Rheumatology

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Rheumatoid Arthritis Drug Linked to Lower Risk of Cervical Spine Damage

March 2025

A decade-long study has found that each year of infliximab use is linked to an 11% lower risk of cervical spine deformity in RA patients, potentially extending the known benefits of the drug beyond peripheral joints.

Wearable Device Reduces Fatigue and Raynaud Symptoms in Systemic Sclerosis

A wearable device reduced fatigue and Raynaud symptoms in systemic sclerosis, improving quality of life without adverse effects.

Early Menopause Raises Risk of ACPA-Negative Arthritis

A study revealed that early menopause and fewer reproductive years significantly increase the risk of ACPA-negative inflammatory arthritis.

Avacopan Shows Promise for ANCA-Associated Vasculitis Despite High Discontinuation Rates

A new Japanese retrospective study confirms that avacopan can effectively induce and sustain remission in patients with ANCA-associated vasculitis, reducing the need for glucocorticoids.

Fewer Gout Flares and Improved Lipid Profile Seen with Urine Alkalization Therapy

A new study revealed that adding urine alkalization therapy to febuxostat treatment in gout patients with low urinary pH leads to fewer flares, improved kidney health, and better lipid profiles.

AI-Driven Model CAPI-Detect Improves Diagnosis of Systemic Sclerosis

A new machine learning model, CAPI-Detect, has demonstrated over 90% accuracy in diagnosing systemic sclerosis (SSc) using nailfold videocapillaroscopy (NVC).

Women on Menopausal Hormone Therapy Face Higher Risk of Lupus and Scleroderma

A new study suggests that menopausal hormone therapy (MHT) may increase the risk of systemic lupus erythematosus and systemic sclerosis.

Secukinumab Proves Effective in Real-World Psoriatic Arthritis Treatment

Secukinumab shows high drug survival and sustained effectiveness in psoriatic arthritis patients, with better outcomes in mixed peripheral and axial involvement.

Joint-Specific Responses to TNFi in Psoriatic Arthritis Revealed in European Study

A study of over 1,700 psoriatic arthritis patients across nine European countries reveals that tumor necrosis factor inhibitors (TNFi) work differently depending on the affected joint.

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