Dermatology

A nationwide Danish study found that estrogen-containing therapy was associated with increased odds of porphyria cutanea tarda, with an association observed for oral but not non-oral administration.

Multisite mucous membrane pemphigoid: only 45% achieved complete remission, with oral and ocular disease limiting treatment success.

Lebrikizumab maintained deep skin responses and sustained itch improvements for up to three years in early responders with moderate-to-severe atopic dermatitis, with infrequent flares among stable responders.

Treatment-emergent skin toxic effects during first-line enfortumab vedotin plus pembrolizumab were associated with longer overall survival.

An Australian cohort study evaluating six melanoma risk prediction models found moderate discrimination and variable calibration, with most models underestimating observed melanoma cases.

Auricular acupressure for rosacea improved treatment success and vascular measures in a randomised, sham-controlled trial.

Lichen planus cancer risk was elevated for oral and genital cancers in a Danish cohort, although absolute risks remained low.

An international study found that CLIPI scores distinguished progression risk and treatment response in advanced mycosis fungoides and Sézary syndrome, improving prognostic discrimination beyond baseline clinical stage.