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Unrepaired TOF with Pulmonary Atresia and MAPCA in Pregnancy
7
Mins
October 2025
Tetralogy of Fallot (TOF) is one of the most common forms of cyanotic congenital heart disease, characterised by…
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11
Mins
17 Oct 2019
Chemokines: A Potential Therapeutic Target for the Stabilisation of Vulnerable Plaque
In the late 20th century, lipid lowering medications appeared to be the answer for coronary heart disease. However, despite reductions in mortality…
9
Mins
17 Oct 2019
Circulating Cardiac Biomarkers in Heart Failure: A Critical Link to Biomarker-Guided Therapy
A contemporary conceptual framework that was proposed to distinguish between different chronic heart failure (HF) patients has highlighted varying…
10
Mins
6 Sep 2019
A Clinical Review of Ventricular Arrhythmias in Patients with Congestive Heart Failure
Pump failure and sudden cardiac death are the leading causes of death in heart failure patients; sudden cardiac death accounts for 30–50% of deaths…
9
Mins
14 Mar 2019
Inflammation and Thrombosis in Coronary Atherosclerosis: Pathophysiologic Mechanisms and Clinical Correlations
The importance of inflammation and thrombosis in the pathophysiology of atherosclerosis was debated in the 19th century by two prominent pathologists…
10
Mins
11 Oct 2018
Guidelines, Clinical Evidence, and Real-Life Practice: How to Find Your Way in Managing Hypercholesterolaemia
Prof Masana presented evidence that low-density lipoprotein (LDL) cholesterol is a causal factor for atherosclerosis and that cardiovascular disease (CVD…
4
Mins
11 Oct 2018
Reversal of Apixaban and Rivaroxaban Anticoagulation by Andexanet Alfa in ANNEXA-A and ANNEXA-R as Assessed by Non-Tissue Factor-Initiated Thrombin Generation Independent of Tissue Factor Pathway Inhibitor
Andexanet alfa is a modified factor Xa (FXa) drug designed to bind and sequester FXa inhibitors and thus reverse anticoagulation…
10
Mins
11 Oct 2018
Editor’s Pick: Contemporary Use of Intracoronary Imaging in Percutaneous Coronary Intervention
For >50 years, coronary angiography has been the gold standard for the assessment of coronary anatomy; however, as an isolated technique to guide the…
8
Mins
11 Oct 2018
A Comparison of Different Doses of Dexmedetomidine for Myocardial Protection in Percutaneous Coronary Interventional Patients
Acute myocardial infarction (MI) is a major cause of death and disability worldwide. Myocardial injury in acute MI is due to both ischaemic as well…
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