Articles

Metabolic acidosis is characterised by a primary decrease in the serum bicarbonate concentration, a secondary decrease in the arterial partial pressure of CO­2, and a reduction in blood pH. Metabolic acidosis, acute or chronic, may have deleterious effects on cellular function and cause increased morbidity and mortality.

Dr Imran Ahmad. Consultant Anaesthetist and Deputy Clinical Director for Theatres, Anaesthetics and Peri-operative Medicine, Guy’s and St Thomas’ NHS Foundation Trust, UK; President, Difficult Airway Society (DAS); Honorary Clinical Lecturer, King’s College London, UK.

Ben Challacombe |Consultant Urological Surgeon, Guy’s and St Thomas’ NHS Foundation Trust and King’s College London, UK. Having spent over 10 years in your current role with Guy’s and St Thomas’, what initially sparked your interest in urology and has pushed you to reach your established position today?

EMJ spoke to Samin Sharma about the Eternal Heart Care Centre (EHCC), percutaneous coronary intervention, and advances in the field.

Measurement of fluid biomarkers of neurodegeneration is an emerging approach offering improved diagnostic accuracy of neuropsychiatric conditions, particularly for atypical presentations. This article reports a case where the diagnosis of delirium with dementia was revised based on biomarker analysis, enabling treatment of a primary mood disorder with resolution of recurrent disabling psychiatric symptoms.

A 38-year-old male with a right cervical mass, fever, and sweating was admitted to the authors’ hospital in 2020. The patient had no weight loss or asthenia.

Peter Gill | Staff Paediatrician and Associate Scientist, The Hospital for Sick Children and SickKids Research Institute, Toronto, Canada; Assistant Professor, Department of Paediatrics and Institute of Health Policy, Management and Evaluation, University of Toronto, Canada

Damian Roland | Head of Service, Children’s Emergency Department, Leicester Royal Infirmary, UK; Honorary Professor, Population Health Sciences, University of Leicester, UK