Respiratory

A long-term study finds sotatercept continues to improve outcomes in patients with pulmonary arterial hypertension, with manageable safety risks.

A mobile asthma self-management tool improved symptoms in adults with uncontrolled asthma, but its effectiveness varied across racial groups.

Scientists uncover shared genetic signals between chronic dry cough and ACE inhibitor-induced cough, pointing to neurological pathways as potential targets.

Tozorakimab shows potential benefit in patients with COPD with frequent exacerbations, despite primary endpoint not being met in overall population.

Macrophages in COPD lungs show elevated carbon loads, larger cell size, and enhanced inflammation, highlighting a potential driver of disease progression.

Paediatric-onset bronchiectasis leads to more severe disease than adult-onset, highlighting need for early, tailored care.

MiDAS, a new clinical tool, predicts poor outcomes in difficult asthma by scoring multimorbidity burden, highlighting the need for whole-patient care.

A post hoc analysis confirms dupilumab reduces key inflammatory biomarkers and COPD exacerbations, with highest benefit in patients with raised eosinophils and FeNO.