Dermatology

Patients with hidradenitis suppurativa face a significantly higher risk of developing new-onset depression and anxiety, according to a large Danish population-based study.

Daily moisturising may prevent infant eczema, even in low-risk babies, offering a practical approach for early skin care.

Discover a study highlighting the improved effectiveness of combining light-based therapy with tranexamic acid for treating facial redness.

Results showed the secretome-HA sponge improved skin hydration, reduced transepidermal water loss, increased skin elasticity.

Results from the 12-month double-blind, placebo-controlled trial revealed that the vaccinated group consistently experienced greater reductions in AK lesions than the control group.

The study examined flare patterns reported in 2022 and correlated them with patient-reported severity measures recorded in 2023.

These vaccines work by activating the immune system to recognise and attack tumour cells, while also creating immune memory for long-term protection.

Results demonstrated a clear association between elevated emotional distress and poorer TIL therapy outcomes.

Gene expression analysis also revealed that increased Myc-related gene expression correlated with poorer outcomes.

Discover a study highlighting how tapinarof cream 1% delivers rapid, clinically significant itch relief in children and adults with atopic dermatitis.

Both treatments resulted in significant improvement in inflammatory acne lesions; however, IPL yielded better overall outcomes.

This post hoc analysis included data from 25 randomised clinical trials, assessing over five years of IXE exposure in patients with psoriasis.

As HS remains underdiagnosed and undertreated, findings such as these could help support more informed, patient-specific therapeutic decisions moving forward.

A recent study has demonstrated that deep learning models can enhance diagnostic accuracy in differentiating these pigmented lesions.

Discover a study revealing how vitamin C supports skin regeneration by promoting keratinocyte proliferation through epigenetic DNA demethylation.

The study highlights how HR pathway alterations, which affect roughly a fifth to a third of melanomas, may offer an opportunity for targeted treatment.

VISIBLE Cohort B represents a landmark study in psoriasis research, being the only scalp psoriasis trial exclusively including individuals with skin of colour.

Researchers developed a self-injection assistance device, allowing patients to administer triamcinolone themselves under medical guidance.

Given dupilumab’s well-documented benefits in controlling moderate to severe AD, clinicians are advised to weigh this potential risk carefully against its therapeutic advantages.

The bidirectional relationship between psoriasis and MetS was supported by evidence showing that metabolic disturbances can also exacerbate psoriasis symptoms.

Discover a study where two investigators, using new TikTok accounts registered as 13-year-olds, collected and analysed the videos through the platform’s “For You” tab.

Following surgery, 97.2% of patients experienced a reduction in psoriasis severity to mild levels or complete resolution.

The findings indicate that children with HS are significantly more likely to suffer from a range of both physical and mental health conditions.

The model integrates four key types of imagery: total-body photographs, standard clinical photos, dermoscopic close-ups, and dermatopathology slides.

Compared to patients from the highest SES quintile, those in the lowest quintile had over three times the odds of being diagnosed with hidradenitis suppurativa.

A new global observational study has revealed a continued rise in skin cancer burden among older populations, particularly in high-income countries.

The results revealed that central adiposity, fat concentrated around the waist and abdomen, had the strongest link to psoriasis.

The findings highlight that abobotulinum toxin A and prabotulinum toxin A demonstrated the quickest onset of action.

In this study, researchers examined three international cohorts of patients with moderate-to-severe psoriasis undergoing biologic therapy.

Pure atopic dermatitis patients had a significantly higher prevalence of cardiovascular disease compared to those with atopic comorbidities

Young adults (18–29 years) had the highest UV exposure and sunburn rates, and were least likely to use protective clothing.

Interestingly, UVB exposure and topical application of cis-UCA led to changes in the skin’s microbial composition.

Mental health issues such as anxiety and depression are common comorbidities in people with atopic dermatitis.

The results demonstrated significantly greater improvement in the ivarmacitinib groups compared to placebo.

Discover a study that evaluated the effectiveness of hyperbaric oxygen therapy for radiation-induced dermatitis.

A study has shed new light on a novel approach to managing acne vulgaris, highlighting the efficacy of an oral nutraceutical.

Safety concerns surrounding certain therapies in children often lead to suboptimal management of atopic dermatitis.

Restoring the skin barrier is key in managing and potentially preventing atopic dermatitis.

An increasingly studied adjunctive therapy is Hyaluronic Acid, known for its hydrating, regenerative, and anti-inflammatory properties.

Beyond clinical outcomes, the simultaneous approach offered additional benefits: reduced overall treatment time and higher patient satisfaction.

This study underlines the urgent need for cost-conscious strategies in the management of plaque psoriasis.

Results revealed that the group using partially myristoylated carboxymethyl chitosan emulsion experienced a significantly greater reduction in EASI scores.

Discover a study with has highlighted the potential of a novel silk elastin-based sponge as an effective wound treatment.

A recent clinical trial has compared the effectiveness of IL-17 and IL-23 biologics in treating moderate to severe plaque psoriasis.

Discover a recent study that indicates that autonomous total body photography could be a valuable tool in dermatological settings.

The study’s findings suggest that targeting the epidermal innate immune system could improve long-term treatment outcomes.

Recent research has highlighted the role of neutrophil extracellular traps in inflammatory diseases.

The study assessed the risk of hospitalisation for serious infections based on different categories of systemic medications.

The results indicated that 3D total-body photography reduced the number of melanoma excisions compared to controls.

From a therapeutic perspective, these findings advocate for a more tailored approach to treatment.

Spesolimab, a monoclonal antibody targeting the interleukin (IL)-36 receptor, has been approved as the first GPP-specific therapy.

The findings of this study suggest that both 70% and 100% TCA achieve similar overall results.

Results suggest that standard HPV vaccination may offer a novel approach to actinic keratosis management.

Overall, the study’s findings support the use of Amjevita and Imraldi as equally effective alternatives to Humira.

A national cohort study found that veterans in the most disadvantaged areas had a higher risk of being diagnosed with thicker melanomas.

The study also highlighted the psychological burden of hyperhidrosis, linking the condition to increased anxiety, depression, and impaired quality of life.

A new study investigates the combination of nivolumab and hypofractionated radiotherapy in advanced melanoma.

Recent research highlights the role of gut microbiota in atopic dermatitis pathogenesis.

Although the Skindex-29 assessment indicated an improvement in emotional well-being after the first cycle, there were no significant or lasting changes.

The DermSat-7 is a self-administered instrument designed to evaluate patient satisfaction with psoriasis treatments over a 14-day recall period.

These findings highlight the effectiveness of low-dose oral minoxidil as an alternative to topical minoxidil.

This study aimed to compare the effects of antimicrobial–corticosteroid combination therapy with corticosteroid monotherapy.

The findings suggest that topical spironolactone 5% gel is an effective and well-tolerated treatment for acne vulgaris.

Findings suggest that probiotics’ ability to reduce the risk of atopic eczema may not depend on significant changes in gut microbiota.

Patients initially receiving placebo experienced notable improvement after switching to tildrakizumab.

Recent findings indicate that c-Rel expression is upregulated in psoriatic skin lesions and decreases following treatment.

Leveraging TLR7/8 agonists in combination with systemic IFN-I represents a promising strategy for treating melanoma.

After five years, the probability of remaining free from treatment failure was 77.8% for patients who underwent superficial curettage.

While numerous pharmacological treatments for atopic dermatitis exist, there is a scarcity of effective nonpharmacological interventions.

A targeted rituximab infusion at 6 months, based on relapse predictors, significantly reduced pemphigus recurrence at one year.

Neoadjuvant T-VEC achieves resectability in 50% of difficult-to-treat BCC cases, improving outcomes without extensive reconstructive surgery.

Studies have shown that psoriasis patients exhibit elevated intestinal permeability, correlating with gastrointestinal discomfort.

Diabetes was investigated in five studies, with only one demonstrating a correlation between the condition and higher hospital readmission rates.

A recent study examined the scalp microbiome in Black women diagnosed with central centrifugal cicatricial alopecia, compared with matched healthy individuals.

A recent qualitative study has provided valuable insights into the experiences of Latine patients in the US living with moderate to severe psoriasis.

A gut-derived bacterial compound significantly slows vitiligo progression in mice, offering new hope for treatment and repigmentation.

Potent corticosteroids provide superior symptom relief for moderate atopic dermatitis flare-ups in children, enhancing primary care management.

This study aimed to evaluate whether novel biologics pose different risks of major adverse cardiovascular events compared with tumour necrosis factor inhibitors.

A recent multicentre, randomised clinical trial aimed to evaluate the efficacy and safety of combining baricitinib, with narrowband UV-B phototherapy in adults with severe, active, nonsegmental vitiligo.

Individuals with Down syndrome exhibit a hyperactive immune system marked by increased interferon signalling and cytokine production.

Recent research has investigated the efficacy of excimer light and topical methotrexate 1% hydrogel in managing scalp psoriasis.

A study leveraging social media platforms explored topical steroid withdrawal among individuals with atopic dermatitis.

The study revealed that 22.5% of patients experienced acne relapse, and 8.2% required isotretinoin retrial.

A comprehensive study of 2,657 patients assessed the relationship between chronic inflammatory disease comorbidities and alopecia areata characteristics.

Combining fractional CO2 laser with topical dutasteride improves androgenic alopecia outcomes compared to laser treatment alone.

The visible nature of dermatological symptoms exacerbates their impact, often leading to stigma, social withdrawal, and psychological distress, including anxiety and depression.

Genetic testing reveals key variants in palmoplantar keratoderma, aiding diagnosis and subtype differentiation.

COVID-19 increases the long-term risk of autoimmune disorders, especially in severe cases and unvaccinated individuals.