Dermatology

A phase III trial found no clinical benefit from efgartigimod plus prednisone over prednisone alone in moderate-to-severe pemphigus.

Research suggests CD1a-autoreactive T cells may sense chronic skin barrier compromise through altered sphingomyelin activity, linking lipid processing with immune activation in atopic dermatitis.

MMS showed no significant difference in five-year CSCC recurrence versus standard excision, while producing smaller surgical defects.

A Chinese multicentre cohort identified 11 causative genes and distinct genotype–phenotype patterns in non-syndromic hereditary hypotrichosis.

IL-19 atopic dermatitis activity was linked to epidermal barrier dysfunction and amplified type 2 inflammation.

A phase 2 trial found that a single intravenous dose of recibokibart rapidly improved pustulation and overall disease severity in acute GPP flares.

A cohort study found pleomorphic dermal sarcoma shared key genetic features with metastatic cutaneous squamous cell carcinoma but differed from soft-tissue sarcoma.

A post-hoc analysis found that proxy reports of clinician-diagnosed atopic dermatitis performed well for remotely identifying cases in children younger than two. Meta description: Remote atopic dermatitis diagnosis