Neurology

Global data reveal persistent burden from headache disorders, highlighting urgent clinical and public health priorities for prevention and management.

New evidence suggests paternal valproate use may increase child neurodevelopmental risk, prompting new clinical guidance considerations.

A new study shows that long sustained-attention tasks detect fatigue in people with multiple sclerosis far more effectively than short cognitive tests.

A major UK study of 309,000 adults links better sleep quality to a lower risk of developing migraines, partly explained by healthier cholesterol levels.

By demonstrating that targeted molecular editing can reverse memory loss in ageing brains, this research opens an entirely new direction for therapies.

Study reveals doxycycline may lower schizophrenia risk in adolescents, offering new hope for mental health prevention.

Study finds traumatic spinal cord injury linked to higher long-term risks of chronic illness, including heart disease and diabetes.

Study reveals cladribine reduces disability progression in Treatment-Naive Relapsing-Remitting MS more so than sphingosine-1-phosphate receptor modulators.

Researchers find early signs of brain damage in rugby players through advanced imaging and biomarker analysis.

Researchers detect hidden signs of awareness in ICU patients using fNIRS brain imaging, reshaping understanding of consciousness.

New research links Obstructive Sleep Apnea to brain microbleeds, suggesting early intervention could reduce neurological and stroke risks.

New research links music for dementia prevention to lower cognitive decline risk and better long-term brain health.

Anxiety research in teenagers shows EEG-fMRI fusion can predict future anxiety, paving the way for personalised prevention strategies.

A UK study reveals how weight and mental illness are linked, with emphasis on long-term weight gain and limited access to care.

AI-driven nerve stimulation shows significant improvement in essential tremor symptoms, offering a noninvasive treatment alternative.

New research finds women with hyperemesis gravidarum face higher risks of depression before and after pregnancy.

The KARMA-Dep 2 trial finds ketamine for depression no more effective than placebo in treating hospitalised patients with major depression.

New research links antipsychotic medication in dementia hospice patients to increased mortality risk.

New genetic research explores whether lowering cholesterol can protect against dementia across major populations.

A GENFI study reveals a new MRI method detects early frontotemporal dementia changes before symptoms or brain shrinkage.

A geographical analysis shows ALS and MS follow nearly identical patterns, suggesting shared environmental influences behind both diseases.

A new trial shows that hearing their mother’s voice helps premature babies build neural connections essential for language.

New analysis reveals a link between posttreatment amyloid levels and clinical improvement in Alzheimer’s treatment outcomes.

ALS risk is heightened in the first two years after traumatic brain injury but does not remain elevated long term, suggesting reverse causality.

Almost a third of severe Long COVID patients are diagnosed with POTS, especially middle-aged women, impacting recovery and quality of life.

This study supports HD-tDCS as a safe, fast-acting, and effective non-invasive option for depression treatment.

Trial shows candesartan cuts migraine days and is well tolerated. Read more to learn about this promising prevention therapy.

Study links sugary drink intake and depression to gut microbiome changes, especially in women, suggesting new prevention strategies.

Skin-to-skin contact in hospital helps very preterm infants develop stronger brain pathways for stress and emotions.

Adaptive brain stimulation proves safe and effective for Parkinson, reducing side effects while maintaining long-term symptom control.

Large-scale observational and genetic analyses reveal that alcohol consumption is associated with higher dementia risk. Genetic evidence contradicts protective effects of light drinking.

A Phase I/II trial of AMT-130 gene therapy slowed Huntington’s disease progression by 75% over 36 months, showing biomarker and functional benefits.

Dementia prevention must start in childhood, with new evidence linking lifelong social adversity to brain decline and disease risk.

Half of critically ill encephalitis patients face poor outcomes within months, but recovery varies by cause. Keep reading to learn more.

International study links seizure-related breathing interruptions to epilepsy mortality risk, paving the way for improved monitoring and prevention.

Updated global criteria standardise diagnosis of vascular cognitive impairment and dementia, incorporating biomarker guidance and preclinical assessment.

Cooler bedrooms and brighter daytimes shown to promote better sleep and wellbeing in people living with dementia, new study reveals.

SLIT2 protein in eye and blood linked to early cognitive decline, paving the way for new dementia tests.

Childhood cognitive skills linked to lower mortality risk, but adversity may weaken these protective effects into adulthood.

Air pollution may drive Lewy body dementia by triggering toxic brain protein clumps, new research shows.

Single-dose MM120 provides fast, lasting anxiety relief in generalised anxiety disorder, paving the way for new treatments.

Frequent use of artificial sweeteners may speed up memory loss and thinking decline, particularly for those with diabetes.

AI speech analysis detects neurological disorders with over 90 percent accuracy, promising rapid non-invasive screening worldwide.

A large cohort study using data from the UK Biobank has found that metabolic syndrome is associated with an increased risk of developing Parkinson’s disease, particularly in individuals with a high genetic predisposition.

Medical cannabis linked to better sleep, mood, and life quality in insomnia patients over 18 months, real-world study finds.

Focal epilepsy study shows most patients need over a year and multiple medications to gain seizure control.

Prenatal pesticide exposure linked to brain abnormalities and motor deficits in children, new MRI study shows.

Over half of chronic pain patients discontinue medical cannabis within a year, highlighting need for individualised care.

Dopamine changes link to psychotic symptoms, suggesting new treatment avenues for mood disorders with psychosis.

A multidimensional framework revolutionises traumatic brain injury characterisation, offering more personalised and accurate care.

Men with dementia show higher mortality and hospitalisation rates than women, according to major US Medicare study.

Tongue coating analysis reveals microbial and metabolic markers to aid Parkinson’s disease diagnosis.

Health care visits rise years before multiple sclerosis diagnosis, suggesting earlier signs and opportunities for intervention.

Prenatal maternal depression alters brain connectivity patterns in children through adolescence, new large-cohort study reveals.

Herpes virus exposure linked to faster rises in dementia biomarkers for ageing women, shedding light on infection’s role.

Study of over one million children finds no link between aluminium in vaccines and autism or chronic illnesses.

Pregnancy does not raise the risk of recurrent artery dissection or stroke in women with prior CeAD, new study finds.

Understand how MRI sign accurately identifies Parkinson’s in complex cases, offering a radiation-free alternative to SPECT scans.

Discover why older adults with insomnia face greater depression risk from inflammation. Keep reading for clinical insights and guidance.

Parental genetics and kidney function partly shape blood-based biomarkers for dementia, underscoring the need for careful interpretation.

Semaglutide and tirzepatide lower risks of dementia, stroke, and death in type 2 diabetes and obesity, new study shows.

Learn how metformin may enhance cognitive function in schizophrenia by regulating energy metabolism and brain connectivity.

Music therapy shows promise for reducing distress in patients with dementia on NHS wards, supporting safer, more compassionate care.

Erythritol at common dietary levels impairs brain endothelial cell function, raising new concerns for cerebrovascular health.

Learn how low-dose IL-2 shows early promise in safely modulating Alzheimer’s biomarkers and immune response.

Ambroxol increased enzyme levels in Parkinson’s dementia patients, but showed no cognitive benefit in a year-long trial.

Longer sleep after concussion is linked to more symptoms and slower recovery in young people, new research finds.

Covert cerebrovascular disease may significantly raise fall risk in older adults, even in the absence of symptoms.

Learn how prenatal tobacco alters teen brain development and behaviour, discover key findings and implications. Read more!

Despite the setback, hope remains, with 138 dementia drugs currently in trials, experts say more effective, safer options may soon emerge.

Blood biomarker sNfL predicts MS relapses up to a year in advance, offering new hope for earlier intervention.

AI tool GPT-4o boosts diagnosis accuracy for nerve disorders, helping non-specialists match expert recommendations in real cases.

Frequent nightmares accelerate ageing and triple risk of early death, highlighting a new target for preventive healthcare.

A routine blood test for insulin resistance can predict which Alzheimer’s patients are at risk of rapid cognitive decline.

Nighttime heart rate variability may reveal hidden risks for stroke, depression, and dementia, years before symptoms appear.

Oral bacteria migrating to the gut may drive dementia risk in Parkinson’s, offering new hope for early intervention.

A large meta-analysis suggests TMS improves clinical outcomes in OCD and nicotine dependence, but the role of symptom provocation needs further study.

Healthy lifestyle choices could reduce the risk of stroke, dementia, and late-life depression in individuals with biologically shorter telomeres.

New research reveals that depression following stroke has a significant long-term impact on survival, recovery, and quality of life.

Find out how depression raises dementia risk throughout life – keep reading for the latest research findings.

Dementia diagnoses decline, but more Americans are living longer with the disease and need ongoing support.

Major study finds no early clinical differences between autistic boys and girls at the time of first diagnosis.

Experimental drug jacifusen shows promise for rare ALS, with some patients experiencing unprecedented recovery and stabilisation.

The study found no significant link between the presence of acute infarction and fatigue.

Long-term consumption of ultraprocessed foods is associated with an increased risk of multiple nonmotor symptoms that often precede a Parkinson’s disease diagnosis.

Aspirin cessation fails to cut cSDH recurrence post-surgery, trial reveals.

Baseline brain circuit activity predicts who benefits most from MDMA, paving the way for personalised psychiatric treatments.

Find out how maternal hypertension affects preterm infant brain development and why early intervention is crucial – read more.

Discover how psilocybin therapy could transform Parkinson’s care – read more about this promising pilot trial and future directions.

Autologous haematopoietic stem cell transplantation outperforms alemtuzumab and ocrelizumab in relapse prevention for relapsing MS.

Tricyclic antidepressants and non-invasive neuromodulation techniques lead updated neuropathic pain treatment guidelines.

Alzheimer’s risk factors impact cognition as early as age 24, study reveals.

Young adults face a low but notable risk of epilepsy after stroke, with risk factors well-predicted by current scores.

Blood pressure control over 48 months cuts dementia risk by 15% in a large clinical trial.

Research reveals that APOE4 and early dementia elevate late-onset epilepsy risk in cognitive decline.

Uncinate fasciculus lesion burden is tied to severe anxiety in MS patients, study reveals.