Hepatology

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Nomogram Predicts Long-Term Liver Cancer Risk After Hepatitis C Cure

December 2025

Study shows DAAs and interferon offer similar long-term protection against hepatocellular carcinoma after hepatitis C cure and introduces a nomogram to predict 8-year HCC risk.

New Strategies for Monitoring Liver Fibrosis in Hepatitis C

Among serum biomarkers, the FIB-4 and APRI scores are widely recognised for assessing advanced fibrosis and cirrhosis.

Clinical Trial Validates New MASLD Drug Therapy

This study examined the efficacy and safety of pemafibrate in 360 patients with MASLD and hypertriglyceridaemia.

Non-Invasive Risk Score Predicts Clinical Events in Primary Sclerosing Cholangitis

The study involved 419 patients, aged 18–75, with noncirrhotic PSC, who were randomly assigned to receive either cilofexor or a placebo over 96 weeks.

AI Revolutionises Early Detection of Liver Disease

A new study reveals that AI can identify early-stage metabolic-associated steatotic liver disease using electronic health records.

Neutrophil Extracellular Traps Imbalance Linked to Portal Vein Thrombosis

This study assessed neutrophil extracellular traps and DNase activity in patients with chronic hepatitis B-related decompensated cirrhosis to determine their relationship with PVT.

Targeted Hepatitis C Efforts Show Promising Results in Spain

In Spain, HCV prevalence among people experiencing homelessness has declined significantly, from 7.2% in 2019 to 3.4% in 2023.

New Study Links Fibrosis to Severe MASLD Outcomes

A new study examined the influence of clinical and histologic risk factors on long-term MASLD outcomes in patients confirmed via liver biopsy.

Geographic Disparities in Liver-related Mortality After COVID-19

Rates of liver-related mortality (LRM) in the USA surged by 19.1% from 2018 to 2021, with substantial state-by-state differences…

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