Gastroenterology

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Inflammatory Bowel Disease Linked to Reduced TGR5 Activation

August 2026

Patients with IBD had altered bile acid profiles, reduced TGR5 activation and lower microbial bile acid transformation, which correlated with increased inflammatory activity.

New Imaging Technique Shows Promise for Personalised Oesophageal Cancer Treatment – UEG Week 2024

A study presented at UEGW 2024 is exploring a breakthrough imaging technique aimed at improving treatment outcomes for patients with locally advanced oesophageal cancer.

Predicting Progression of Barrett's Oesophagus with Genomic Markers – UEG Week 2024

At UEG Week 2024, researchers showed that TP53 mutations and chromosomal changes improve prediction of oesophageal adenocarcinoma in low-risk Barrett’s oesophagus.

Study Identifies Pre-diagnostic Antibody Signatures in IBD – UEG Week 2024

A groundbreaking study presented at UEG Week 2024 has revealed distinct antibody responses in Crohn’s disease and ulcerative colitis apparent years before diagnosis.

Austrian Experts Call for Nationwide Colorectal Cancer Screening - UEG Week 2024

Leading health experts at UEG Week 2024 are calling for the implementation of a national, quality-assured colorectal cancer screening programme for individuals aged 45–75.

New Guidelines for Management of Chronic Constipation

A new guideline from The American Society of Colon and Rectal Surgeons highlights a personalised, multidisciplinary approach to managing chronic constipation

Rising Early-Onset Colorectal Cancer Cases Linked to Poorer Outcomes

New research has highlighted a concerning rise in early-onset colorectal cancer cases, accompanied by more aggressive disease and inferior survival.

Endoscopic Submucosal Dissection Effective for Colitis-Associated Neoplasia

A multicentre study shows endoscopic submucosal dissection is a safe, effective treatment for high-risk colorectal neoplasia in patients with inflammatory bowel disease.

Upper GI Damage Linked to 76% Higher Parkinson’s Risk

Individuals with upper gastrointestinal mucosal damage may be at an increased risk of developing Parkinson’s disease later in life.

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