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AML

Targeted Aptamer Delivery Enhances AML Chemotherapy

January 2026

An optimised OFA/iLRP aptamer forms a DNA nanostructure delivering doxorubicin selectively to AML cells, improving efficacy and reducing toxicity in preclinical models.

AML

Targeted Aptamer Delivery Enhances AML Chemotherapy

An optimised OFA/iLRP aptamer forms a DNA nanostructure delivering doxorubicin selectively to AML cells, improving efficacy and reducing toxicity in preclinical models.

thrombosis

Kinase Regulates Platelet Thrombosis

Researchers have identified serine threonine kinase 10 as a key regulator of platelet function, haemostasis and thromboinflammation.

gene therapy

In Vivo CAR T Shows Promise

At ASH 2025, investigators reported early results from the first-in-human phase 1 inMMyCAR study evaluating KLN-1010, an investigational in vivo gene therapy…

clinical trial

Epcoritamab Shows Promise In Richter Transformation

Among patients treated in the first-line setting, the overall response rate was 57.1%, compared with 38.1% in those treated in the second line or later.

cost effectiveness

Cryopreserved Platelets Underperform In Cardiac Surgery

The study included 202 adults undergoing cardiac surgery at 11 Australian tertiary hospitals between August 2021 and April 2024.

long covid

Genetic Clues Link Clots To Long COVID

New genetic evidence suggests that people with an inherited tendency towards blood clots may be at higher risk of developing long COVID.

thrombosis

Inflammation Markers May Refine Thrombosis Risk

Investigators describe this as the largest study to date linking thromboinflammation biomarkers with thrombosis risk in myeloproliferative neoplasms.

Inflammation Fuels Blood Cancer Progression

Inflammatory molecules circulating in the blood may worsen disease symptoms and points to new opportunities for targeted therapy.

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