US Archives - Page 139 of 243 - European Medical Journal

Lack of Rigorous Clinical Data Risks Efficacy Decline in Influenza Vaccines

High-quality clinical data is essential to maintaining trust in influenza vaccination programs, especially as the global death toll from seasonal flu approaches 700,000 annually, disproportionately affecting older adults.

Global Psoriatic Arthritis Guidelines Reveal Gaps

A new comparative analysis of international guidelines for psoriatic arthritis (PsA) management reveals key divergences in treatment strategies across leading rheumatology societies, underscoring ongoing challenges in global consensus despite shared therapeutic goals.

New Mortality Risk Model for Severe Drug Reaction

A new international study has developed and validated prognostic models using novel inflammatory markers to predict in-hospital mortality in patients with drug reaction with eosinophilia and systemic symptoms (DRESS), a rare but life-threatening hypersensitivity reaction.

Is Faster Cancer Treatment Finally Within Reach? Understanding Subcutaneous Immunotherapy

Subcutaneous (SC) delivery of immunotherapies for solid tumors has emerged as a potentially transformative approach to cancer treatment, promising comparable clinical efficacy to intravenous (IV) therapies while significantly reducing treatment time and burden on healthcare systems.

Real-World Trial Validates AI for EGFR Mutation Testing in Lung Cancer

An artificial intelligence tool trained on digital pathology slides has demonstrated clinical-grade accuracy for detecting EGFR mutations in lung adenocarcinoma and significantly reduced reliance on molecular testing, according to results from a large-scale real-world deployment study.

Artificial Sweetener Alters Vascular Function in the Brain

The non-nutritive sweetener erythritol, commonly found in sugar-free beverages, may impair brain microvascular endothelial cell function by increasing oxidative stress and disrupting nitric oxide (NO) signaling, according to new in vitro findings.

Updates in HR+ Advanced Breast Cancer

The therapeutic landscape for hormone receptor-positive (HR+) advanced breast cancer (BC) is moving from generalized endocrine therapies…

Enhancing Cancer Care Through Vaccines

Patients with cancer often have a compromised immune system, which places them at an increased risk of infection that can extend beyond…

Advances in HER2-Mutant NSCLC

Mutations in HER2, also known as ERBB2, represent a distinct molecular subset of NSCLC, occurring in approximately 2–4% of cases, and are…

Targeting DLL3 in Rare Neuroendocrine Carcinoma

EpNECs are considered rare and are often associated with a poor prognosis, with up to 85% of patients presenting with advanced…