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Neddylation and Hepatic Zonation: Insights Into Liver Metabolism and Diseases
1
Mins
June 2025
The liver exhibits metabolic zonation, with gene expression and metabolic functions distributed across specific zones along the lobule…
Read more
2
Mins
8 Jun 2017
Magnetic Resonance Imaging of Diffuse Liver Diseases
Virtual liver biopsy (VLB) can be considered a multicomponent imaging biomarker able to provide fundamental information on the presence, distribution…
1
Mins
8 Jun 2017
Adenosine 2A Receptor Stimulation Prevents the Multiple Processes That Lead to Hepatic 'Immuno-Lipotoxicity' in Mice Fed a Methionine Choline-Deficient Diet and Blocks Non-Alcoholic Steatohepatitis Development
Non-alcoholic fatty liver disease (NAFLD) is a benign condition, but in ~20% of patients it can evolve into non-alcoholic steatohepatitis (NASH) with…
1
Mins
8 Jun 2017
A New Screening Strategy for Varices by Liver and Spleen Stiffness Measurements in Cirrhotic Patients: A Randomised Controlled Trial
Variceal screening with upper endoscopy is recommended in cirrhotic patients but unfortunately is costly, uncomfortable to patients, and has low uptake.
2
Mins
8 Jun 2017
Predicting Severe Liver Disease in the General Population: Abdominal Obesity, Insulin Resistance, Diabetes, Cholesterol, and Alcohol
Liver disease is the 13th leading cause of death worldwide, and hepatocellular carcinoma is the 2nd leading cause of cancer death. Finland has one of the…
1
Mins
8 Jun 2017
Japanese Guidelines and Real-World Data on the Management of Hepatitis C
The guideline committee of the Japan Society of Hepatology (JSH) have promptly updated the treatment guideline for the hepatitis C virus (HCV) after…
2
Mins
8 Jun 2017
What is the Role of Ursodeoxycholic Acid for the Future Management of Patients with Primary Sclerosing Cholangitis in the Clinic and in Trials?
Primary sclerosing cholangitis (PSC) is a rare, progressive, cholestatic, immune-mediated hepatobiliary disease. It is characterised by inflammation…
2
Mins
8 Jun 2017
Hepatitis E Virus Infection and Acute Non-Traumatic Neurological Injury
Hepatitis E virus (HEV) is endemic in many developed countries, with seroprevalence rates ranging from 4.7% in Scotland to 31.1% in France. Cases are…
2
Mins
8 Jun 2017
Clinical Hepatocyte Cell Therapy: Challenges and Opportunities
The clinical application of hepatocyte transplants to treat patients with liver disease extends back to the early 1990s. Hepatocyte transplants are…
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