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New Model Maps Pathways Driving Severe Asthma Exacerbation Risk

August 2025

A registry-based analysis using Bayesian modelling has mapped the pathways linking biomarkers, lung function, and comorbidities to severe asthma exacerbation risk.

Gene Therapy Shows Promise for Recurrent Respiratory Papillomatosis

A novel therapeutic vaccine, PRGN-2012, has shown promising results in treating recurrent respiratory papillomatosis.

Early CPAP Use May Lower Parkinson’s Risk in Sleep Apnoea

Obstructive sleep apnoea may increase the risk of developing Parkinson’s, but early treatment with continuous positive airway pressure therapy mitigates this risk.

IL-33 Inhibition Shows Promise in High-Risk COPD

IL-33 inhibition with tozorakimab may offer clinical benefits in patients with COPD at high risk of exacerbations.

E-Cigarette Use Linked to Altered Lung Function in Youth

Young adults who use e-cigarettes may experience changes in lung ventilation distribution, potentially indicating early small airway impairment.

Childhood BMI Linked to COPD Risk in Adulthood

Children with above-average BMI trajectories are at increased risk of developing chronic obstructive pulmonary disease later in life.

Minimal Residual Disease May Predict NSCLC Recurrence After Osimertinib

Molecular residual disease detection may help identify patients with EGFR-mutated NSCLC who could benefit from prolonged adjuvant osimertinib

Asthma Diagnostic Testing More Effective in the Morning

A new study highlights the significant impact of time of day and season on bronchodilator responsiveness.

Lung Cancer Screening Adherence Declines, Reducing Detection Rates

A multicentre cohort study found that adherence to annual lung cancer screening declines over time, with lower adherence linked to reduced lung cancer detection rates.

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