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Neddylation and Hepatic Zonation: Insights Into Liver Metabolism and Diseases
1
Mins
June 2025
The liver exhibits metabolic zonation, with gene expression and metabolic functions distributed across specific zones along the lobule…
Read more
1
Mins
5 Aug 2021
Referral of Patients with Non-alcoholic Fatty Liver Disease with Significant Fibrosis from Primary Care to Secondary Care in Belgium
Non-alcoholic fatty liver disease (NAFLD) is becoming the most frequent cause of chronic liver disease worldwide. The stage of fibrosis…
1
Mins
5 Aug 2021
MicroRNA-27a-3p Modulates FoxO1 to Induce Tumour-Like Phenotypes in Bile Ducts
The authors analyse the miR landscape of CCA and non-malignant livers to define their roles in orchestrating gene regulation and promoting CCA development.
2
Mins
5 Aug 2021
A MET-Agonistic Antibody Mimicking Hepatocyte Growth Factor Accelerates Liver Regeneration and Improves Survival in Mice Undergoing Carbon Tetrachloride Exposure and Partial Hepatectomy
Small-for-size syndrome (SFSS) is defined by prolonged cholestasis, coagulopathy, and ascites within the first week of liver…
2
Mins
13 Oct 2020
Diagnostic and Prognostic Role of Presepsin in Patients with Cirrhosis and Bacterial Infection
Bacterial infection (BI) is a common event in the natural history of cirrhosis, often requiring hospitalisation due to hepatic and extra-hepatic organ dysfunction..
1
Mins
13 Oct 2020
Fibrosis-4 Score for Assessment of Liver Fibrosis is Useful in General Practice
Early recognition of liver fibrosis will be a challenge that continues in the coming years and should be performed by general practitioners (GP)…
1
Mins
13 Oct 2020
FIB-4 and APRI Scores Revalidation in a Cohort Study of 69,106 Chronic Hepatitis C Patients
Assessment of liver fibrosis is vital for enabling therapeutic decisions and prognostic evaluation of chronic hepatitis…
1
Mins
13 Oct 2020
Progress in Hepatitis C Testing as Part of the Hepatitis C Elimination Programme in Georgia
In April 2015, the country of Georgia, with a high prevalence of hepatitis C virus (HCV) infection (5.4% of the adult population, approximately 150,000 persons), embarked on the world’s first national HCV Elimination programme…
1
Mins
13 Oct 2020
Multivariant Surface Quasispecies in a Hepatitis B Virus Chronically Infected Individual with Concomitant and Continually Positive Surface Antigen and Anti-Hbs Biomarkers
Coexistence of hepatitis B virus (HBV) surface antigen (HBsAg) and antibodies (anti-HBs) can be found in 2.3–5.2% of chronic HBV (CHB) infected individuals…
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