Gastroenterology

New research shows supervised machine learning models combining Helicobacter pylori genomic data with patient demographics can accurately predict gastric cancer risk.

Current drinkers with an average lifetime alcohol intake of 14 or more drinks per week had a 25% higher risk of colorectal cancer.

A cross-sectional study shows resilience mediates the relationship between cognitive flexibility and psychological well-being in irritable bowel syndrome, identifying potential targets for psychological intervention.

New real-world data suggest early lactate clearance can predict massive transfusion needs in upper gastrointestinal bleeding, improving early risk stratification when combined with the Glasgow-Blatchford score.

A large network meta-analysis finds dual therapy for Helicobacter pylori offers comparable eradication rates with fewer side effects and better compliance than triple or quadruple regimens.

Real-world data show how microbiological findings and patient factors can guide empirical antibiotic choice in acute cholangitis, supporting carbapenem-sparing strategies in selected patients.

Real-world data show distinct determinants of health-related quality of life in Crohn’s disease and ulcerative colitis, highlighting phenotype-specific roles of inflammation, imaging findings, treatment burden, and modifiable risk factors.

A decade-long retrospective study shows IgG4-related cholangitis responds well to steroids, with low mortality and no progression to cholangiocarcinoma.