Hepatology

Low donor fasting glucose predicts poorer outcomes after LDLT, highlighting its potential as a prognostic marker.

A Mediterranean diet, rich in whole grains, vegetables, fruits, nuts, and olive oil, is proven to improve liver health by reducing inflammation and fat accumulation.

The tool’s performance was consistent across multiple validation cohorts, though accuracy varied slightly, especially when dealing with different patient populations.

The study’s findings demonstrate that hypovolaemic phlebotomy effectively reduces the need for red blood cell transfusions.

Obesity and diabetes mellitus are widely acknowledged risk factors for the development of steatotic liver diseases, contributing to liver cirrhosis and HCC.

Cirrhosis-associated immune dysfunction heightens infection susceptibility through low-grade systemic inflammation and gut-liver axis alterations.

This study demonstrates that combining vibration-controlled transient elastography with retina scanning offers a practical strategy for identifying individuals with potential liver fibrosis.

These findings suggest that dihydroxyacetone phosphate, along with alanine transaminase, could serve as a valuable non-invasive biomarker for liver fibrosis.

These disruptions may play a pathophysiological role in metabolic dysfunction-associated steatotic liver disease development.

Recent research highlights the discovery of 17 novel loci associated with liver triglycerides and 9 linked to liver inflammation.

Recent studies have highlighted the potential of sodium-glucose cotransporter 2 inhibitors, especially ertugliflozin, in improving outcomes for patients with NAFLD and T2DM.

Frailty has emerged as a therapeutic target in advanced chronic liver disease management, with non-pharmacological interventions showing promise.

Lifestyle modifications, particularly dietary changes, have shown potential in reversing MASLD and steatohepatitis.

A recent clinical trial investigated combining time-restricted feeding and flaxseed for MASLD treatment.

Among serum biomarkers, the FIB-4 and APRI scores are widely recognised for assessing advanced fibrosis and cirrhosis.

This study examined the efficacy and safety of pemafibrate in 360 patients with MASLD and hypertriglyceridaemia.

The study involved 419 patients, aged 18–75, with noncirrhotic PSC, who were randomly assigned to receive either cilofexor or a placebo over 96 weeks.

A new study reveals that AI can identify early-stage metabolic-associated steatotic liver disease using electronic health records.

This study assessed neutrophil extracellular traps and DNase activity in patients with chronic hepatitis B-related decompensated cirrhosis to determine their relationship with PVT.

In Spain, HCV prevalence among people experiencing homelessness has declined significantly, from 7.2% in 2019 to 3.4% in 2023.

A new study examined the influence of clinical and histologic risk factors on long-term MASLD outcomes in patients confirmed via liver biopsy.

Rates of liver-related mortality (LRM) in the USA surged by 19.1% from 2018 to 2021, with substantial state-by-state differences…

A newly developed prognostic model predicts liver cancer risk in patients with hepatitis B without cirrhosis, identifying a nonlinear relationship between viral load and cancer risk

Researchers have revealed that a previous paternal hepatitis B virus infection before conception is associated with an increased risk of congenital heart diseases in offspring.

The Baveno VI criteria, combining liver stiffness and platelet count, offer a noninvasive, cost-effective approach to identifying high-risk varices in patients with cirrhosis

The latest clinical guidelines for diagnosing and managing metabolic dysfunction-associated steatotic liver disease, previously known as NAFLD

A novel automated speech analysis platform has been developed to test for minimal hepatic encephalopathy (HE) and to predict overt HE in patients with cirrhosis. 

Researchers have discovered that the use of glucagon-like peptide 1 receptor agonists in patients with MASLD is linked to a significant reduction in the risk of developing cirrhosis and its complications. 

Declines in serum hepatitis B virus RNA during the first and second year of treatment with nucleoside analogues could be indicators of reduced risk for hepatocellular carcinoma.

A recent study has highlighted a concerning gender disparity in access to liver transplants showing that women on the liver transplant waiting list are less likely to undergo a transplant

A lot has changed within the Progressive Familial Intrahepatic Cholestasis (PFIC) landscape in the last few years. The introduction of…

A new study found that vitamin E supplementation can significantly improve liver health in adults with metabolic dysfunction-associated steatotic liver disease.

A recent study demonstrated an AI model that can accurately predict tacrolimus concentrations and suggest optimal dosing for liver transplant recipients.

Recent studies suggest liver stiffness as the primary indicator for assessing long-term risk after Hepatitis C virus treatment

A new model combining clinical and imaging data effectively predicts the absence of high-risk varices in patients with unresectable hepatocellular carcinoma

A recent study has found that up to 13% of patients with dementia may have undiagnosed cirrhosis, potentially contributing to their cognitive decline.

Liver transplantation significantly improves progression-free and overall survival in patients with unresectable colorectal liver metastasis compared to alternative therapies.

Substituting just one meat-based meal with a vegetarian or vegan alternative has been proven to reduce serum ammonia levels for up to 3 hours in patients with cirrhosis, according to a recent study

Prevalence of hepatocellular carcinoma is rising, particularly in Western countries, research shows that a new treatment modality has the potential to transform care for patients

Transgender adults have been found to suffer from cirrhosis twice as often as cisgender individuals, in a recent study.

New research has revealed a link between diabetes and liver cancer, particularly in patients aged 40-54.

Patients with severe acute-on-chronic liver failure faced higher mortality rates than those without while waiting to receive a liver transplant, according to a recent study

Ablation has been shown to be the most cost-effective treatment for hepatocellular carcinoma in a recently published study.

Women experiencing hot flashes have been found to be more likely to receive a diagnosis of metabolic dysfunction-associated steatotic liver disease.

Weekend admission has been linked to higher mortality risk and post-procedure morbidity amongst patients entering hospital for transjugular intrahepatic portosystemic shunt.

Research highlights the potential of proteomics in early detection of hepatocellular carcinoma and improving diagnostic accuracy.

A recent study has highlighted the importance of physical activity from childhood in preventing liver disease in young adulthood.

New data reveals that bariatric surgery is linked to improvements in clinical outcomes for patients with metabolic dysfunction-associated steatotic liver disease.

New findings demonstrate that the risk of MASLD in early adulthood increased in children born to overweight parents.

A study has revealed a significant link between liver fibrosis and an increased risk of heart failure in the general population

This study aimed to assess this familial risk of CRC and BTC in a large population with PSC

A study has linked liver resection to improved survival outcomes in patients with early liver cancer, finding that the 5-year overall survival rate almost doubled in patients who had undergone LR compared to non-surgical treatments 

Females demonstrate superior survival rates than males following liver transplantation, according to a recent study

A recent study demonstrates hepatocellular carcinoma screening in patients with liver disease and cirrhosis to be associated with improved early-stage tumour detection and survival, persisting after lead-time and length-time bias adjustment.

A new research from the University of Hong Kong has identified bone mineral density as a potentially novel risk factor and early predictor for cirrhosis development. Read more.

Exploring strategies to optimise outcomes for those with HAAA, and assessing both safety and efficacy of HSCT was the goal of an emerging piece of research.

According to research, dietary acid load is significantly associated with cirrhosis-related mortality, and there is further need of investigating underlying mechanisms, as well as establishing optimal DAL levels in patients with cirrhosis.

Screening for osteoporosis is considerably lower in patients with cirrhosis compared with the general population, and less than 25% of those with low bone density are treated, according to a recent study. Read more.

Male hypogonadism is associated with visceral obesity and metabolic syndrome. The present study aims to compare the effects of testosterone treatment with a placebo in treating non-alcoholic fatty liver disease in older hypogonadal males.

New data suggests that the risk of alcoholic relapse in patients with alcohol-related liver disease who underwent liver transplant may be more accurately determined with the help of a new scoring system.

Waitlist outcomes are improved by living donor liver transplantation for high-risk patients with cirrhosis, according to a recent study. This study aimed to assess the impact of access to LDLT in waitlisted patients at highest risk of dropout.

Higher triglyceride levels have been linked with incidence of moderately severe and severe acute pancreatitis in non-alcoholic fatty liver disease. The complications of this hypertriglyceridaemia included organ failure and acute peripancreatic fluid collection.

A spike in the number of hospitalisations for alcohol-related hepatitis occurred during the COVID-19 pandemic. Read more…

According to new research, higher animal protein intake is associated with greater mortality risk in patients with liver cirrhosis…

Stable patients with Child–Pugh A cirrhosis and acute variceal bleeding did not experience different outcomes after antibiotic prophylaxis…

A new study investigates the clinical course of alcohol-related liver disease, considering that 15% of patients experience decompensation…

2.4 million people are living with hepatitis C in the United States, according to federal data, and many don’t know they have the virus…

A study has emerged with interesting risk insights to do with personalisation of treatment in paediatric liver transplantation…

Sought to increase the efficacy of immunotherapy in patients with liver cancer by treatment in combination with adjuvant therapies…

Evidence has further shown a direct correlation between the severity of liver pathology and the level of nerve degeneration…

BILIARY atresia is a rare congenital condition resulting in inflamed and blocked bile ducts. This blockage prevents bile from being…

PATIENTS with acute-on-chronic liver failure (ACLF) typically only have 3 months to live and desperately require a liver transplant for…