Gastroenterology

New data from Ontario reveals a concerning rise in alcohol-related gastrointestinal diseases among people aged 13 to 39, with young women showing the steepest increase.

Researchers report that a novel cap-assisted clip closure technique shortens procedure time without compromising safety in patients undergoing endoscopic tumour resection.

New research suggests matcha may offer greater protection than green tea against intestinal injury caused by gamma radiation, via the TAK1–TAB pathway.

A new study links high glycemic index and load diets with increased risk of pancreatic steatosis, while fibre intake appears protective.

A new mobile app is helping doctors adhere to colorectal cancer screening guidelines, reducing unnecessary colonoscopies while identifying high-risk patients needing intensive follow-up.

A large international study shows that intestinal ultrasound during pregnancy can reveal hidden inflammatory bowel disease activity, significantly improving prediction of complications like preterm birth and preeclampsia, beyond what clinical symptoms and lab tests can detect.

New findings from a decades-long study of over 470,000 adults show that higher calcium intake may significantly reduce the risk of colorectal cancer, regardless of whether it comes from dairy, non-dairy foods, or supplements.

A novel minimally invasive endoscopic technique has proven safe and effective in removing gastric fundal subepithelial lesions, including low-risk GISTs, according to a recent study.

A novel IgG-guided elimination diet shows potential in reducing abdominal pain in patients with irritable bowel syndrome.

A new study found that children with COVID-19 have a 25% higher risk of developing persistent gastrointestinal symptoms months after infection.

Despite the significant health burden, there are gaps in managing alcohol-related digestive diseases.

A new blood test, PAC-MANN-1, could dramatically improve early detection of pancreatic cancer, one of the deadliest malignancies.

Garlic intake has long been touted for its health benefits, but new research suggests it may increase the risk of atrophic gastritis in individuals with H. pylori infections.

A randomised controlled trial in Japan suggests that nature exposure in early childhood may reduce GI symptoms, lower stress levels, and enhance gut microbiota diversity.

Ursodeoxycholic acid (UDCA) may provide a safe and effective alternative to surgery for dissolving gallstones in patients who have undergone sleeve gastrectomy, according to a new study. Gallstones dissolved in 60% of patients treated with UDCA, with fewer hospitalisations and mild side effects.

New study finds taking weight-loss drug semaglutide before bariatric surgery doesn’t improve overall weight loss or safety outcomes.

A decade-long study reveals that Roux-en-Y gastric bypass offers better long-term weight loss and GERD control compared to sleeve gastrectomy in patients with severe obesity. The findings may influence surgical decision-making for obesity management.

A machine learning model using XGBoost has been shown to outperform traditional clinical risk scoring systems in predicting mortality risk for ICU patients with acute pancreatitis.

A multicenter study has identified key prognostic factors in high-risk GIST patients, including preoperative inflammatory markers, mitotic index, and adherence to imatinib therapy.

Study reveals gut microbiota families linked to FMT success in ulcerative colitis patients, offering early treatment insights.

A machine learning model has been developed to predict the need for temporary stoma formation after intestinal resection in Crohn’s disease patients.

Researchers have identified key biomarkers that could help distinguish between uncomplicated and complicated appendicitis, allowing for earlier and more accurate diagnosis. The study found that Red Cell Distribution Width (RDW), Mean Platelet Volume (MPV), and appendix diameter are reliable indicators of appendicitis severity.

A new blood test, PAC-MANN, shows promise for early detection of pancreatic cancer, improving treatment options and survival rates.

A new study suggests that infants who consume a high-fibre diet before their first birthday may have a significantly lower risk of developing celiac disease.

A new study in BMC Gastroenterology confirms that fecal calprotectin (FC) from ileostomy output is a highly sensitive biomarker for detecting small bowel inflammation in postoperative Crohn’s disease patients.

A groundbreaking multicenter clinical trial has found that a personalized elimination diet guided by an IBS-specific IgG antibody assay significantly reduces abdominal pain intensity and symptoms in IBS patients.

A new study highlights that IBD patients, especially those with ulcerative colitis, are at significantly higher risk of Clostridioides difficile infection (CDI).

A UK Biobank study has revealed that central obesity, measured by waist circumference and waist-to-hip ratio, may be a stronger predictor of colorectal cancer risk than BMI.

A major NHS study has found significant ethnic disparities in colorectal cancer diagnosis, with non-white patients more likely to develop early-onset CRC but less likely to be diagnosed through urgent referrals.

New research published in has identified highly specific gut microbiome signatures linked to non-alcoholic fatty liver disease (NAFLD).

A new study has found that combining probiotics with immune checkpoint inhibitors and chemotherapy significantly improves survival rates, intestinal health, and immune response in patients with metastatic colorectal cancer.

Adding high-dose intravenous vitamin C to standard chemotherapy significantly improves survival in patients with metastatic pancreatic cancer.

A new study has found that severe dysphagia significantly worsens survival rates in patients undergoing percutaneous endoscopic gastrostomy (PEG).

A recent study analysing data from the NHANES database (2007–2010) reveals a compelling link between oxidative balance and bowel health, with notable differences between men and women.

A large-scale study of over 540,000 women reveals the protective role of calcium and dairy against colorectal cancer while highlighting risks linked to alcohol and red meat consumption.

Adhering to the Mediterranean diet may improve outcomes in newly diagnosed Crohn’s disease by reducing inflammation and promoting a healthier gut microbiome, a new study reveals.

Wearable devices like Apple Watches, Fitbits, and Oura Rings could revolutionise inflammatory bowel disease (IBD) management.

A new meta-analysis has provided further insight into the effects of time-restricted eating combined with exercise on body composition.

A recent study highlights the long-term benefits of bariatric surgery in preventing the progression from pre-diabetes to Type 2 diabetes.

While AI-assisted colonoscopy improves adenoma detection rates, it also increases the detection of non-neoplastic lesions.

The sequence of biologic treatments in patients with inflammatory bowel disease significantly affects their risk of adverse clinical outcomes.

Tulisokibart, a TNF–like cytokine 1A monoclonal antibody, has demonstrated significant potential in inducing clinical remission in patients with ulcerative colitis.

A new integrative risk score predicts the risk of Crohn’s disease in healthy first-degree relatives of individuals with the disease.

The latest clinical guidelines from the American College of Gastroenterology (ACG) aim to improve the diagnosis and treatment of eosinophilic oesophagitis.

A centralised, mailed colorectal cancer screening programme significantly improved screening completion rates in federally qualified health centres.

The ALLEGRO trial aimed to determine whether 2% IV lidocaine could speed up the return of gut function following colon resection surgery.

Top-down treatment for newly diagnosed Crohn’s disease significantly outperforms the conventional accelerated step-up approach.

Dietary treatments may be more effective than pharmacological options for managing irritable bowel syndrome (IBS) symptoms.

The pioneering COLO-DETECT trial has demonstrated the potential of AI to significantly enhance the detection of colorectal polyps during colonoscopies.

A comprehensive meta-analysis has identified key risk factors associated with inadequate bowel preparation before colonoscopy.

Upadacitinib may offer superior disease management than tofacitinib for patients with ulcerative colitis.

Patients with painful chronic pancreatitis and a dilated pancreatic duct benefit more from early surgery than an endoscopy-first approach.

A new cohort study highlights significant racial and ethnic disparities in mortality rates associated with early-onset colorectal cancer.

While a gluten-free diet improves wellbeing, it does not fully reverse coeliac disease impact on gut function or microbiota composition, according to new research.

The 10-year study challenges previous assumptions about gastric cancer risks in Western populations, particularly among Caucasian Americans.

CVS can be highly disabling, but prompt recognition and effective management can dramatically improve patients’ quality of life.

Recent research has revealed significant regional disparities in the performance of computer-aided diagnosis (CADx) systems during colonoscopy.

Higher use of televisit services, via video or phone, was linked to a reduced likelihood of hospitalisation.

A new multisociety clinical guide provides a framework for GLP-1RA usage to ensure safe patient management.

Beer-only consumers may face greater health risks due to poorer dietary habits and unhealthy lifestyle factors.

The American Gastroenterological Association has released a new set of guidelines to assist healthcare providers in the pharmacological management of moderate-to-severe ulcerative colitis.

Individuals without a family history of colorectal cancer could safely extend their colonoscopy screenings from the standard 10-year interval to 15 years.

A systematic review investigating the impact of glucagon-like peptide-1 receptor agonists on alcohol consumption has yielded some promising results.

A large-scale analysis has revealed a significant link between coffee consumption and the gut microbiome, driven primarily by the presence of Lawsonibacter asaccharolyticus.

Gastroparesis diagnoses based solely on gastric emptying studies may overlook broader gastrointestinal dysmotility, necessitating a shift in diagnostic approaches.

New research highlights the utility of the PRECISE-DAPT score in predicting GI bleeding risk in patients undergoing dual antiplatelet therapy after percutaneous coronary intervention.

Findings indicated that patients taking ARBs had a higher likelihood of experiencing persistent symptoms and markers of poor small bowel healing.

Certain obesity types significantly increase risk of death in individuals with digestive diseases, according to a recent study analysing obesity’s impact on mortality.

A retrospective study analysed over 15 years of follow-up data from patients who underwent Roux-en-Y gastric bypass.

This study investigated how vedolizumab affects the immune cells circulating in the blood, particularly focusing on which patients responded well to the therapy.

A new molecular classification for gastrointestinal stromal tumours has uncovered four distinct subtypes and identified a potential tumour suppressor gene.

A recent study highlights a concerning link between the use of GLP-1 receptor agonists (GLP-1RA) and inadequate bowel preparation for colonoscopies.

A recent study from Stanford Medicine highlights both promise and caution surrounding newly approved blood tests for colorectal cancer screening.

Primary sclerosing cholangitis raises colorectal cancer risk even in patients without inflammatory bowel disease, according to new findings presented at ACG 2024.

Research presented at the ACG 2024 has demonstrated high accuracy of small intestinal contrast ultrasonography (SICUS) for assessing small bowel Crohn’s disease

AI-DRIVEN endoscopic ultrasound has demonstrated high accuracy in detecting and differentiating pleomorphic pancreatic lesions, according to new research presented at the American College of Gastroenterology 2024 Annual Meeting.

Research presented at the American College of Gastroenterology (ACG) 2024 Annual Meeting showed that rifaximin monotherapy significantly reduces the risk of recurring overt hepatic encephalopathy

New research presented at the American College of Gastroenterology (ACG) Annual Meeting suggests that GLP-1 receptor agonists (GLP-1RAs) may significantly lower the risk of pancreatic cancer in patients with type 2 diabetes

The American College of Gastroenterology (ACG) has issued a new clinical guideline to help healthcare providers more effectively manage Helicobacter pylori….

A Danish genome-wide association study has identified a genetic marker linked to severe ulcerative colitis, a chronic inflammatory bowel disease with increasing incidence. 

A trial investigated the effects of adding Helicobacter pylori stool antigen testing to colon cancer screening on rates of gastric cancer incidence and mortality. 

Pioneering research presented at UEG Week 2024 has revealed a new treatment approach for Type 2 diabetes that could reduce the need for insulin therapy.  

A study presented at UEGW 2024 is exploring a breakthrough imaging technique aimed at improving treatment outcomes for patients with locally advanced oesophageal cancer.

At UEG Week 2024, researchers showed that TP53 mutations and chromosomal changes improve prediction of oesophageal adenocarcinoma in low-risk Barrett’s oesophagus.

A groundbreaking study presented at UEG Week 2024 has revealed distinct antibody responses in Crohn’s disease and ulcerative colitis apparent years before diagnosis.

Leading health experts at UEG Week 2024 are calling for the implementation of a national, quality-assured colorectal cancer screening programme for individuals aged 45–75.

A new guideline from The American Society of Colon and Rectal Surgeons highlights a personalised, multidisciplinary approach to managing chronic constipation

New research has highlighted a concerning rise in early-onset colorectal cancer cases, accompanied by more aggressive disease and inferior survival.  

A multicentre study shows endoscopic submucosal dissection is a safe, effective treatment for high-risk colorectal neoplasia in patients with inflammatory bowel disease.

Individuals with upper gastrointestinal mucosal damage may be at an increased risk of developing Parkinson’s disease later in life.

New research from DDW 2024 shows older adults with inflammatory bowel disease treated with advanced therapies may face a slightly increased risk of infection.

Metabolic bariatric surgery offers substantial protective benefits for patients with chronic kidney disease, Type 2 diabetes, and obesity, according to new research.

Recent research highlights a significant increase in the risk of Barrett’s esophagus following sleeve gastrectomy, a commonly performed bariatric surgery

A study highlights the potential of intestinal ultrasound as a valuable tool for predicting treatment outcomes in children with moderate-to-severe ulcerative colitis.

Aspirin may help reduce the risk of colorectal cancer among individuals with unhealthy lifestyles, according to recent research.

A study on antimicrobial therapies for patients with acute cholangitis has suggested that a shorter duration of antimicrobial therapy might be sufficient for successful outcomes.

New data has revealed that screening for colorectal cancer using faecal immunochemical tests is significantly associated with a reduction in mortality rates.

Researchers have identified that hypoalbuminemia within the first 24 hours of hospital admission for acute pancreatitis could serve as a significant predictor of adverse outcomes.

Research explores the prevalence of post-infection irritable bowel syndrome and functional dyspepsia after acute gastroenteritis.

Changes in body composition and metabolic markers could enable the early detection of pancreatic ductal adenocarcinoma.

New research has shed light on the potential of the gut microbiota in predicting recurrence of Crohn’s disease following surgical remission.

Use of glucagon-like peptide 1 receptor agonists is associated with an increased risk of aspiration pneumonia in patients undergoing gastrointestinal endoscopy, according to recent research.

Novel research has shed light on the efficacy of proton-pump inhibitors for stress ulcer prophylaxis in critically ill patients undergoing invasive ventilation.

Hematochezia and abdominal pain are the initial symptoms in nearly half of individuals with early-onset colorectal cancer, according to recent research.