Current Status And Future Perspectives On Drug-Eluting Bioresorbable Coronary Scaffolds: Will The Paradigm Of PCI Shift? - European Medical Journal
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Current Status And Future Perspectives On Drug-Eluting Bioresorbable Coronary Scaffolds: Will The Paradigm Of PCI Shift?

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Authors:
*Alfonso Ielasi, Maurizio Tespili
Disclosure:

No potential conflict of interest.

Received:
16.01.14
Accepted:
28.02.14
Citation
EMJ Int Cardiol. ;1[1]:81-90.

Each article is made available under the terms of the Creative Commons Attribution-Non Commercial 4.0 License.

Abstract

Despite improvements in stent platform, polymer, and drug elution, the permanent metallic stents have significant limitations as they distort vessel physiology, predispose to late thrombosis, and may preclude surgical revascularisation. Bioresorbable scaffold (BRS) technology has evolved over the last few years to overcome these drawbacks. Actually, different BRS are either available or under clinical and preclinical investigation. However, the use of BRS has largely been restricted to patients recruited into clinical trials with a relatively small number of ‘real-world’ patients treated with these devices. Here, we highlight the potentialities of these devices, describe the evidence from the recent clinical trials, and discuss the potential advantages as well as challenges that this novel technology may face in routine clinical practice.

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