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Hepatology
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Neddylation and Hepatic Zonation: Insights Into Liver Metabolism and Diseases
1
Mins
June 2025
The liver exhibits metabolic zonation, with gene expression and metabolic functions distributed across specific zones along the lobule…
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1
Mins
18 Jul 2024
Barriers and Motivators for Implementation of Lifestyle Changes in Metabolic Dysfunction-Associated Steatotic Liver Disease
Patients with metabolic dysfunction-associated steatotic liver disease (MASLD) experience difficulties in complying with required lifestyle…
2
Mins
18 Jul 2024
TGR5 Deficiency in Liver Sinusoidal Endothelial Cells Disrupts Angiocrine Signalling After Hepatectomy
Bile acid (BA) receptors like farnesoid X receptor (FXR) and TGR5 have been implicated in liver regeneration.
7
Mins
18 Jul 2024
EASL 2024 Abstract Highlights
The following highlights spotlight the latest research in hepatology, featuring studies presented at this year’s EASL Congress….
6
Mins
3 Aug 2023
EASL 2023 Abstract Highlights
The following selected abstracts were the pinnacle of those showcased at the European Association for the Study of the Liver (EASL)…
1
Mins
4 Aug 2022
Prescription Event Monitoring of Checkpoint Inhibitor-Induced Liver Injury and Outcomes of Rechallenge: A 10-Year Experience
The definition and severity of checkpoint inhibitor-induced liver injury (ChILI) have been reported using the Common Terminology Criteria for Adverse Events (CTCAE) used in cancer therapy.
2
Mins
4 Aug 2022
Management of Severe, Steroid-Resistant and Steroid-Refractory Hepatotoxicity in Patients Treated with Checkpoint Inhibitor Immunotherapy
Checkpoint inhibitor immunotherapy (ICI) has revolutionised cancer care but is associated with immune-related toxicities, which may require ICI discontinuation and immunosuppressive therapies (IST).
1
Mins
4 Aug 2022
Pre-transplant Changes in Serum Protein Glycosylation Relates to Risk of Hepatocellular Carcinoma Recurrence After Liver Transplantation and Provide a Potential Prognostic Biomarker: A Proof-of-Concept Study
Hepatocellular carcinoma (HCC) recurs after liver transplantation (LT) in approximately 10% of patients. Changes in protein glycosylation have been described during the development of HCC and are associated with progressive disease and early mortality.
1
Mins
5 Aug 2021
Prevalence and Prognostic Value of Cirrhotic Cardiomyopathy as Defined According with the Proposed New Classification
The prevalence and prognostic relevance of cirrhotic cardiomyopathy (CCM), as defined according with the new core criteria proposed in 2019…
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