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Immunological pathways and strategies in SLE
10
Mins
March 2026
Systemic lupus erythematosus (SLE) is characterised by type I interferon signalling, immune complex formation, complement activation, and…
Read more
6
Mins
15 Jul 2021
Interview: Karen Walker-Bone
Karen Walker-Bone | Professor and Honorary Consultant in Occupational Rheumatology, University of Southampton; Director, Arthritis Research…
10
Mins
15 Jul 2021
Editor’s Pick: Management of Pregnancy in Rheumatic Disease
Many patients with rheumatic diseases (RMD) are diagnosed during their childbearing years.1 Historically, females with RMDs were advised to avoid pregnancy due to potential risk to both mother and fetus.
11
Mins
15 Jul 2021
Clinical Manifestations and Diagnosis of Behçet’s Syndrome
Behçet’s syndrome (BS) was first described by Hulusi Behçet in 1931, as a definite clinical entity, the ‘triple symptom complex’, based on three prominent signs: relapsing oral apthae, genital ulcerations, and iritis.
10
Mins
15 Jul 2021
Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management
Axial spondyloarthritis (axSpA) is a chronic inflammatory condition that predominantly affects the sacroiliac joints and spine. It is a…
14
Mins
15 Jul 2021
Treat to Target in Spondyloarthritis: Myth or Reality?
A treat-to-target (T2T) strategy is a treatment plan in which the clinician treats the patient aggressively enough to reach and maintain explicitly specified and sequentially measured goals, such as remission, low disease activity, or absence of disability.
12
Mins
15 Jul 2021
A Worthwhile Measurement of Early Vigilance and Therapeutic Monitor in Axial Spondyloarthritis:
To examine clinical application of QSS, the authors developed a search strategy of QSS using a literature review through database of MEDLINE, Embase (Ovid), CINAHL (EBSCOhost), HaPI (Ovid), Cochrane Review (Ovid), and citation mining.
11
Mins
15 Jul 2021
The Interplay of Genes with the Gut Microbiota in the Aetiopathogenesis of Spondyloarthropathies
The spondyloarthropathies (SpA) are a spectrum of inter-related conditions that include axial spondyloarthritis (AxSpA), (also known as ankylosing spondylitis; AS), non-radiographic axial spondyloarthritis, peripheral spondyloathritis (pSpA), reactive arthritis (ReA), and enteropathic arthritis associated with Crohn’s disease (CD).
9
Mins
17 Jun 2021
Prevalence of Scoliosis in Hypermobile Ehlers-Danlos Syndrome
The main purpose of this study was to evaluate the prevalence, form, and severity of scoliosis in a population of adults meeting the 2017 criteria for hypermobile Ehlers-Danlos syndrome (hEDS).
6
Mins
24 May 2021
Musculoskeletal Brucellosis in Adults in the United Arab Emirates: A Retrospective Study
Brucellosis is a zoonotic infection, historically known as Maltese fever, caused by aerobic Gram-negative coccobacilli, which was first identified by Sir…
7
Mins
22 Mar 2021
Performance of Different Criteria Sets for Inflammatory Back Pain in Radiographic
It is important to recognise inflammatory back pain (IBP) for early diagnosis of ankylosing spondylitis (AS). The aims of this study were to develop….
10
Mins
19 Feb 2021
Diagnosis, Treatment Management, and the Genetic Basis of Psoriasis, Psoriatic Arthritis, and Spondyloarthritis
Psoriatic arthritis (PsA) is an inflammatory condition of the joints and the areas where tendons and ligaments connect with bone…
9
Mins
10 Dec 2020
Optimising Response to Advanced Therapies in Rheumatoid Arthritis - Using Prehabilitation to Improve Success?
This article explores applying the principle of prehabilitation to patients with rheumatoid arthritis prior to starting advanced therapies, including…
10
Mins
10 Dec 2020
Longitudinal Characterisation of the Gastrointestinal Tract Microbiome in Systemic Sclerosis
To evaluate changes in microbial composition and the evolution of gastrointestinal tract (GIT) symptoms in systemic sclerosis (SSc).
5
Mins
17 Sep 2020
Superficial Ulcerating Rheumatoid Necrobiosis Associated with Methotrexate Use in a Patient with Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a systemic autoimmune condition prevalent in North America and Northern European populations with an incidence of 1%…
6
Mins
17 Sep 2020
Sjögren’s Syndrome Complicated with Type 2 Autoimmune Hepatitis: A Case Report-Based Review of the Literature
Autoimmune hepatitis is a condition closely related to autoimmune diseases. Previously, it was known to have three distinct types, which were recently…
6
Mins
26 Aug 2020
Virtual or Face-to-Face in the Post COVID-19 World?
Niccolo Machiavelli and Winston Churchill have both been credited with the advice: “Never waste the opportunity offered by a good crisis.” It would be…
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