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Hemodialysis on Cutaneous Manifestations of Chronic Kidney Disease
8
Mins
April 2024
Chronic kidney disease (CKD) is a non-communicable disease that currently widely affects around 850 million people. Nowadays…
Read more
8
Mins
23rd April 2024
Hemodialysis on Cutaneous Manifestations of Chronic Kidney Disease
Chronic kidney disease (CKD) is a non-communicable disease that currently widely affects around 850 million people. Nowadays…
6
Mins
23rd April 2024
Effects of Dermal Fillers on Vaginal Laxity and Female Sexual Function: A Minimally Invasive Procedure for Vaginal Rejuvenation
Female health has become one of the most discussed issues today. Many problems, like uterine prolapse, birth injuries, incontinence…
3
Mins
10th April 2024
Roundtable Interview: Neal Bhatia, Brian Hibler, Jacqueline Watchmaker
I am Director of Clinical Dermatology at Therapeutics Clinical Research in San Diego, California, USA, where my practice is 70% research…
2
Mins
5th April 2024
Interview: Michael Gold
My interest in dermatology comes from the fact that, as a teenager, I had bad acne. I was fortunate to have seen Albert Kligman…
3
Mins
3rd April 2024
Interview: Andrew Alexis
My inspiration to pursue dermatology begins with my mother, the late Mercy Alexis Akuffo, who was the first Black female dermatologis…
4
Mins
26th March 2024
Treating Severe Unresponsive Alopecia Areata with Baricitinib
Among the different types of alopecia, alopecia areata (AA) is the most common reason of hair loss worldwide that is attributed to…
1
Mins
12th February 2024
Author Response to: Letter To the Editor Concerning ‘Lichen Sclerosus in Prepubertal Males: Breaking the Paradigm’
The aim of our work was to underline that surgery can be applied as a first-line treatment. This was also the shared starting assumption…
15
Mins
30th January 2024
Exploring Advancements and Challenges in Adjuvant Melanoma Treatment
Melanoma of the skin is a common type of cancer that primarily affects younger patients. In Stage III melanoma, which does not involve…
1
Mins
25th January 2024
Letter To the Editor Concerning ‘Lichen Sclerosus in Prepubertal Males: Breaking the Paradigm’
We agree that the topic of treatment of penile lichen sclerosus in boys is important, and needs more attention in clinical research and…
7
Mins
23rd November 2023
Bimekizumab 3-Year Efficacy in Patients with Moderate-to-Severe Plaque Psoriasis: Response Maintenance, Re-treatment, and Effect on High-Impact Areas
Psoriasis symptoms can be not only uncomfortable, irritating, and painful, but can also impact several aspects of a patients’ daily life…
8
Mins
23rd November 2023
Secukinumab for Patients with Moderate-to-Severe Hidradenitis Suppurativa: Post Hoc Analyses of Efficacy Endpoints, Draining Tunnels, Skin Pain, and Work Productivity
Due to the clinical heterogenicity of HS, assessment of disease severity is complex, and over 20 different outcome measures have…
2
Mins
23rd November 2023
Efficacy and Safety of Upadacitinib in a Phase II Randomised, Double-Blind, Dose-Ranging Study of Adults with Extensive Non-segmental Vitiligo
Vitiligo is an autoimmune skin disorder that causes depigmentation of the skin and/or leukotrichia of the hair, resulting from the…
10
Mins
23rd November 2023
A New Landmark for Wellbeing in Psoriasis: The POSITIVE Study
Psoriatic disease is a chronic, inflammatory immune condition affecting more than 40 million individuals worldwide…
13
Mins
17th November 2023
Platelet-Rich Plasma Applications, The Past 5 Years
This review article aims to provide an overview of platelet-rich plasma’s applications and evidence over the past 5 years in randomised…
9
Mins
26th October 2023
Editor's Pick: Diagnostic Evaluation of Hair Loss: A Narrative Review
This review provides a systematic approach for dermatologists to use in order to accurately diagnose hair loss disorders…
10
Mins
12th October 2023
Patient Centricity in Skin Treatments: Global Meeting of Experts in Dermatology
During this symposium, global experts in dermatology gave a series of lectures focused on skin treatments and their benefits for patients…
5
Mins
5th October 2023
Mycosis Fungoides Palmaris et Plantaris Progressing to Complete Early-Stage Disease Improved with Phototherapy
Mycosis fungoides is the most common form of cutaneous T cell lymphoma. In this article, the authors describe a case of a 53-year-old…
8
Mins
5th September 2023
Editor’s Pick: Assessing the Relationship Between Vitiligo and Cardiovascular Disease Risk Factors
Vitiligo is an autoimmune disorder characterised by the loss of melanocytes, resulting in white, depigmented cutaneous macules…
6
Mins
9th August 2023
Collagen-Filler Injection Associated Dermopathy and COVID-19
COVID-19 and cosmetic skin-fillers are two prevalent topics of today’s medicine, yet their interaction is not sufficiently studied. This…
5
Mins
8th August 2023
Systemic Sclerosis Manifesting Post-Radiotherapy: A Case Report
Morphoea causes skin and subcutaneous tissue fibrosis, and can sometimes involve the fascia, muscle, or bone. Sclerosis usually begins as…
7
Mins
24th July 2023
Progressive Facial Hemiatrophy (Parry–Romberg Syndrome) Treated with Hyaluronic Acid Fillers
Parry–Romberg syndrome (PRS) is a rare neurocutaneous condition that can affect the skin, subcutaneous fat, muscle, and bone on one side…
11
Mins
15th June 2023
Elevating Aesthetics: Patient-Specific Treatment with Hyaluronic Acid Fillers to Improve Appearance and Psychosocial Wellbeing
This review of the ‘Elevating Aesthetics’ symposium held at the International Master Course on Aging Science (IMCAS) 2023 shares insights…
3
Mins
31st May 2023
Interview: Edel O’Toole
I was always interested in biology and science. As a child, I loved identifying wild flowers and this is not all that dissimilar to…
7
Mins
23rd May 2023
Interview: Christopher Griffiths
There were actually two reasons. When I was about 4 years old, I was given a bird book by my parents and I memorised every bird…
3
Mins
16th May 2023
Cutaneous Squamous Cell Carcinoma of the Hand Presenting as Clinical Perineural Invasion
Cutaneous squamous cell carcinoma (SCC) contributes to 20% of non-melanoma skin cancers and early diagnosis is vital to reducing…
11
Mins
12th April 2023
IL-17 and -23 Inhibitors for the Treatment of Psoriasis
Psoriasis is a chronic inflammatory skin disorder affecting approximately 60 million people worldwide. The condition presents with rapid hyperproliferation and dysregulated differentiation of epidermal keratinocytes, manifesting clinically as salmon pink plaques with overlying silvery-white scale.
25th November 2022
Clinical Efficacy and Outcomes of Remibrutinib (LOU064) in Patients with Chronic Spontaneous Urticaria Inadequately Controlled with H1-Antihistamines: Findings from a Phase IIb Study
As part of the 31st European Academy of Dermatology and Venereology (EADV) Annual Congress held in Milan, Italy, and online, 7th–10th September 2022, five poster presentations outlined results from the Phase IIb study of remibrutinib (LOU064) in patients with chronic spontaneous urticaria inadequately controlled with H1-antihistamines.
11
Mins
14th November 2022
An Overview of the EORTC-CLTG 2022 Congress
This year’s European Organisation for Research and Treatment of Cancer (EORTC) Cutaneous Lymphoma Tumours Group (CLTG) Annual Meeting was held in Madrid, Spain. Presentations covered a broad range of topics in the field of cutaneous lymphomas, from molecular mechanisms, through diagnostics and prediction of prognosis, to skin-directed and targeted therapies, combination therapies, and patient-reported outcomes.
6
Mins
20th October 2022
Photoprotection and the Science Behind Skin Healing
Sun exposure can lead to tanning, but also to skin damage due to the actions of ultraviolet A and B, visible light, and infrared radiation. One result of sun exposure is field cancerisation (FC), the precursor to actinic keratosis (AK), which in turn is a risk factor for, most notably, squamous cell carcinoma.
6
Mins
20th October 2022
Clinical Efficacy and Outcomes of Remibrutinib (LOU064) in Patients with Chronic Spontaneous Urticaria Inadequately Controlled with H1-Antihistamines: Findings from a Phase IIb Study
Chronic spontaneous urticaria (CSU) is characterised by the spontaneous occurrence of wheals (hives) and/or angioedema for ≥6 weeks.1 CSU can persist for several years and is associated with severe pruritus. Skin mast cell activation in CSU occurs via Type I autoallergy driven by IgE to autoallergens, and a Type IIb autoimmune response due to mast cell-targeted autoantibodies against IgE or high-affinity IgE receptor.
5
Mins
20th October 2022
Secukinumab in Moderate-to-Severe Hidradenitis Suppurativa: Primary Endpoint Analysis from the SUNSHINE and SUNRISE Phase III Trials
The primary endpoint analyses from the SUNSHINE and SUNRISE Phase III trials of secukinumab in moderate-to-severe hidradenitis suppurativa (HS) were featured in an oral presentation as part of the late-breaking news session at the 31st annual European Academy of Dermatology and Venereology (EADV) congress. Known collectively as the SUNNY trials, the SUNSHINE and SUNRISE studies represent the largest Phase III trials conducted in HS to date.
5
Mins
4th July 2022
Editor's Pick: Pemphigus Vulgaris and Pemphigus Foliaceus: A Single-Centre Comparative Study in Rabat, Morocco
Pemphigus is a group of rare autoimmune blistering diseases affecting the skin and mucous membranes. Pemphigus foliaceus (PF)…
9
Mins
16th June 2022
Beyond Aesthetics: Hyaluronic Acid Fillers as a Therapeutic Treatment
Any filler injection requires a bespoke treatment approach and a thorough anatomy knowledge to minimise procedural risks and achieve…
10
Mins
30th May 2022
A Retrospective Database Cohort Study Evaluating the Association Between Immune Suppressive Therapy and the Development of Cancer in Patients with Atopic Dermatitis Within UK Primary Care
Atopic dermatitis (AD) is the most common inflammatory skin condition, affecting 11–20% of children and 5–10% of adults…
7
Mins
9th May 2022
Trichotillomania with Giant Gastric Trichobezoar in a Female Child: A Case Report
Trichotillomania is defined by the Diagnostics and Statistic Manual of Mental Disorders (DSM-5) as an individual repetitively pulling…
5
Mins
2nd May 2022
Varicella Zoster Reactivation Following mRNA Vaccination: Two Case Reports and a Review of Cutaneous Adverse Events of COVID-19 Vaccines
Varicella Zoster reactivation and cutaneous reaction as a mRNA vaccine side effect following COVID 19 vaccination…
4
Mins
28th April 2022
Case Report of Epstein–Barr Virus-Induced Autoimmune Vitiligo in Nigeria
Vitiligo is an acquired skin depigmenting disorder resulting from melanocytes loss in the epidermis, associated with an autoimmune aetiopathophysiology. However, there are limited data about the association between vitiligo and Epstein–Barr virus (EBV).
5
Mins
11th April 2022
Severe Sunburn-Like Adverse Cutaneous Drug Reaction in a Patient on Treatment with Rifaximin: A Rare Case of Acute Phototoxic Drug Reaction
Drug-induced photosensitivity is an adverse cutaneous reaction caused by a simultaneous exposure to potentially photosensitising drugs (via topical application or parenteral administration) and ultraviolet (UV) radiation or visible light.
6
Mins
2nd March 2022
Revolution in Photoprotection: How to Recommend and Adapt Photoprotection According to Skin Phototype and Dermatoses
The solar spectrum is composed of various wavelengths of electromagnetic radiation that can penetrate the skin to different levels: the longer…
4
Mins
21st February 2022
Paget Disease of Skin Secondary to Urothelial Carcinoma
Currently, the exact mechanism underlying EMPD is unknown, but two widely known theories exist, namely the epidermotropic and transformation theories.
5
Mins
21st February 2022
Treatment with Hyaluronic Acid Injections in a Patient with Craniosynostosis
A case of a 25-year-old White female left with residual bone deformity after surgical correction of craniosynostosis during childhood…
5
Mins
3rd February 2022
Latest Highlights on Biologic Treatments for Psoriasis and Psoriatic Arthritis from the EADV 2021
The latest research on autoimmune skin disease has studied the efficacy and safety characterisation of guselkumab (GUS), a human monoclonal…
10
Mins
3rd February 2022
Diving Deep: Harnessing the Potential of the IL-23 Pathway
Strober began by summarising his opinion on the key characteristics of anti-IL-23 therapies that support their efficacy for inducing…
6
Mins
17th January 2022
Dermatophyte Monitoring in an Iranian Training Dermatology Hospital
Dermatophytes are the keratinophilic moulds living on the superficial layer of human and animal skin and are transmitted by direct and…
4
Mins
11th November 2021
Eleven Myths on Nail Melanoma
A number of misconceptions prevail in nail melanoma. This short essay tries to clarify some of these issues.
4
Mins
11th November 2021
Interview: Peter Lio
Interviewing Peter Lio, Clinical Assistant Professor of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine
8
Mins
11th November 2021
The Benefits of Achieving Complete Control in Patients with Chronic Spontaneous Urticaria
The latest international guidelines on urticaria were published in September as a joint initiative from the European Academy of…
10
Mins
11th November 2021
Tailored Injection Techniques in the Mid- and Lower Face Using a Multilayering Approach
Recent years have witnessed significant advances in the understanding of facial anatomy. Extensive studies have uncovered the arrangement of soft-tissue layers underlying the skin and their mobility during expression. Meanwhile, increasing awareness of the facial vascular network has laid the foundation for lower risk cosmetic procedures.
3
Mins
11th November 2021
Interview: Roxana Daneshjou
An interview with Roxana Daneshjou, Clinical Scholar of Dermatology, Stanford University, California, USA.
7
Mins
11th November 2021
Mosaicism in Tuberous Sclerosis Complex: A Case Report, Literature Review, and Original Data from Danish Hospitals
Tuberous sclerosis complex (TSC) is an autosomal dominant hereditary disease with hamartomatous growths in multiple organs due to…
9
Mins
11th November 2021
Emerging Treatment Regimens in Psoriasis: Are There Advantages Over Current Biologic Therapies?
Psoriasis is a chronic inflammatory skin condition that impacts patients’ quality of life and has large economic consequences…
10
Mins
22nd October 2021
Patient-Reported Outcomes with Monoclonal Antibody Therapies in Patients with Moderate-to-Severe Plaque Psoriasis
Richard B. Warren highlighted Psoriasis Symptoms and Impacts Measure (P-SIM) responses from the Phase III BE VIVID trial in patients…
10
Mins
20th October 2021
Efficacy and Safety of Monoclonal Antibody Therapies in Patients with Moderate-to-Severe Plaque Psoriasis
In the late-breaking research sessions, Reich presented BE RADIANT, the first Phase III trial to compare inhibition of IL-17A and IL-17F…
6
Mins
15th October 2021
Where Do We Begin? The Key Role of the IL-23 Pathway in Psoriasis and Psoriatic Arthritis
This Janssen-sponsored live satellite symposium, entitled ‘Where do we begin? The key role of the IL-23 pathway in psoriasis and psoriatic…
9
Mins
17th June 2021
Pioneering Best Practices in Atopic Dermatitis: Results from the Quality of Care Initiative
Pioneering global best practices in atopic dermatitis (AD) and implementing them in the clinic are important steps towards optimising patient care…
11
Mins
17th May 2021
Botulinum Toxins in Medical and Cosmetic Dermatology
Botulinum neurotoxins (BoNTs) are derived from Clostridium botulinum, a gram-positive anaerobe. While there are seven subtypes of BoNT (A to G), only A…
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