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Gastroenterology
2 Mins
1st December 2016

Surgical Transanal Resection of Early Rectal Tumours

Rates of early rectal cancer detection are on the increase due to screening programmes and wider public awareness. Most rectal cancer is treated by…
Gastroenterology
3 Mins
1st December 2016

Curative Options for Hepatitis B and D

The hepatitis B virus (HBV) is a small, partially double-stranded DNA virus that causes acute and chronic hepatitis in humans. About 240 million people…
Gastroenterology
2 Mins
1st December 2016

Feasibility, Safety, and Efficacy of Knife-assisted Resection of Rectal Polyps Extending to the Dentate Line: How Low Can You Go?

Rectal polyps extending to the dentate line (RPDL) pose a technical challenge to endoscopic resection due to the narrow lumen and more.
Gastroenterology
1 Mins
1st December 2016

Enhanced Diagnostic Performance of Symptom-Based Criteria for Irritable Bowel Syndrome by History and Diagnostic Evaluation

As clinicians, we are encouraged to use symptom-based diagnostic criteria to diagnose irritable bowel syndrome (IBS). The Rome III criteria have been…
Gastroenterology
2 Mins
1st December 2016

A Randomised Controlled Trial Comparing Air Insufflation, Water Immersion, and Water Exchange for Adenoma Detection in Screening Colonoscopy Patients

Low adenoma detection rate (ADR, proportion of patients with at least one adenoma found in the colon) is correlated with the risk of post-colonoscopy…
Gastroenterology
1 Mins
1st December 2016

Pancreatic Cancer: The Role of Cancer-Associated Fibroblasts in Drug Metabolism

Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant disease with a 5-year survival rate of only 8%. Within the USA, PDAC is expected to become…
Gastroenterology
2 Mins
1st December 2016

Endoscopic Mucosal Resection for Large Sessile Colonic Polyps (≥2 cm) Over a 9-Year Period: A Single-Centre Experience and Analysis of Changes Over Time in a University Teaching Hospital

Endoscopic mucosal resection (EMR) has become the standard technique for resection of large sessile and flat colonic polyps. We aimed to assess the…
Gastroenterology
2 Mins
1st December 2016

Unsupervised Transcriptomics-Based Clustering of Ulcerative Colitis Patients Reveals Marked Heterogeneity that Relates to Anti-Tumour Necrosis Factor Treatment Response

Heterogeneity within inflammatory bowel disease cohorts is often cited as the biggest challenge to reliably studying the clinical efficacy of therapeutics.