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EMJ
29 Dec 2013

Towards a Standardised Method to Acquire and Store Liver Samples and Guidelines to Improve Quality Control and Exchange of Relative Expression Data

The current ‘state-of-the-art’ molecular techniques are extremely sensitive and consequently prone to false results. Even more so than in the past…
EMJ
29 Dec 2013

Management of Hepatitis B Virus Infection in Liver Transplant Recipients

Hepatitis B virus (HBV)-related liver disease is a common indication for liver transplantation (LT) in Asian countries. When left untreated, the overall…
EMJ
29 Dec 2013

IL28B Polymorphisms in Interferon-Treated Patients with Chronic Hepatitis B

Pegylated interferon (Peg-IFN) may achieve a sustained off-treatment response in 20-30% of the patients with chronic hepatitis B (CHB).
EMJ
29 Dec 2013

Cellular Consequences of Z Alpha-1 Antitrypsin Accumulation and Prospects for Therapy

The Z variant (Glu342Lys) of α1-antitrypsin polymerises and accumulates in the hepatocyte endoplasmic reticulum predisposing to neonatal hepatitis…
EMJ
29 Dec 2013

Acute-On-Chronic Liver Failure: Applying the PIRO Concept

Acute-on-chronic liver failure (ACLF), a clinical syndrome associated with a dismal prognosis, occurs acutely in previously stable cirrhotic patients.
EMJ
29 Dec 2013

Adrenal Insufficiency (AI) in Cirrhosis

Adrenal dysfunction or insufficiency (AI) in cirrhosis, also described as hepato-adrenal syndrome, is an only recently recognised entity.
EMJ
29 Dec 2013

Hepatic Encephalopathy: A Paradigm Shift

The most recent understanding of the pathogenesis of hepatic encephalopathy (HE) is that heterogeneous precipitating factors cause a low-grade cerebral…
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