Rheumatology

Researchers from the OsteoLaus cohort have developed a machine learning model to predict fragility fractures in postmenopausal women using bone and body composition data.

A study from the Hertfordshire Cohort has found that older adults with obesity and radiographic knee osteoarthritis experience greater pain and impaired function compared to their non-obese peers.

New data suggest that elderly individuals with type 2 diabetes who initiate GLP-1 receptor agonist therapy may face a slightly higher risk of bone fractures compared to those using other common diabetes

A new study shows that artificial intelligence could be a valuable ally in identifying osteoporotic vertebral compression fractures (VCFs), a common yet underdiagnosed complication of aging.

A new study reveals the C-reactive protein-albumin-lymphocyte (CALLY) index is a strong predictor of long-term survival in rheumatoid arthritis patients.

Transitional and CD21⁻ PD-1⁺ B cells identified at diagnosis were linked to better treatment outcomes in early rheumatoid arthritis, according to a spin-off analysis of the NORD-STAR trial.

A study finds that caffeine intake improves endothelial function in systemic lupus erythematosus by enhancing cell survival and reducing inflammation.

New findings show that eosinophilic granulomatosis with polyangiitis (EGPA) patients in remission may safely reduce mepolizumab dosage, potentially easing long-term treatment burden.

A new study highlights anti-M3R antibodies as markers of a more aggressive clinical phenotype in systemic sclerosis, particularly affecting gastrointestinal health.

Patients with rheumatoid arthritis who stopped TNF inhibitors experienced fewer flares and treatment failures on methotrexate-tacrolimus therapy compared to methotrexate alone, with no major safety concerns.

New long-term study data suggest that patients with rheumatoid arthritis who achieve sustained disease control on baricitinib 4 mg may successfully taper to 2 mg, with the majority maintaining low disease activity or recapturing control if needed.

Asthma may raise the risk of developing osteoarthritis, with socially isolated or lonely individuals facing even greater susceptibility, according to a new large-scale cohort study.

A new study shows that even during the Omicron era, patients with systemic autoimmune rheumatic diseases face significant risks of hospitalisation due to COVID-19, particularly if unvaccinated or on immunosuppressive therapies.

Researchers introduce a new Genetic Progression Score (GPS) that enhances prediction of autoimmune disease progression by integrating biobank and case-control genetic data.

KL-6 and hSP-D levels at baseline, and changes in KL-6 over time, are strongly associated with progression of RA-associated interstitial lung disease, according to a Korean prospective cohort study.

A Danish study finds that symptom interpretation and beliefs about treatment impact how quickly patients with early rheumatoid arthritis seek medical help.

New research from the tREACH cohort reveals that female patients with rheumatoid arthritis experience higher disease activity and functional limitations compared to males, even under treat-to-target care.

Initiating steroid treatment before specialist evaluation may obscure the clinical signs of polymyalgia rheumatica, reducing diagnostic accuracy.

A new study reveals high rates of depression and fibromyalgia in Jordanian women with lupus, calling for an integrated approach to managing both physical and psychological aspects of the disease.

A decade-long study has found that each year of infliximab use is linked to an 11% lower risk of cervical spine deformity in RA patients, potentially extending the known benefits of the drug beyond peripheral joints.

A new study suggests that arthritis, particularly osteoarthritis, may increase the risk of overactive bladder.

Patients with systemic sclerosis (SSc) face a higher risk of death from lung, gynecological cancers, and T/NK lineage lymphomas, according to a new study.

A recent study has found that gastrointestinal symptoms and depression are strongly linked to higher disease activity in spondyloarthritis patients.

A recent study highlights the role of inflammation in osteoporosis, identifying AISI, SIRI, and SII as key inflammatory markers associated with lower bone mineral density (BMD) in older adults.

While patients with rheumatoid arthritis have a lower overall cancer incidence rate, they face higher post-cancer mortality.

ChatGPT4 may be a game-changer for patient education in lupus, with a new study showing its responses match or even exceed those of specialists in key areas like patient satisfaction and empathy.

Obesity significantly diminishes the effectiveness of urate-lowering therapy in male gout patients, according to a new study. Only 38.9% of obese patients achieved target serum urate levels compared to 63.8% of normal-weight patients, highlighting the need for integrated weight management in gout treatment.

A Mediterranean diet combined with exercise significantly improves muscle function, pain, and inflammation in females with rheumatoid arthritis.

A new predictive model accurately assesses arthritis risk using common health indicators, offering potential for early prevention.

Study reveals ANCA positivity in 22.4% of patients with ILD, with implications on survival.

New research suggests that patients with obesity who undergo knee or hip replacements can lower their risk of revision surgery by losing weight after the procedure with anti-obesity medications.

A large-scale analysis of five clinical trials of belimumab has found that normalizing serology enhances the effectiveness of treat-to-target strategies in SLE.