Rheumatology

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Cast Immobilisation for Unstable Ankle Fractures

February 2026

Cast immobilisation proved non-inferior to surgery for the treatment of unimalleolar Weber B ankle fractures with a congruent mortise on initial radiography but deemed unstable by external rotation stress testing.

Epstein–Barr Virus Antibodies Correlate With RA Activity

RA patients positive for anti-EBV EA-DR IgG antibodies show higher ACPA levels and increased disease activity, suggesting a link between Epstein–Barr virus immune responses and rheumatoid arthritis.

Axial Psoriatic Arthritis in Japan Shows Lower Disease Activity

ASAS-PerSpA study finds Japanese patients with axial psoriatic arthritis have lower disease activity and better function than other regions, with notable differences in treatment patterns.

Machine Learning Shows Promise in Predicting RA Treatment Response

A scoping review shows machine learning models may help predict response to biologic and targeted synthetic DMARDs in rheumatoid arthritis, though validation gaps remain.

Grip Strength Fails to Reflect Core Muscle Weakness in Axial Spondyloarthritis

A new study shows that grip strength cannot be used as a proxy for core muscle endurance in axial spondyloarthritis, highlighting the need for targeted core assessments.

Low Muscle Strength Linked to Fall Risk in Rheumatoid Arthritis

A six-year cohort study shows low muscle strength, not sarcopenia, is linked to increased falls risk in patients with rheumatoid arthritis, highlighting the importance of functional assessments.

SLE Linked to Reduced ICU Survival Through Renal Dysfunction

Critically ill patients with systemic lupus erythematosus show reduced ICU survival, driven largely by renal dysfunction, with glucocorticoids potentially mitigating mortality risk.

Biologic Switching Beats TNF Cycling in Psoriatic Arthritis

Real-world data show switching to IL-17 inhibitors after TNF inhibitor failure improves treatment retention compared with TNF cycling in psoriatic arthritis.

Kefir Shows Potential as a Natural Strategy for Osteoporosis Management

A new review highlights kefir-derived peptides, probiotics and kefiran as promising natural strategies for bone health and osteoporosis prevention.

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