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Critical Management of Neurocysticercosis with Hydrocephalus
6
Mins
June 2025
Neurocysticercosis, a parasitic brain infection caused by the larvae of Taenia solium that leads to cysts in the central nervous system…
Read more
6
Mins
27 Jun 2025
Critical Management of Neurocysticercosis with Hydrocephalus
Neurocysticercosis, a parasitic brain infection caused by the larvae of Taenia solium that leads to cysts in the central nervous system…
4
Mins
26 Jun 2025
Mitigating the Treatment Gap in Drug-Resistant Epilepsy
For this article, EMJ conducted an interview with Ahmed Abdelmoity, Professor and Director, Division of Neurology, Children’s Mercy…
5
Mins
5 Jun 2025
CAR-T Cell Therapy in MS
CAR T Therapy: The NEX-T Frontier in MS, a BMS non-promotional symposium at ECTRIMS 2024, presents a thought-provoking view on the potential role of CAR-T cell therapy in Multiple Sclerosis. 𝗙𝗼𝗿 𝗛𝗲𝗮𝗹𝘁𝗵𝗰𝗮𝗿𝗲 𝗣𝗿𝗼𝗳𝗲𝘀𝘀𝗶𝗼𝗻𝗮𝗹𝘀𝗼𝗻𝗹𝘆. 𝗧𝗵𝗶𝘀 𝘀𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺 𝘄𝗮𝘀 𝗼𝗿𝗴𝗮𝗻𝗶𝘀𝗲𝗱 𝗮𝗻𝗱 𝗳𝘂𝗻𝗱𝗲𝗱 𝗯𝘆 𝗕𝗿𝗶𝘀𝘁𝗼𝗹 𝗠𝘆𝗲𝗿𝘀 𝗦𝗾𝘂𝗶𝗯𝗯. 𝗕𝗠𝗦 𝗺𝗲𝗱𝗶𝗰𝗶𝗻𝗲𝘀 𝗮𝗻𝗱/𝗼𝗿 𝗽𝗿𝗼𝗱𝘂𝗰𝘁 𝗶𝗻𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗼𝗻 𝗺𝗮𝘆 𝗯𝗲 𝗱𝗶𝘀𝗰𝘂𝘀𝘀𝗲𝗱. (IMM-GB-2400302) | Date of Prep: June 2025
13
Mins
31 May 2025
Navigating treatment switch in LOPD
This symposium, ‘A case-based approach to navigating treatment switch in late-onset Pompe Disease (LOPD)’, was held at the 21st…
6
Mins
29 May 2025
Blood-Based Neurology Biomarkers
The landscape of neurology biomarkers has evolved significantly in recent years, affording new clinical insights that are helping to…
7
Mins
22 May 2025
FcRn Blockers in gMG A Case-Study
Generalised myasthenia gravis (gMG) is a rare and chronic IgG-mediated autoimmune neuromuscular disease that causes fluctuating and…
5
Mins
21 May 2025
Perampanel as Early Add-On
Leading neurologist discusses evidence from a real-world post hoc analysis of the PERMIT study supporting perampanel as early add-on…
8
Mins
2 May 2025
Clinical Advancements in Becker Muscular Dystrophy
Becker is a serious, progressive muscular dystrophy that presents predominantly in males due to an X-linked…
9
Mins
14 Apr 2025
Intravenous Anti-CGRP Therapy for the Treatment of Migraine
This promotional advertorial article has been fully commissioned by Lundbeck Ltd. UK PI & AER info is available within the article…
7
Mins
13 Mar 2025
New Horizons for Metachromatic Leukodystrophy
This article summarises an Orchard Therapeutic-sponsored symposium titled ‘New horizons for metachromatic leukodystrophy – with the advent…
7
Mins
13 Mar 2025
Does the Gut Microbiome Influence the Efficacy of Psychiatric Drugs?
Altered gut microbiome profiles correlate with anxiety and depression in humans, and work in animal models has identified specific…
5
Mins
13 Mar 2025
Systemic Health Impact of Leaky Barriers in the Oral-Gut-Brain Axis
The human body is a holistic system, interconnected by the circulatory, nervous, lymphatic, endocrine, and immune systems that facilitate…
5
Mins
13 Mar 2025
Infliximab-Induced Multifocal Motor Neuropathy
Multifocal motor neuropathy (MMN) is a rare immune-mediated disorder characterised by progressive, asymmetric muscle weakness…
2
Mins
11 Feb 2025
Targeting Tau in Early Alzheimer’s Disease
Phase 2 randomised controlled trial (RCT) of BMS-986446, a monoclonal antibody targeting the tau microtubule binding region (MTBR)…
5
Mins
24 Jan 2025
Early Intervention in MS
A satellite symposium titled ‘Transforming MS Care: Early Intervention and Sustained Safety’ held at the 40th Congress of the European…
8
Mins
16 Jan 2025
Long-Term Patient Outcomes: The Role of Sustained Treatment Efficacy in Myasthenia Gravis
There have been great advances in the field of generalised myasthenia gravis (gMG) in recent years, but many patients remain dissatisfied…
9
Mins
12 Dec 2024
The CORE-VNS study: Design and Interim Analysis
This article summarises a LivaNova-sponsored symposium entitled ‘The Power of Real-World Evidence with CORE-VNS’, delivered on 7th…
31 Oct 2024
Tackling Infectious Diseases
This interactive article summarises key discussions from GSK sponsored symposia that took place during the ESCMID Global Congress 2024, held from 27–30th April 2024 in Barcelona, Spain.
4 Oct 2024
The Unspeakable Disease: A Tale of Two Siblings
The deficiency of arylsulfatase A due to the mutations in the ARSA gene is the cause of a rare inherited lysosomal storage disease…
12 Sep 2024
Early Recognition, Diagnosis, and Treatment of Friedreich Ataxia
6
Mins
27 Aug 2024
Understanding Developmental and Epileptic Encephalopathies
Developmental and epileptic encephalopathy (DEE) refers to a collection of rare and severe epilepsies that feature both seizures and…
8
Mins
13 Aug 2024
Reimagining Myasthenia Gravis Care
Myasthenia gravis (MG) is an autoimmune disease caused by autoantibodies targeting proteins on the neuromuscular junction. Around 85%…
8
Mins
13 Aug 2024
Update on Daridorexant for Insomnia
During this symposium, held at the 10th Congress of the European Academy of Neurology (EAN), speakers highlighted that chronic insomnia…
2
Mins
13 Aug 2024
Nipocalimab and gMG: Top Line Results from the Phase III Vivacity-MG3 Study
Nipocalimab, a high-affinity, fully human, aglycosylated, effectorless, monoclonal antibody, has been developed as an add-on treatment…
5
Mins
13 Aug 2024
Diagnosing Synucleinopathies
Parkinson’s disease (PD) is the second-most common neurodegenerative disease after Alzheimer’s disease (AD), with an estimated…
9
Mins
13 Aug 2024
Patterns of Laryngeal Changes on Clinical Application of Mechanical Insufflation-Exsufflation
Individuals with neuromuscular diseases (NMD), where deterioration in bulbar function coexists with respiratory muscle weakness, are at…
10
Mins
13 Aug 2024
A Rare Case of Cervical Intramedullary Spinal Cord Abscess
The occurrence of intramedullary spinal cord abscesses (ISCA) is rare, a phenomenon attributable to a confluence of physiological and…
5
Mins
13 Aug 2024
Bromocriptine in the Management of Central Hyperthermia
Fever is a common medical issue encountered in neurorehabilitation units. The most common cause of fever is infection; the common…
7
Mins
1 Aug 2024
Interview: Kailash Bhatia
I completed my neurology training in Mumbai, India. At the end of my general medical degree, I was influenced by a top-rate neurologist…
6
Mins
19 Jul 2024
Roundtable Interview: Olivier Rascol and Wassilios Meissner
When I started as a neurologist and a clinical pharmacologist, there were a lot of interesting developments in movement disorders…
9
Mins
13 Jun 2024
Balancing Exercise and Contraction-induced Muscle Injury in Muscular Dystrophies
The rare diseases Duchenne and Becker are X-linked recessive neuromuscular disorders.1 They are characterised by progressive…
8
Mins
19 Mar 2024
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: Masterclass Event Summary
A masterclass initiated, organised, and funded by UCB, sought to advance understanding and expertise of myelin oligodendrocyte…
8
Mins
15 Mar 2024
Impact of Non-Seizure Symptoms in Dravet Syndrome and Lennox-Gastaut Syndrome
Non-seizure symptoms in Dravet and Lennox-Gastaut syndromes can affect speech, gait, appetite, mood, development, and sleep and impact…
8
Mins
14 Dec 2023
Spasticity Following Acute Stroke
Many patients experience impairment following a stroke, including motor or cognitive impairment, urinary incontinence, dysphagia…
8
Mins
14 Dec 2023
Tackling Becker Muscular Dystrophy
First described by German physician Peter Emil Becker in the 1950s, Becker is an X-linked genetic recessive disorder. Like Duchenne…
7
Mins
20 Nov 2023
A Review of Oral Fixed-Dose Sodium Phenylbutyrate and Ursodoxicoltaurine in People with Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is estimated to affect approximately 300,000 individuals worldwide…
11
Mins
4 Oct 2023
Lennox–Gastaut Syndrome: Challenges in Diagnosis – Interviews with Two Key Opinion Leaders
Lennox–Gastaut syndrome (LGS) is a severe childhood-onset epilepsy syndrome that can be challenging to identify due to its heterogeneous and..
13
Mins
14 Sep 2023
The Unspeakable Disease: A Tale of Two Siblings
The deficiency of arylsulfatase A due to the mutations in the ARSA gene is the cause of a rare inherited lysosomal storage disease…
6
Mins
14 Sep 2023
Assessment of Post-Traumatic Stress Disorder in Patients Who Recovered from COVID-19
It is essential to address psychological health, particularly post-traumatic stress disorder (PTSD), among patients who have recovered from…
11
Mins
15 Aug 2023
Focal Onset Seizures: New Treatment Options in The Clinical Practice
Carreño began by discussing the spectrum of uncontrolled epilepsies. They stressed that uncontrolled epilepsy does not necessarily…
15 Aug 2023
Retracted: A Spotlight on Friedreich Ataxia: Optimising the Patient Journey from Diagnosis to Disease Management
This article has now been retracted and a retraction statement has been published.
6
Mins
15 Aug 2023
Development of the Clinical Myotonia Rating Scale and a Mexiletine Prescribing and Monitoring Algorithm for Patients with Non-Dystrophic Myotonia
In the rare neuromuscular disorders classed as NDM, muscle stiffness (myotonia) is the major symptom and is defined by a delayed muscle…
8
Mins
15 Aug 2023
Mitochondrial DNA Maintenance Disorders: Impact of Impaired Deoxynucleoside Triphosphates Metabolism
The maintenance of mitochondrial DNA (mtDNA) is dependent upon several nuclear gene-encoded proteins including enzymes forming the…
4
Mins
15 Aug 2023
Interview: Hugh Selsick
My science degrees were pivotal in fuelling my passions and setting out my career path. During my undergraduate physiology degree…
7
Mins
15 Aug 2023
Cerebrotendinous Xanthomatosis: A Clinical Series Illustrating the Radiological Findings
Cerebrotendinous xanthomatosis (CTX) is a unique disease with an autosomal recessive inheritance, occurring due to the accumulation…
7
Mins
15 Aug 2023
Study for Assessment of Mental Health in Survivors of COVID-19
COVID-19 infection was first reported in December 2019 in Wuhan, China, as a pneumonia outbreak presenting with fever…
6
Mins
15 Aug 2023
Lymphoma of Nervous System or the Great Imitator in Neurology
Primary and secondary lymphoma of the central nervous system (CNS) is a rare case of non-Hodgkin lymphoma. The World…
7
Mins
13 Jul 2023
Isolated Sacral Tuberculosis: A Rare Case Report and
Literature Review
Tuberculosis (TB) is an infectious disease caused by the transmission of Mycobacterium tuberculosis bacillary complex…
8
Mins
3 May 2023
Editor's Pick: Orthostatic Hypotension and Concomitant Paraneoplastic Syndromes: A Case Report
Paraneoplastic autonomic neuropathy is a syndrome with an unclear aetiology and wide array of symptoms. Some studies have identified a strong autoimmune component in the development of paraneoplastic autonomic neuropathy, though some aetiologies are non-immune in nature.
2
Mins
2 Mar 2023
From CoNFLict to Confidence: Solving a Diagnostic Dilemma Using Neurofilament Light – A Case Report
Measurement of fluid biomarkers of neurodegeneration is an emerging approach offering improved diagnostic accuracy of neuropsychiatric conditions, particularly for atypical presentations. This article reports a case where the diagnosis of delirium with dementia was revised based on biomarker analysis, enabling treatment of a primary mood disorder with resolution of recurrent disabling psychiatric symptoms.
8
Mins
20 Feb 2023
Benzodiazepines in Dementia: Review of Clinical Evidence
In the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), Alzheimer’s disease (AD [named after the German psychiatrist and neuropathologist, Alois Alzheimer, who first described it]), is considered as a major or mild neuro-cognitive disorder…
5
Mins
17 Feb 2023
Hearts are NOT Made to Be Broken: Expert Opinion on Amyloid Light-Chain Cardiac Amyloidosis
Amyloid light-chain (AL) amyloidosis is a rare systemic disease caused by plasma cell dyscrasia. These plasma cells produce excess Ig light chains, which can misfold, aggregate, and deposit in tissues, resulting in toxicity and organ dysfunction. The heart is among the most commonly affected organs and cardiac involvement is associated with significantly worse outcomes.
11
Mins
31 Jan 2023
The Efficacy and Safety of SARS-CoV-2 Vaccinations in People with Multiple Sclerosis
While people with multiple sclerosis (MS) are not more likely to contract COVID-19, the incidences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and COVID-19-related complications may be higher for people with MS who have comorbidities or who are taking certain disease modifying therapies (DMT).
7
Mins
8 Dec 2022
Tailoring Motor Fluctuation Treatment: Beyond Levodopa Dose Adjustment
Fox emphasised that PD is one of the fastest-growing neurological disorders. Disability and deaths related to it have more than doubled from 1990–2015. Its prevalence is expected to grow exponentially by 2040, affecting approximately 12.9 million individuals worldwide.
10
Mins
8 Dec 2022
The Pathophysiological Relationship Between Migraine and SARS-CoV-2 Infection
People with migraine, and individuals with other neurological conditions, have suffered in multiple aspects during the COVID-19 pandemic. This paper will discuss the factors that impacted the neurology department.
13
Mins
8 Dec 2022
Mexiletine in the Treatment of Non-dystrophic Myotonia: Interviews with Six Medical Experts
NDM includes a group of rare hereditary neuromuscular disorders caused by mutations in the genes that encode sodium or chloride muscle channels.1 Myotonia is the hallmark symptom of NDM and presents as muscle stiffness, often associated with pain, fatigue, and weakness, which can limit function.
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