Respiratory

A large Phase III trial has found that onradivir, a novel PB2 polymerase inhibitor, significantly shortens recovery time in adults with uncomplicated influenza A.

A structured parenting programme based on acceptance and commitment therapy has shown clinical benefits in managing asthma and ADHD symptoms in children.

New findings support the integration of PET/CT prior to biopsy in patients with intermediate-to-high-risk lung nodules.

A major international trial has assessed whether nasal high-flow oxygen improves outcomes during emergency paediatric intubation.

Next-generation metagenomic sequencing has uncovered key differences in bronchiectasis pathogens and resistance genes across Europe.

Machine learning models using data from digital inhalers can successfully predict COPD exacerbations up to 5 days in advance.

New research suggests that early impairment in mucosal IgA immunity may contribute to the later development of bronchiolitis obliterans syndrome in lung transplant recipients.

Gait parameters in people with COPD progressively worsen with disease severity and differ significantly from healthy older adults.

New research shows lung function peaks earlier in life and declines steadily without plateau, challenging prior assumptions.

A once-daily oral therapy targeting neutrophilic inflammation has shown promise in reducing exacerbations in patients with bronchiectasis.

Including imaging and symptom-based data in COPD diagnosis captures patients with high-risk disease who would otherwise be overlooked by spirometry alone.

Repeated exposure to antibiotics during the perinatal period in very low birth weight preterm infants is associated with impaired lung function by early school age.

A new study identifies airway eosinophilia as a distinct, corticosteroid-responsive subtype of COPD, marked by heightened type 2 inflammation and gene expression changes.

A new Phase III trial has strengthened the evidence supporting cytisinicline as an effective and well-tolerated medication for smoking cessation.

Rare genetic variants and common polygenic risk scores independently influence survival in idiopathic pulmonary fibrosis.

Discover how HSK31858 could transform bronchiectasis treatment by reducing flare-ups – read more about the latest trial results.

New data reveal that acute pulmonary embolism, though rare in children and adolescents, carries a significant risk of death.

Smoking may reduce the risk of developing ulcerative colitis and alleviate disease severity in existing cases.

Statistical analysis shows combined breathing and stretching exercises significantly improve respiratory function and exercise capacity in COPD patients.

Youth using varenicline with brief behavioral support were far more likely to quit vaping than those given placebo or usual care, a new randomized trial finds.

A new study supports the clinical utility of human nasal epithelial cultures as predictive biomarkers for cystic fibrosis CFTR modulator therapy.

Blood eosinophil count and fractional exhaled nitric oxide significantly enhance prognostic assessment of asthma attack risk.

A single dose of the RSVPreF3 OA vaccine offers strong protection against RSV-related lower respiratory tract disease in older adults across three seasons.

Explore how vaping during pregnancy affects maternal health and birth outcomes.

A new 96-week study confirms the long-term safety and sustained efficacy of elexacaftor/tezacaftor/ivacaftor in children with cystic fibrosis aged 6–11 years.

Inpatient pulmonary rehabilitation significantly enhances functional independence in patients with chronic lung disease and extends survival.

A study analysing trends in mortality from occupational chronic respiratory diseases caused by industrial pollutants highlights both progress and ongoing challenges.

Early exposure to ambient ozone in the first 2 years of life is associated with an increased risk of asthma and wheeze in early childhood.

A novel therapeutic vaccine, PRGN-2012, has shown promising results in treating recurrent respiratory papillomatosis.

Obstructive sleep apnoea may increase the risk of developing Parkinson’s, but early treatment with continuous positive airway pressure therapy mitigates this risk.

IL-33 inhibition with tozorakimab may offer clinical benefits in patients with COPD at high risk of exacerbations.

Young adults who use e-cigarettes may experience changes in lung ventilation distribution, potentially indicating early small airway impairment.

Children with above-average BMI trajectories are at increased risk of developing chronic obstructive pulmonary disease later in life.

Molecular residual disease detection may help identify patients with EGFR-mutated NSCLC who could benefit from prolonged adjuvant osimertinib

A new study highlights the significant impact of time of day and season on bronchodilator responsiveness.

A multicentre cohort study found that adherence to annual lung cancer screening declines over time, with lower adherence linked to reduced lung cancer detection rates.

New data confirm that positive airway pressure therapy is associated with a significant reduction in all-cause and cardiovascular mortality in patients with obstructive sleep apnoea.

New research finds that SGLT-2is and GLP-1RAs are associated with a lower risk of COPD exacerbations in patients with Type 2 diabetes and active COPD.

New research has identified a potential causal relationship between lipid metabolism and chronic obstructive pulmonary disease.

Adjuvant corticosteroid therapy reduces 30-day mortality in hospitalised patients with community-acquired pneumonia, but its benefits depend on baseline inflammation levels.

Gut microbiota composition may influence the efficacy and safety of chemo-immunotherapy in advanced non-small cell lung cancer.

A Phase IV trial has demonstrated that dupilumab significantly reduces airway inflammation in patients with uncontrolled, moderate-to-severe type 2 asthma.

Interim findings from the ongoing SOTERIA study suggest that sotatercept provides a favourable long-term safety and efficacy profile for adults with pulmonary arterial hypertension.

A new study assessed asthma risk in children who received antibiotics in the first week of life solely due to maternal indications, eliminating infection-related bias.

A large-scale study suggests that pirfenidone use in patients with idiopathic pulmonary fibrosis may be linked to a lower incidence of lung cancer.

Individuals with impaired lung function trajectories experience a higher burden of respiratory symptoms, including wheeze and phlegm.

The UK IPF Registry has provided new insights into the evolving landscape of idiopathic pulmonary fibrosis management, showing significant shifts in diagnosis and treatment approaches over the last decade.

Lung cancer screening presents a crucial opportunity to address tobacco dependence, as participation is associated with increased motivation to quit smoking.

A nationwide study from South Korea has found a concerning link between obstructive sleep apnea and suicidal behaviors.

Adding genetic risk scores to traditional case-finding methods enhances the detection of undiagnosed COPD, improving early diagnosis and intervention.

A large, multicentre study has demonstrated that robotic-assisted bronchoscopy is both safe and effective for diagnosing small and peripheral lung lesions.

A Phase III trial has shown that rezivertinib offers superior progression-free survival compared to gefitinib as a first-line treatment in EGFR-mutated locally advanced or metastatic non-small-cell lung cancer.

Adults who began smoking before the age of 15 have a significantly higher risk of COPD than those who started later, even when adjusting for smoking history and second-hand smoke exposure.

Extreme temperatures significantly increase morbidity and mortality risks for patients with chronic obstructive pulmonary disease.

A new study across five European countries highlights the impact of RSV on clinical outcomes, healthcare utilisation, and family life.

A large-scale study has revealed a significant association between long-term air pollution exposure and hospital admissions for acute lower respiratory infections in adults.

A new global analysis of lung cancer incidence has uncovered significant geographical and temporal variations in histological subtypes.

New research suggests that elevated circulating cAMP levels could serve as a potential biomarker for asthma.

Vitamin D deficiency is strongly associated with an increased risk of severe acute exacerbations in patients with chronic obstructive pulmonary disease.

New research reveals shifting patterns in lung cancer mortality, with declining smoking rates offset by rising deaths linked to air pollution.

A new qualitative study conducted in France highlights the multiple obstacles patients face before receiving a chronic obstructive pulmonary disease diagnosis.

A systematic review of 33 randomised controlled trials has found that conventional treatments for allergic rhinitis may also improve asthma outcomes in patients with both conditions.

A recent study has uncovered a new connection between genetic risk factors for idiopathic pulmonary fibrosis and the development of post-COVID-19 lung abnormalities.

Xpert MTB/RIF Ultra is able to enhance tuberculosis diagnosis and stratify transmission risk, offering a powerful tool for clinicians.

With traditional bronchial provocation tests often inaccessible in clinical settings, this predictive nomogram offers a practical alternative to assist clinicians.

The Prospector calculator reduces antibiotic use by nearly half in COPD exacerbations, showing promise for safer and more effective patient care.

A high blood NMLR is linked to increased 5-year mortality in COPD patients, highlighting its role as a key prognostic tool.

Home high-flow therapy improves recovery for COPD patients after severe exacerbations, showing potential for better symptom control and reduced readmissions.

A recent outbreak in India identified new hMPV strains, A2.2.1 and A2.2.2, highlighting the evolving threat of paediatric respiratory infections.

Combined valve implantation in the right upper and middle lobes shows promise for severe emphysema, with significant benefits for heterogeneous cases.

1 in 28 people globally will develop lung cancer, with men and wealthy nations at greatest risk, highlighting urgent healthcare disparities.

Changes in muscle-to-fat ratio affect lung function and airflow obstruction, highlighting the importance of body composition in respiratory health.

Rising blood eosinophil counts and high sputum IL-8 levels predict accelerated lung function decline in asthma, highlighting key biomarkers for monitoring.

LCI detects lung function improvements in cystic fibrosis patients on ETI therapy, even when FEV1 changes are minimal, highlighting its clinical value.

Lung cancer deaths among CLRD patients have declined, but older adults, rural areas, and White men remain disproportionately affected.

GLI spirometry criteria reduce COPD misclassification in older smokers, ensuring accurate diagnosis and preventing unnecessary treatments.

New research highlights the predictive power of gut microbiome profiles during acute COVID-19 infection in identifying individuals at risk for Long COVID.

A UK Biobank study links low birth weight to a 21% higher risk of developing COPD later in life. Findings highlight the importance of prenatal care and maternal health in reducing long-term respiratory risks.

A study reveals a strong link between primary ciliary dyskinesia and asthma in children.

Prenatal exposure to common phenols, including butylparaben, has been linked to an increased risk of asthma in children, particularly among boys, according to a large-scale study from Japan.

Living in disadvantaged neighbourhoods worsens lung function and raises mortality risk for idiopathic pulmonary fibrosis patients, especially those with milder disease, according to a new study.

New research highlights how patient-reported asthma symptoms can reveal underlying disease mechanisms, paving the way for personalised treatments.

Doctors should monitor thoracic trauma patients with lateral or posterior rib fractures, displacement, or multiple fractures closely for haemothorax risk, a study recommends.

New insights from a large-scale study reveal how humidity influences respiratory health, offering both protective benefits and potential risks to lung function.

Alcohol’s role in TB risk among diabetics: Moderate drinking may reduce risk, but heavy consumption sharply increases it, particularly for smokers.

Young adults with metabolic syndrome face a significantly increased risk of COPD development, emphasizing the importance of early monitoring and prevention.

Acute exacerbations significantly worsen survival in progressive pulmonary fibrosis, urging a need for targeted management strategies.

Asthma increases the risk of bronchiectasis, with sinusitis and eosinophilic inflammation acting as mediators, according to a new genetic study.

Nicotinamide riboside reduces airway inflammation and boosts NAD+ levels in COPD patients, study shows.

AI-powered urine biomarkers predict COPD exacerbations up to a week before symptoms, paving the way for early intervention.

Machine learning predicts occurrence and mortality of sepsis-associated ARDS with high accuracy, study reveals.

COVID-19 poses significantly higher risks for people with multiple long-term conditions, with increased rates of mortality and severe outcomes.

No difference in mortality found between indwelling pleural catheters and chemical pleurodesis for treating malignant pleural effusions.

Atomized indocyanine green inhalation enhances precision and recovery in paediatric lung surgeries, study finds.

Higher quality of life at admission predicts better outcomes for COPD patients with pneumonia, study shows.

Cumulative corticosteroid dose linked to pneumonia mortality risk in connective tissue disease patients, study finds.

New machine learning model predicts lung perfusion in PE patients from non-contrast CT scans, providing a safer alternative to standard imaging.

Regular physical activity reduces exacerbations in COPD patients using dual bronchodilators, study finds.

New research identifies six clinical phenotypes in young COVID-19 patients, offering insights for personalised paediatric care.

Long-term PAP therapy may boost survival in patients with COPD and OSA, highlighting potential benefits of early diagnosis and proactive respiratory management.

High Flow Nasal Cannula therapy may reduce the need for ventilation in severe COVID-19 cases, improving oxygenation and ICU outcomes.

A Swedish study, using data from the BAMSE birth cohort, has shown that childhood body mass index (BMI) trajectories can have lasting effects on lung health, with certain patterns linked to reduced lung function by early adulthood.

Recent studies and meta-analyses have investigated the impact of PM2.5 on asthma, yet findings remain inconsistent.

A NEW clinical trial has found that the asthma drug montelukast does not shorten the duration of symptoms for mild-to-moderate COVID-19 patients compared to a placebo.

A new study has shown that dual bronchodilator therapy can help reduce exacerbations in patients with chronic obstructive pulmonary disease (COPD), with notable differences in efficacy between current and former smokers.

Detection of SARS-CoV-2 RNA on the floors of healthcare worker-only areas in hospitals is strongly associated with impending COVID-19 outbreaks in hospital wards.

Findings from ERS 2024 show that continuing anticoagulation after the acute phase of COVID-19 significantly reduces the risk of venous thromboembolism in recovering patients.

A new study has found that both indoor and outdoor air pollution significantly worsen respiratory health in patients with COPD

A study shows that brief exposure to ultrafine particles in the air raises the risk of respiratory infections in children.

A new study reveals that people with schizophrenia treated with antipsychotics face higher risks of severe respiratory infections, particularly during the COVID-19 pandemic.

New research shows changes in haemoglobin levels can accurately detect hydrostatic pulmonary oedema in patients with acute dyspnoea

A study has revealed significant differences in influenza and COVID-19 vaccination rates among children receiving long-term ventilation through tracheostomy,

This research has added to the growing body of evidence about the negative long-term effects of vaping.

Research presented at the European Respiratory Society (ERS) Congress has revealed that prolonged exposure to air pollution increases the risk of hospitalisation for respiratory conditions

A recent study utilised AI to detect pulmonary embolism early using only patient records.

A recent study identified significant issues with the suboptimal use of inhalers among hospitalised patients with chronic obstructive pulmonary disease.

A recent study revealed the effectiveness of a tailored, interactive text message program designed to help adolescents quit vaping.

Patients with rheumatoid arthritis-associated interstitial lung disease face a significant risk of severe and often fatal infections, according to a new multicenter prospective study.

A new study found that 92% of patients hospitalised for COVID-19 still have lung lesions two years after discharge.

A study revealed that an AI model can accurately predict lung function metrics such as forced vital capacity and forced expiratory volume in 1 second from chest X-rays.  

A recent study shows many COVID-19 survivors have lasting lung issues and reduced pulmonary function three years post-hospitalization, highlighting the need for ongoing care.

A new study sheds light on the effects of obesity on patients undergoing extracorporeal membrane oxygenation, which is a critical intervention used when all other treatment methods fail.

A recent study suggests that nasal sprays coupled with physical activity and stress management could shorten the duration of respiratory infections, including colds and COVID-19

A RECENT study revealed a significant association between COVID-19 vaccination rates and decreased symptomatic asthma among children.

A recent study revealed that long-term exposure to air pollution during childhood can lead to bronchitis symptoms in adulthood.

A study shows that Indigenous children with bronchiectasis and low cough scores have higher odds of symptom resolution following a 14-day antibiotic treatment for non-severe exacerbations. 

A trial has found that using nasal high-flow oxygen during tubeless upper airway surgery in children does not reduce the frequency of interruptions for rescue oxygenation.

Early lung ultrasonography scores have been linked to future respiratory complications in preterm infants.

A recent study has highlighted the potential of a plant-based diet on reducing the risk of emphysema in young adults with a history of smoking.

Transitioning to race-neutral spirometry reference equations, changes lung function interpretations, potentially impacting treatment for children with chronic lung diseases.

Efficacy, safety, and tolerability of sulthiame (STM) was explored in a new study on the treatment of obstructive sleep apnea (OSA).

Efforts to address the pressing issue of psychological distress among survivors of critical illnesses were explored in a study that optimized a mobile mindfulness intervention app.

New study results highlight the effect of early diagnosis and treatment of undiagnosed asthma or chronic obstructive pulmonary disease.

A recent multicenter study has uncovered critical insights into the risks faced by patients with a history of acute pulmonary embolism during the COVID-19 pandemic.

A recent study investigated whether subtle abnormalities in lung tissue are linked to acute respiratory disease in people with a smoking history

Research has explored whether a plant-centred diet could lower the chances of developing emphysema

According to new study, no association is found between SARS-CoV-2 infection and new asthma diagnoses in children during an 18-month study, highlighting other significant risk factors for asthma.

Research reveals early exposure to nitrogen dioxide air pollution determines a reduced attention capacity in children aged 4–8, especially in males, urging further investigation.

Early exercise training improves exercise capacity and physical function in adults hospitalised for chronic obstructive pulmonary disease, according to a recent combined systemic review and meta-analysis.

Hypertensive disorders in pregnancy don’t increase childhood asthma risk, as per a study of 14,000 mother-child pairs. Only 8.3% of children born to mothers with HDP developed asthma, not significantly different from those without HDP.

Published data has shown the COVID-19 and influenza vaccines to be 50% effective in preventing severe disease, protecting both children and adults against hospitalisation.

Use of a mobile patient lift, combined with a rehabilitation protocol, reduced the time to stand in ventilated patients in the intensive care unit, compared to the protocol alone. Read more.

A recent study has found that there was a significant association between respiratory distress and whether infants had been born to unvaccinated mothers, although none of the babies born had COVID-19 themselves.

According to recent research, adults with chronic obstructive pulmonary disease may be more likely to develop cardiovascular diseases, including coronary heart disease, heart failure, heart attack, and diabetes.

According to a new study, mortality rates due to pulmonary embolism (PE) are higher amongst Black and male patients than those in other demographics. Read more.

According to recent research, augmentation therapy improves survival rates amongst patients with severe ɑ1 antitrypsin deficiency. The findings from this study may benefit those patients with AATD who experience a rapid decline in lung function.

Researchers evaluated patient outcomes following lung transplant surgery for COVID-19-related ARDS and COVID-19-related pulmonary fibrosis…

The risk of asthma exacerbations requiring hospitalisation was found to be higher during warmer temperatures. Read for more…

Wearing a KF80 mask was found not to impact oxygenation and haemodynamic factors in adults with mild to moderate COPD.

A new study investigates former and current smokers to determine if proactive patient education and recruitment impact LDCT screening rates.

RESPIRATORY syncytial virus (RSV) is a major cause of lower respiratory disease and hospitalisation in infants worldwide…

Severe COVID-19 can lead to acute respiratory failure. In patients for whom conventional mechanical ventilatory support has failed, ECMO may be used…

Melatonin, the sleep hormone, potentiated the constriction of the airways, and consequently worsened asthma symptoms at night…

The effect of high-flow oxygen therapy versus conventional oxygen therapy in patients with severe COVID-19 has not been extensively studied

Researchers have speculated that the exposure toxins and fine particles that the first responders were subjected to may eventually suffer…

The study revealed that children who had previous record of severe RSV bronchiolitis during the early stages of life had a significant…

Hopeful researchers have discovered use of the common antibiotic doxycycline, in combination with TB drug treatment, effective in reducing these lung cavities and accelerating markers of lung recovery.

Research conducted at Massachusetts General Hospital (MGH) has uncovered four subtypes of infection, caused by the bronchiolitis respiratory syncytial virus (RSV), one of which is linked with higher asthma risk.  

IN 2020, lung cancer was the second most common cancer and the leading cause of death from cancer among both males and females in the USA. Screening…

CORONAVIRUS disease (COVID-19) has been linked to the development of neurological symptoms and complications in patients who become ill with the…

LACTOBACILLUS has been shown to provide a barrier against Streptococcus pneumoniae colonisation in mice infected with the influenza A virus, providing new insights on how bacteria protect against invading pathogens.

TARGETING endothelial cells in patients with coronavirus disease (COVID-19) with severe lung disease may provide a novel approach to restoring normal lung function, according to a recent study from Stony Brook University, Stony Brook, New York, USA.

Researchers have identified key markers that could help predict which patients are at increased risk of developing severe COVID-19…

But according to a new study, patients seriously ill with COVID-19 could be at risk of developing permanent nerve damage from being placed in the prone…

ONE IN FOUR patients with chronic obstructive pulmonary disease (COPD) have never smoked and the reasons behind this have long evaded researchers

COVID-19 has been shown to significantly affect the lungs. To understand how the immune cells of the lung respond to viral infection, researchers…

ARTIFICIAL intelligence could be used as a crucial tool for clear, objective assessment of lung disease to aid radiologists in what has been a measured…

I am not a fatalist, I do not believe things happen for a reason, but I do believe we can find reason in the things that happen…

An incredible global effort is underway by companies and scientists digging deep to find a vaccine for Covid-19…

IVERMECTIN, an antiparasitic drug that is in use around the world, has shown to kill the SARS-CoV-2 virus within 48 hours…

Love in the Time of Cholera, the widely known 1985 novel by one of my favourite authors, Gabriel García Márquez, primarily details the affairs of three main…

RAPID diagnosis of COVID-19 is critical to reduce the spread of the virus to the public and healthcare providers around them.

PULMONARY fibrosis, a life-threatening disease caused by the damaging and scarring of lung tissue, currently has limited treatment options…

THE VIRUS associated to coronavirus disease 2019 (COVID-19), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…

INFECTION with the novel China betacoronavirus (2019-nCoV) was detected using medical imaging techniques such as CT scans…

A PREDICTION model for tuberculosis (TB) in people living with HIV has been suggested by the results of a recent study. Researchers from the Department…

The NEUROTRANSMITTER dopamine has been shown, in the latest research, to play a key role in development of the sympathetic nerves of the mouse lung in…

INHALABLE nanoparticles have been shown success in animal models to treat lung cancer. The study, carried out by a team supervised by Professor Dawen Zhao…

ACUTE respiratory distress syndrome (ARDS) can now be detected, quickly and accurately, by a breath analyser that has been developed by a team…

MILD ASTHMA in children can be managed when symptoms occur by the use of two inhalers: a steroid and bronchodilator…

Lung cancer has a relatively poor prognosis, killing nearly 1.8 million people worldwide each year. A common procedure for improving remission rates is…

Targeting the mid-to-late gestation period of fetal development is an attractive means of averting deadly, and potentially irreversible, pathological…

VITAMIN D could provide vital new treatment options for patients with multi-drug resistant tuberculosis (TB) according to the results of a recent clinical..

The need for a revaluation of chronic obstructive pulmonary disease (COPD) diagnostic practices has been highlighted by a study investigating the records…

One of the latest additions to the panoply of smoking devices is the heat-not-burn (HNB) devices. These are positioned as a hybrid of traditional…

Air pollution, caused by cars and other pollutants, has long been linked to asthma attacks. A new study, conducted at the Milken Institute School of…

Drug-induced interstitial lung disease (DIILD) causes breathing difficulties, pulmonary fibrosis, and inflammation. It is diagnosed in 4.1–12.4 million…

The European Medical Journal has published the latest edition of the EMJ Respiratory eJournal, which includes a comprehensive review…

A project in which people deemed to be at risk of poor lung health are invited to attend a routine lung health check has been highly…

Antibiotic resistance, a topic reviewed in one of EMG’s latest blog posts, is an issue of growing concern. As bacterial resistance extends to even the…

The legalisation of cannabis for medical use has induced heated debate both in the political and medical spheres. Recent news of a young epileptic…

Screening for obstructive sleep apnoea (OSA) in older people could help prevent dementia, according to new research published by the European…