with both conditions.

A recent study has uncovered a new connection between genetic risk factors for idiopathic pulmonary fibrosis and the development of post-COVID-19 lung abnormalities.

Xpert MTB/RIF Ultra is able to enhance tuberculosis diagnosis and stratify transmission risk, offering a powerful tool for clinicians.

With traditional bronchial provocation tests often inaccessible in clinical settings, this predictive nomogram offers a practical alternative to assist clinicians.

The Prospector calculator reduces antibiotic use by nearly half in COPD exacerbations, showing promise for safer and more effective patient care.

A high blood NMLR is linked to increased 5-year mortality in COPD patients, highlighting its role as a key prognostic tool.

Home high-flow therapy improves recovery for COPD patients after severe exacerbations, showing potential for better symptom control and reduced readmissions.

A recent outbreak in India identified new hMPV strains, A2.2.1 and A2.2.2, highlighting the evolving threat of paediatric respiratory infections.

Combined valve implantation in the right upper and middle lobes shows promise for severe emphysema, with significant benefits for heterogeneous cases.

1 in 28 people globally will develop lung cancer, with men and wealthy nations at greatest risk, highlighting urgent healthcare disparities.

Changes in muscle-to-fat ratio affect lung function and airflow obstruction, highlighting the importance of body composition in respiratory health.

Rising blood eosinophil counts and high sputum IL-8 levels predict accelerated lung function decline in asthma, highlighting key biomarkers for monitoring.

LCI detects lung function improvements in cystic fibrosis patients on ETI therapy, even when FEV1 changes are minimal, highlighting its clinical value.

Lung cancer deaths among CLRD patients have declined, but older adults, rural areas, and White men remain disproportionately affected.

GLI spirometry criteria reduce COPD misclassification in older smokers, ensuring accurate diagnosis and preventing unnecessary treatments.

New research highlights the predictive power of gut microbiome profiles during acute COVID-19 infection in identifying individuals at risk for Long COVID.

A UK Biobank study links low birth weight to a 21% higher risk of developing COPD later in life. Findings highlight the importance of prenatal care and maternal health in reducing long-term respiratory risks.

A study reveals a strong link between primary ciliary dyskinesia and asthma in children.

Prenatal exposure to common phenols, including butylparaben, has been linked to an increased risk of asthma in children, particularly among boys, according to a large-scale study from Japan.

Living in disadvantaged neighbourhoods worsens lung function and raises mortality risk for idiopathic pulmonary fibrosis patients, especially those with milder disease, according to a new study.

New research highlights how patient-reported asthma symptoms can reveal underlying disease mechanisms, paving the way for personalised treatments.

Doctors should monitor thoracic trauma patients with lateral or posterior rib fractures, displacement, or multiple fractures closely for haemothorax risk, a study recommends.

New insights from a large-scale study reveal how humidity influences respiratory health, offering both protective benefits and potential risks to lung function.

Alcohol’s role in TB risk among diabetics: Moderate drinking may reduce risk, but heavy consumption sharply increases it, particularly for smokers.

Young adults with metabolic syndrome face a significantly increased risk of COPD development, emphasizing the importance of early monitoring and prevention.

Acute exacerbations significantly worsen survival in progressive pulmonary fibrosis, urging a need for targeted management strategies.

Asthma increases the risk of bronchiectasis, with sinusitis and eosinophilic inflammation acting as mediators, according to a new genetic study.

Nicotinamide riboside reduces airway inflammation and boosts NAD+ levels in COPD patients, study shows.

AI-powered urine biomarkers predict COPD exacerbations up to a week before symptoms, paving the way for early intervention.

Machine learning predicts occurrence and mortality of sepsis-associated ARDS with high accuracy, study reveals.

COVID-19 poses significantly higher risks for people with multiple long-term conditions, with increased rates of mortality and severe outcomes.

No difference in mortality found between indwelling pleural catheters and chemical pleurodesis for treating malignant pleural effusions.

Atomized indocyanine green inhalation enhances precision and recovery in paediatric lung surgeries, study finds.

Higher quality of life at admission predicts better outcomes for COPD patients with pneumonia, study shows.

Cumulative corticosteroid dose linked to pneumonia mortality risk in connective tissue disease patients, study finds.

New machine learning model predicts lung perfusion in PE patients from non-contrast CT scans, providing a safer alternative to standard imaging.

Regular physical activity reduces exacerbations in COPD patients using dual bronchodilators, study finds.

New research identifies six clinical phenotypes in young COVID-19 patients, offering insights for personalised paediatric care.

Long-term PAP therapy may boost survival in patients with COPD and OSA, highlighting potential benefits of early diagnosis and proactive respiratory management.

High Flow Nasal Cannula therapy may reduce the need for ventilation in severe COVID-19 cases, improving oxygenation and ICU outcomes.

A Swedish study, using data from the BAMSE birth cohort, has shown that childhood body mass index (BMI) trajectories can have lasting effects on lung health, with certain patterns linked to reduced lung function by early adulthood.

Recent studies and meta-analyses have investigated the impact of PM2.5 on asthma, yet findings remain inconsistent.

A NEW clinical trial has found that the asthma drug montelukast does not shorten the duration of symptoms for mild-to-moderate COVID-19 patients compared to a placebo.

A new study has shown that dual bronchodilator therapy can help reduce exacerbations in patients with chronic obstructive pulmonary disease (COPD), with notable differences in efficacy between current and former smokers.

Detection of SARS-CoV-2 RNA on the floors of healthcare worker-only areas in hospitals is strongly associated with impending COVID-19 outbreaks in hospital wards.

Findings from ERS 2024 show that continuing anticoagulation after the acute phase of COVID-19 significantly reduces the risk of venous thromboembolism in recovering patients.

A new study has found that both indoor and outdoor air pollution significantly worsen respiratory health in patients with COPD

A study shows that brief exposure to ultrafine particles in the air raises the risk of respiratory infections in children.

A new study reveals that people with schizophrenia treated with antipsychotics face higher risks of severe respiratory infections, particularly during the COVID-19 pandemic.

New research shows changes in haemoglobin levels can accurately detect hydrostatic pulmonary oedema in patients with acute dyspnoea

A study has revealed significant differences in influenza and COVID-19 vaccination rates among children receiving long-term ventilation through tracheostomy,

This research has added to the growing body of evidence about the negative long-term effects of vaping.

Research presented at the European Respiratory Society (ERS) Congress has revealed that prolonged exposure to air pollution increases the risk of hospitalisation for respiratory conditions

A recent study utilised AI to detect pulmonary embolism early using only patient records.

A recent study identified significant issues with the suboptimal use of inhalers among hospitalised patients with chronic obstructive pulmonary disease.

A recent study revealed the effectiveness of a tailored, interactive text message program designed to help adolescents quit vaping.

Patients with rheumatoid arthritis-associated interstitial lung disease face a significant risk of severe and often fatal infections, according to a new multicenter prospective study.

A new study found that 92% of patients hospitalised for COVID-19 still have lung lesions two years after discharge.

A study revealed that an AI model can accurately predict lung function metrics such as forced vital capacity and forced expiratory volume in 1 second from chest X-rays.  

A recent study shows many COVID-19 survivors have lasting lung issues and reduced pulmonary function three years post-hospitalization, highlighting the need for ongoing care.

A new study sheds light on the effects of obesity on patients undergoing extracorporeal membrane oxygenation, which is a critical intervention used when all other treatment methods fail.

A recent study suggests that nasal sprays coupled with physical activity and stress management could shorten the duration of respiratory infections, including colds and COVID-19

A RECENT study revealed a significant association between COVID-19 vaccination rates and decreased symptomatic asthma among children.

A recent study revealed that long-term exposure to air pollution during childhood can lead to bronchitis symptoms in adulthood.

A study shows that Indigenous children with bronchiectasis and low cough scores have higher odds of symptom resolution following a 14-day antibiotic treatment for non-severe exacerbations. 

A trial has found that using nasal high-flow oxygen during tubeless upper airway surgery in children does not reduce the frequency of interruptions for rescue oxygenation.

Early lung ultrasonography scores have been linked to future respiratory complications in preterm infants.

A recent study has highlighted the potential of a plant-based diet on reducing the risk of emphysema in young adults with a history of smoking.

Transitioning to race-neutral spirometry reference equations, changes lung function interpretations, potentially impacting treatment for children with chronic lung diseases.

Efficacy, safety, and tolerability of sulthiame (STM) was explored in a new study on the treatment of obstructive sleep apnea (OSA).

Efforts to address the pressing issue of psychological distress among survivors of critical illnesses were explored in a study that optimized a mobile mindfulness intervention app.

New study results highlight the effect of early diagnosis and treatment of undiagnosed asthma or chronic obstructive pulmonary disease.

A recent multicenter study has uncovered critical insights into the risks faced by patients with a history of acute pulmonary embolism during the COVID-19 pandemic.

A recent study investigated whether subtle abnormalities in lung tissue are linked to acute respiratory disease in people with a smoking history

Research has explored whether a plant-centred diet could lower the chances of developing emphysema