Hematology

Thrombocytopenia is generally defined as a platelet count below the lower normal limit, <150×109/L, although many suggest that a cut-off value…

TIM-3 was first discovered in Prof Kuchroo’s laboratory in 2002. This lecture reviewed the history of the discovery of TIM-3, including…

As the second most common haematological malignancy, multiple myeloma (MM), a plasma cell disorder, continues to affect a significant portion of patients with increasing incidence over the past 25 years…

Diffuse large B-cell lymphoma (DLBCL) is an aggressive lymphoma and the most frequent non-Hodgkin lymphoma (NHL) in adults, accounting for 30–40%…

Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) is a positive-sense, single-stranded RNA virus that belongs to the coronavirus family, and it is the seventh in that family known to infect humans…

Paroxysmal nocturnal haemoglobinuria (PNH) is a rare disease of nonmalignant clonal haematopoietic stem cells with an estimated prevalence of 1–16 cases per million, which may be underestimated because of undiagnosed patients…

Although VOC are the hallmark of SCD, a lack of VOC events does not prevent chronic multi-organ damage. Patients with sickle cell anaemia (SCA)…

Ponatinib is indicated for the treatment of adults with chronic myeloid leukaemia (CML) who are resistant to dasatinib or nilotinib, are intolerant…