Rheumatology

A prospective study found higher pregnancy complication rates in women with lupus who were not in remission, particularly among high-risk patients.

Peresolimab has been linked to fewer PD-1 high-expressing CD4 T cells and neutrophils, and reduced inflammatory signalling in rheumatoid arthritis.

Plasma protein signatures have been associated with high structural damage in ankylosing spondylitis, with potential to complement imaging assessment.

Rituximab, mycophenolate mofetil, and cyclophosphamide strategies have shown no significant differences in 52-week outcomes in SLE with lupus nephritis.

Advanced therapies have not been linked to clearly different cancer risks in patients with rheumatoid arthritis and prior cancer, a new study has shown.

A cohort of 12,731 patients showed that primary Sjögren’s disease is linked to higher risks of cognitive disorders and dementia, supporting clinical attention to cognition across age groups.

A narrative review has found obesity pharmacotherapy relieves osteoarthritis pain, but evidence of structural joint modification has remained absent.

A South Korean cohort study of over 1.2 million adults found alcohol consumption was linked to a dose-dependent rise in osteoarthritis risk.