Respiratory

High cannabis use is associated with worse lung function, respiratory symptoms, and airway immune changes, highlighting potential clinical risks.

Meta-analysis links prior tuberculosis and chronic bronchitis to higher lung cancer risk in never-smokers, with implications for clinical risk assessment.

Therapist-guided internet CBT safely lowers asthma-related anxiety and boosts quality of life, control, and behaviour in adults with asthma.

A 1000 ng/mL D-dimer threshold safely rules out pulmonary embolism in low-likelihood patients, reducing unnecessary chest imaging in emergency care.

Combining a host biomarker with large language model analysis improves lower respiratory tract infection diagnosis in ICU patients, reducing uncertainty.

NHS opt-out tobacco dependency services boost quit attempts in deprived populations, but success lags, highlighting opportunities to reduce inequalities.

Medication-induced deep sedation in ICU patients is linked to loss of independence; lighter sedation and mobility improve outcomes, study finds.

A novel iPSC-derived lung-on-chip model mimics human alveolar tissue, revealing macrophage-driven tuberculosis responses.

Rare inherited genetic variants linked to mucin glycosylation and DNA repair significantly increase familial lung cancer risk, offering new targets for early detection.

New trial analysis shows COPD treatment withdrawal, including LAMA and ICS discontinuation, can trigger early exacerbation risk.

Sea saline nasal irrigation lowers bacterial colonisation and incidence of acute upper respiratory infections in children.

The nSOFA score predicts prolonged mechanical ventilation in newborns with NRDS. Early risk stratification may improve NICU care and outcomes.

Study shows that exhaled volatile organic compounds, including propanoic and nonanoic acids, could be used as non-invasive biomarkers for asthma.

New meta-analysis finds e-cigarette use may increase the risk of heart attack and stroke, even after adjusting for cigarette smoking.

Chronic bronchitis affects nearly 10% of adults in low- and middle-income countries, with links to worse respiratory outcomes.

New research identifies a specific monocyte gene signature that predicts mortality in IPF, offering potential targets precision medicine.

Gas stoves are a major source of indoor nitrogen dioxide, raising exposure levels WHO guidelines for millions of people.

Combining glecirasib and sitneprotafib shows encouraging efficacy and safety in patients with KRAS G12C-mutated NSCLC.

Over half of patients with severe asthma discontinued oral corticosteroids while maintaining disease control, major study finds.

Depression and anxiety increase asthma attack risk in adults, highlighting need for targeted care in those with comorbid mental health disorders.

Women show larger improvements in symptoms and wellbeing after lung volume reduction, despite similar physical changes to men.

A new score based on the 6-minute walk test helps predict serious outcomes in lung disease by combining symptoms, oxygen use, distance and oxygen levels.

Although genetic analysis shows little direct link between chronic respiratory and cardiovascular diseases, shared factors like smoking and inflammation drive risk in both conditions.

Maternal use of inhaled corticosteroids during pregnancy improves early lung function in infants born to asthmatic mothers. This intervention may reduce early respiratory risk.

New research reveals that abnormal chest X-ray results strongly predict future TB risk, emphasising the value of early screening.

A European survey of 470 clinicians shows major differences in how LAMAs are prescribed for severe asthma.

Fixed airway obstruction in severe asthma shows distinct clinical and biological traits, with some patients improving over time.

A 15-year study finds COPD patients with chronic respiratory failure face higher and earlier risks of heart disease, demonstrating the need for targeted screening.

Never-smokers with severe α1-antitrypsin deficiency can still develop lung disease, including emphysema, bronchiectasis, and airflow obstruction.

Study shows cigarette prices and age-of-sale laws impact youth smoking in the EU, with effects varying by region and gender.

Adjunctive low-dose glucocorticoids lower 30-day mortality in adults with community-acquired pneumonia in low-resource hospital settings.

A Swedish study found COVID-19 infection in pregnancy greatly raises preterm birth risk within 2 weeks, especially if unvaccinated. Vaccination offers key protection.

Tezepelumab reduced oral corticosteroid use in patients with severe asthma, with well-controlled asthma rising from 3% to 27% after 1 year.

Real-world study finds anti-IL5 therapy significantly reduces moderate and severe exacerbations in asthma and COPD patients, with major hospitalisation prevention.

Younger adults with early-onset lung cancer face poorer survival linked to late diagnosis, income, and access to care, highlighting urgent equity needs.

A Taiwanese study identifies lncZPBP2-3 as a pollution-responsive gene variant that heightens asthma risk with long-term PM2.5 exposure.

The MUSIC trial shows high-dose fluticasone elevates sputum bacterial load in severe COPD, without affecting upper airway microbiome, and ICS withdrawal can trigger exacerbations.

The ERS has released evidence-based guidelines for adult bronchiectasis care, offering structured recommendations on airway clearance, macrolides, and inhaled antibiotics.

Hypnosis can enhance comfort and clinical efficacy of non-invasive ventilation masks, reducing sedation needs and distress in acute respiratory failure patients.

New Mendelian randomisation study confirms a causal link between gut microbiota and childhood asthma.

A phase 3 trial found that retifanlimab plus chemotherapy significantly improved survival in patients with metastatic NSCLC, with a safety profile consistent with other PD-1 inhibitors.

New ERS 2025 research links paternal smoking in puberty with accelerated biological ageing in offspring, reinforcing evidence of intergenerational tobacco harms.

A multicentre study presented at ERS Congress 2025 found that remote monitoring reduced hospital visits and improved asthma control in children, strengthening the case for digital health in routine asthma care.

New research shows that paternal smoke exposure before puberty is associated with reduced lung function trajectories in offspring, increasing long-term respiratory risk.

A UK Biobank analysis presented at ERS Congress 2025 found that higher fruit intake reduced the negative effects of fine particulate air pollution on lung function, particularly in women.

The CHILD study analysis found that early exposure to higher levels of dog allergen reduced asthma risk and improved lung function at age 5, with effects modified by genetic background.

Robotic-assisted bronchoscopy with cone-beam CT achieved far higher diagnostic yields than conventional bronchoscopy, particularly for small and ground-glass lesions, offering a powerful new tool for early lung cancer diagnosis.

ECPR can restore circulation and tissue oxygenation, substantially improving survival and offering a favourable functional recovery.

A machine learning model combining CT radiomics with clinical data has shown accuracy comparable to experienced pulmonologists in diagnosing usual interstitial pneumonia and predicting survival outcomes.

A randomised trial finds that blowing a conch shell reduces daytime sleepiness, improves sleep quality, and lowers apnoea severity in people with obstructive sleep apnoea.

ERS/EULAR guidelines provide detailed recommendations for diagnosing, monitoring, and treating connective tissue disease-related interstitial lung disease, tailored to disease type and risk profile.

Study finds trained dogs detect lung cancer with 78% accuracy from breath samples versus 42% from saliva.

Hospital asthma exacerbations rise in later pregnancy, with reduced inhaled corticosteroid use a key modifiable risk factor, UK data show.

By 2050, nearly half of US adults aged 30–69 will have obstructive sleep apnoea, with cases rising to 76.6 million and the steepest growth seen in women.

Central tumour location linked to worse survival in lung cancer, suggesting need for closer post-operation monitoring.

Understand how an AI model uses chest CT scans to diagnose COPD with 95% accuracy.

A nearly three-decade study has revealed a significant rise in triazole-resistant Aspergillus fumigatus, a fungus responsible for invasive aspergillosis…

Study shows diets high in saturated fatty acids drive lung inflammation and worsen airway disease, similarly to obesity-related asthma.

Airway bacteria like Streptococcus oralis may boost natural immune defences, helping protect against pneumonia and viral infections, new research suggests.

COVID-19 infection raises risks of asthma, rhinitis, and sinusitis, while vaccination reduces respiratory type-2 inflammatory disease incidence.

Respiratory viruses such as influenza and SARS-CoV-2 can awaken dormant breast cancer cells, driving metastasis and raising mortality risk in cancer survivors, new research finds.

A registry-based analysis using Bayesian modelling has mapped the pathways linking biomarkers, lung function, and comorbidities to severe asthma exacerbation risk.

A UK registry study shows asthma biologics improve outcomes across BMI groups, but obese patients remain more likely to have uncontrolled disease.

A large pooled analysis shows that kidney problems are common in PAH and CTEPH, worsen survival, and see only minor improvement with current pulmonary hypertension therapies.

Meta-analysis confirms low income is linked to increased asthma exacerbations, especially in children, highlighting income inequality as a key risk factor.

A global trial finds a shorter all-oral regimen for pre-XDR tuberculosis fails to match the efficacy of standard care, with poorer results in those with extensive disease.

A new Europe-wide analysis reveals that RSV hospitalisations in older adults are far more common than previously reported, highlighting the importance of updated data in vaccine policy planning.

A new AI model shows promise in predicting survival in patients with fibrotic lung disease, offering more precise prognosis than standard tests and imaging methods.

Real-world study finds benralizumab leads to long-term clinical remission in up to 39% of patients with severe eosinophilic asthma.

Long-term exposure to fine particulate matter and nitrogen dioxide is linked to increased dementia risk, according to a major new meta-analysis involving over 24 million people.

A long-term study finds sotatercept continues to improve outcomes in patients with pulmonary arterial hypertension, with manageable safety risks.

A mobile asthma self-management tool improved symptoms in adults with uncontrolled asthma, but its effectiveness varied across racial groups.