Dermatology

A targeted rituximab infusion at 6 months, based on relapse predictors, significantly reduced pemphigus recurrence at one year.

Neoadjuvant T-VEC achieves resectability in 50% of difficult-to-treat BCC cases, improving outcomes without extensive reconstructive surgery.

Studies have shown that psoriasis patients exhibit elevated intestinal permeability, correlating with gastrointestinal discomfort.

Diabetes was investigated in five studies, with only one demonstrating a correlation between the condition and higher hospital readmission rates.

A recent study examined the scalp microbiome in Black women diagnosed with central centrifugal cicatricial alopecia, compared with matched healthy individuals.

A recent qualitative study has provided valuable insights into the experiences of Latine patients in the US living with moderate to severe psoriasis.

A gut-derived bacterial compound significantly slows vitiligo progression in mice, offering new hope for treatment and repigmentation.

Potent corticosteroids provide superior symptom relief for moderate atopic dermatitis flare-ups in children, enhancing primary care management.

This study aimed to evaluate whether novel biologics pose different risks of major adverse cardiovascular events compared with tumour necrosis factor inhibitors.

A recent multicentre, randomised clinical trial aimed to evaluate the efficacy and safety of combining baricitinib, with narrowband UV-B phototherapy in adults with severe, active, nonsegmental vitiligo.

Individuals with Down syndrome exhibit a hyperactive immune system marked by increased interferon signalling and cytokine production.

Recent research has investigated the efficacy of excimer light and topical methotrexate 1% hydrogel in managing scalp psoriasis.

A study leveraging social media platforms explored topical steroid withdrawal among individuals with atopic dermatitis.

The study revealed that 22.5% of patients experienced acne relapse, and 8.2% required isotretinoin retrial.

A comprehensive study of 2,657 patients assessed the relationship between chronic inflammatory disease comorbidities and alopecia areata characteristics.

Combining fractional CO2 laser with topical dutasteride improves androgenic alopecia outcomes compared to laser treatment alone.

The visible nature of dermatological symptoms exacerbates their impact, often leading to stigma, social withdrawal, and psychological distress, including anxiety and depression.

Genetic testing reveals key variants in palmoplantar keratoderma, aiding diagnosis and subtype differentiation.

COVID-19 increases the long-term risk of autoimmune disorders, especially in severe cases and unvaccinated individuals.

Cutaneous chronic graft-versus-host disease impairs quality of life, affecting social, psychological, physical functioning, and health perceptions.

Self-guided online CBT is noninferior to clinician-guided CBT for atopic dermatitis, offering effective and resource-efficient treatment.

Shared genetic, environmental, and microbial factors suggest a potential relationship between these diseases.

Given these results, patients with cutaneous lupus erythematosus may benefit from increased vigilance in cardiovascular screening and management.

Across both trial phases, adverse events were primarily mild to moderate, with no drug-related serious incidents reported.

The results suggest that while indoor tanning is a well-established risk factor for melanoma, it does not appear to contribute to tumour mutational burden in cutaneous melanoma tumours.

Improvement or stability of alopecia was observed in all patients after 3–6 months of low-dose oral minoxidil use.

Tapinarof cream 1%, a novel nonsteroidal aryl hydrocarbon receptor agonist, has emerged as a promising solution for plaque psoriasis.

A new study reveals that many acne-specific patient-reported outcome measures lack LGBTQ+-inclusive language, potentially undermining care for diverse patient populations.

Individuals with active psoriasis displayed a lower proportion of females and were more likely to be obese.

Low-dose oral minoxidil has emerged as a promising off-label treatment for hair loss.

Reflectance confocal microscopy is revolutionising dermatological imaging by providing non-invasive, detailed images of skin tissues.

Nutritional therapies, along with probiotic treatments, offer a holistic approach to managing these conditions by addressing both physiological and psychological symptoms.

Study reveals UV radiation and Merkel cell polyomavirus are major drivers of Merkel cell carcinoma in the US.

The study demonstrated that baricitinib significantly improved clinical signs of moderate-to-severe atopic dermatitis in children and adolescents at 16 weeks.

Rocatinlimab, a monoclonal antibody targeting the OX40 receptor on T cells, offers a novel approach to treating atopic dermatitis.

At week 16, dupilumab demonstrated significant benefits compared to placebo, regardless of the presence of asthma or AR.

Conditions such as cerebral infarction, acute myocardial infarction, pulmonary embolism, and venous thrombosis were more prevalent among those with vitiligo.

This study reinforces teledermoscopy’s utility for triaging skin lesions and prioritising high-risk cases for in-person care.

The findings suggest that healthcare systems must prioritise post-COVID-19 care, with a focus on identifying and managing autoimmune and autoinflammatory disorders.

A recent systematic review and meta-analysis reveals dermatologists have a significantly higher accuracy in diagnosing skin cancer