Gastroenterology

A study of adults with IBD found faecal calprotectin outperformed other non-invasive biomarkers for distinguishing Crohn’s disease from ulcerative colitis, while albumin-based scores provided moderate assessment of systemic inflammation.

Red blood cell distribution width was linked to IBD activity and may support routine clinical evaluation. Read more.

Nearly half of patients with irritable bowel syndrome experienced weekly abdominal bloating, which was associated with more severe symptoms, greater psychological burden, poorer quality of life, and increased healthcare utilisation.

An AI model improved preoperative risk prediction before gastric cancer surgery, outperforming established clinical scores for postoperative complications and overall survival.

A qualitative study found sexuality discussions in inflammatory bowel disease care were often absent, with patients reporting unmet information needs and identifying trust and clinician competence as essential for meaningful conversations.

Patients with IBD had altered bile acid profiles, reduced TGR5 activation and lower microbial bile acid transformation, which correlated with increased inflammatory activity.

A systematic review of gastric ulcer biopsy strategies found that initial endoscopy and targeted sampling may support diagnostic accuracy, while follow-up decisions should be personalised.

AI demonstrated encouraging potential for nutritional management in IBD, improving dietary assessment, predicting treatment response, and supporting patient education, although larger studies are needed before routine clinical implementation.