Flagship Journal

Dr Imran Ahmad. Consultant Anaesthetist and Deputy Clinical Director for Theatres, Anaesthetics and Peri-operative Medicine, Guy’s and St Thomas’ NHS Foundation Trust, UK; President, Difficult Airway Society (DAS); Honorary Clinical Lecturer, King’s College London, UK.

Measurement of fluid biomarkers of neurodegeneration is an emerging approach offering improved diagnostic accuracy of neuropsychiatric conditions, particularly for atypical presentations. This article reports a case where the diagnosis of delirium with dementia was revised based on biomarker analysis, enabling treatment of a primary mood disorder with resolution of recurrent disabling psychiatric symptoms.

Peter Gill | Staff Paediatrician and Associate Scientist, The Hospital for Sick Children and SickKids Research Institute, Toronto, Canada; Assistant Professor, Department of Paediatrics and Institute of Health Policy, Management and Evaluation, University of Toronto, Canada

Damian Roland | Head of Service, Children’s Emergency Department, Leicester Royal Infirmary, UK; Honorary Professor, Population Health Sciences, University of Leicester, UK

In the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), Alzheimer’s disease (AD [named after the German psychiatrist and neuropathologist, Alois Alzheimer, who first described it]), is considered as a major or mild neuro-cognitive disorder…

Chronic pelvic pain (CPP) affects up to 25% of females of reproductive age, and 15% of all females worldwide. It is a common complaint of females visiting the gynaecology outpatient department.

This case report aims to unveil the possible differentials and processes involved in the diagnosis of marantic endocarditis…

Caseous mitral annular calcification (CMAC), sometimes called liquefaction necrosis of mitral annular calcification (MAC), is a rare variant of MAC, a chronic degenerative process that progresses with age.