Articles

Depression, also known as major depressive disorder (MDD), is marked by a loss of interest or pleasure in activities and persistent…

Sex differences in lung diseases represent a critical yet historically overlooked dimension in pulmonary research and clinical care…

Spontaneous pneumomediastinum (SPM) refers to the presence of free air in the mediastinum without preceding trauma or iatrogenic cause. It…

The HIV treatment landscape is evolving, ushering in the era of long-acting (LA) antiretroviral therapy (ART) to support the challenges…

A 24-year-old male with no history of immune deficiency, diabetes, or drug allergies presented to the emergency department. He experienced…

Pneumocystis jirovecii pneumonia (PCP) is an opportunistic fungal infection commonly affecting immunocompromised patients, most notably…

Birt–Hogg–Dubé syndrome (BHDS) is a rare autosomal dominant genetic disorder caused by mutations in the FLCN gene, which encodes…

Asthma is a highly prevalent condition, affecting over 250 million people worldwide. Despite widespread recognition and the availability…

I love the huge variety in the specialty, including the balance of inpatient and outpatient work, acute and routine endoscopy procedures…

Type 2 diabetes (T2D) is a chronic metabolic disorder characterised by insulin resistance and impaired insulin secretion, leading to…

Type 1 diabetes (T1D) is a chronic autoimmune disease that results from the destruction of insulin-producing β-cells in the pancreas…

Eruptive xanthoma is considered a rare disease with an incidence of 18 out of 100,000. It can only be seen in 10% of patients with…

Skin photosensitivity is defined as the cutaneous response to UV radiation (UVR) and/or visible light (VL). The Fitzpatrick Skin Phototype…

Diabetes is a chronic disease characterised by the body’s inability to use or produce sufficient insulin effectively. It is a growing…

Atopic dermatitis (AD) is a common and chronic skin condition that can be significantly impacted by the physiological and immunological…

Nail psoriasis remains a therapeutic challenge that is insufficiently addressed compared to skin and joint involvement. Treatment choices…

Cutaneous lupus erythematosus (CLE) encompasses a group of autoimmune skin disorders that may occur independently or in association with…

Nail lichen planus (NLP) is a chronic inflammatory disorder that can lead to irreversible damage, such as pterygium and anonychia. While…

Tetralogy of Fallot (TOF) is one of the most common forms of cyanotic congenital heart disease, characterised by…

Psoriasis, a prevalent chronic  inflammatory skin disease affecting 2–3% of the global population,1 poses a significant therapeutic…

In August 2025, EMJ conducted individual interviews with two European medical experts and a patient advocate who…

For me, there are two main takeaways from the study. The first is that we still don’t take CSU seriously enough. It is a debilitating…

The skin, as the body’s largest organ, serves as a dynamic interface between internal systems and environmental influences. Beyond its…

Discover groundbreaking eczema research with Sara J. Brown, exploring skin organoids, genetics, and future breakthroughs in dermatology…

Heart failure (HF) constitutes a significant disease burden in the USA. Its prevalence has doubled between 1990–2020, showing an increase…

Coronary bifurcation lesions pose a significant challenge in interventional cardiology, accounting for approximately 15–25% of…

 Our aim is to improve treatment adherence and address psychological barriers such as steroid phobia by increasing knowledge and confidence around AD care…

Michelle Michels and Perry Elliott discuss the CIRRUS-HCM study of EDG-7500 in hypertrophic cardiomyopathy, highlighting clinical benefits…

Explore how machine learning is revolutionising interstitial lung disease management, enhancing early diagnosis, treatment, and prognosis, especially for idiopathic pulmonary fibrosis.

I think what we have discovered post-COVID-19 is that cardiology is a team sport and caring for today’s patient population…

Menopause is a natural biological transition in a woman’s life, marking the permanent cessation of menstruation, and…

What first drew me to cardiology, and then to heart failure, was the ability to treat people and make them feel better…

Renal artery stenosis (RAS), which is most often atherosclerotic in aetiology (90% of cases), remains a contentious indication for…

Spacers or valved holding chambers added to pressurised metered dose inhalers (pMDI) reduce errors in inhaler technique and improve…

We are entering an era of precision healthcare, where genomics and other -omic tests, which are measures of your RNA, proteins…

Acne vulgaris, commonly known as acne, is a skin disease caused by the blockage of hair follicles, high keratin and sebum production in…

Prostate cancer remains one of the most prevalent malignancies among men worldwide, underscoring the need for effective diagnostic…

Psoriasis affects 60 million people globally. It is an inflammatory skin condition that can significantly impact quality of life…

Leiomyosarcoma (LMS) is a malignant neoplasm characterised by smooth muscle differentiation. It is the second most common sarcoma to…

Up to a quarter of patients with classical Hodgkin’s lymphoma (HL) are resistant or have disease relapse after first-line chemotherapy…

Sepsis continues to be a significant contributor to maternal mortality, and is responsible for approximately 11% of maternal deaths…

The technology that I use most frequently is coronary flow reserve combined with PET perfusion imaging and coronary artery calcium scoring…

I began research on cardiovascular magnetic resonance (CMR) with Reichek as one of my two main mentors, and the rest is history.

This article has now been retracted and a retraction statement has been published.

You initially trained as a doctor, specialising in adult medicine, before transitioning to clinical genetics…

Now, for those who don’t know, 10–15% of babies go into the NICU when they’re born, and sometimes it’s because the baby was born…

Epilepsy affects around 50 million people worldwide. Approximately 30% of them experience drug-resistant epilepsy (DRE), which…

Learn more about the long-term health effects persisting one year after COVID-19 infection, including fatigue, breathlessness…

Kian Fan Chung Professor of Respiratory Medicine and Head of Experimental Studies Medicine, National Heart & Lung Institute, Imperial…

Chronic rhinosinusitis is a chronic inflammatory condition of the paranasal sinuses and nasal cavities, affecting an estimated 2–12%…

I think I am what we call a ‘physician scientist’, someone with a strong clinical background who completed a Doctor of Medicine degree…

Experts provide real-life insights and case examples of managing moderate-to-severe atopic dermatitis, sharing their treatment experience with lebrikizumab.

After obtaining my PhD from the University of Göttingen, Germany, in 1999, I moved to the USA for postdoctoral training…

This article discusses changes in the advanced prostate cancer landscape over the past decade that have induced a paradigm shift in…

Abnormal uterine bleeding (AUB) affects 3–30% of perimenopausal women and 5–10% of those who are postmenopausal. While the aetiology of…

That’s an interesting question. I came to this work in a somewhat roundabout way. During my undergraduate studies, I majored in genetics…

Multiple sclerosis (MS) is a complex, lifelong neurological condition that presents with unpredictable symptoms, progressive disability…

Historically, sex-related differences have been underexplored in neurology. It is important to highlight the distinction between sex and…

Epilepsy is a serious and common neurological condition, characterised by recurring, unprovoked seizures, affecting approximately 25…

Neurosonology is a versatile, non-invasive diagnostic modality for evaluating cerebral circulatory disorders.1 It provides real-time…

For more than 40 years, I have been involved in asthma and COPD research. The clinical management of these diseases has changed…

Talha Munir reviews the recent developments in chronic lymphocytic leukaemia research presented at the 2024 American Society of Hematology…

I actually never wanted to be an obstetrician or gynaecologist. I always wanted to be a physician. I was training in diabetes and…

In this patient-focused interview, EMJ spoke to Jean-Philippe Plançon, a patient with chronic inflammatory demyelinating….

It all began when my mother was diagnosed with Huntington’s disease. At the time, Huntington’s was a rare disease, and it still is by…

Some of the most interesting data are precisely those illustrating the reality of clinical practice of physicians attending patients…

Since research on human gene therapy began, the expectations regarding its potential in treating haemophilia have been high. Haemophilia…

TEST In this feature, the authors critically analyse the European standards for Haemophilia Treatment Centres (HTC), examining their…

Rituximab, a monoclonal anti-CD20 antibody, has proven to be an excellent therapeutic agent for haematological diseases. Low-dose…

von Willebrand disease (VWD) is considered the most common inherited bleeding disorder, even surpassing haemophilia A. Nevertheless, VWD…

Synchronous twin malignancies, defined as the simultaneous occurrence of two distinct primary cancers in the same patient, represent a…

Topiramate is a well-known medication used for migraine and epilepsy. Bleeding is a rare and less documented side-effect of this treatment…

Giant cell arteritis (GCA) is the most frequent primary systemic vasculitis in adults, involving medium-to-large-sized vessels. It occurs…

The electronic consultation (eConsult) is a structured, asynchronous communication tool that facilitates dialogue between primary care…

The prevalence of allergic rhinitis (AR) varies between countries but is increasing globally as urbanisation and climate change increase…

Primary immunodeficiencies (PID) are a heterogeneous group of genetic disorders that render the affected child susceptible to…

EMJ spoke with Christina Dalla, a pioneering researcher in neuropsychopharmacology and expert in sex differences in neuropsychiatric…

This year, the EHA Congress provided us with long-term follow-up of some very interesting study, including the GAIA/CLL13 trial…

EMJ spoke with Lukas Rasulic to explore the latest advances in peripheral nerve repair, the integration of functional neurosurgery, and…

Sarcoidosis is a multisystemic disorder of unknown aetiology, characterised by fibrosis and non-necrotising granuloma deposition…

Patrick Maxwell, Regius Professor of Physic and Head of the School of Clinical Medicine at the University of Cambridge, UK took us through…

Cough is one of the most common reasons for which patients seek medical attention in the outpatient setting. Chronic cough in adults…

In the beginning, when I was very young, I was more interested in acute leukaemia and the suffering of young people. When I got to…

Since 1994, the field of allergy and clinical immunology has undergone a profound transformation, both in terms of scientific understanding…

Transcatheter aortic valve implantation (TAVI) is now an established treatment option for elderly patients with severe aortic…

This case is unique because it documents a rare occurrence of a Type IV stent fracture following percutaneous coronary intervention…

Food allergies affect up to 10% of the population in the USA and have been increasing in prevalence over the last 2–3 decades…

Neurocysticercosis, a parasitic brain infection caused by the larvae of Taenia solium that leads to cysts in the central nervous system…

For this article, EMJ conducted an interview with Ahmed Abdelmoity, Professor and Director, Division of Neurology, Children’s Mercy…

Conventional incubators haven’t changed for a long time; it’s been the same basic idea since the 1980s. A lot of people can recognise them…

Joshua Richter – Associate Professor, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA. What initially…

Paclitaxel stabilises microtubules and arrests the cell cycle at the G2/M phase, leading to cell death,15,16 which thereby suppresses…

With the increasing global prevalence of steatotic liver disease (SLD), there is a growing demand for fast, accurate, and low-cost…

Secondary forms of metabolic dysfunction-associated steatotic liver disease (MASLD) have different pathogeneses, outcomes…

Portal vein thrombus (PVT) is characterised by narrowing or blockage of the portal vein by a blood clot. Obstruction may be complete…

Acne is a chronic inflammatory skin disease whose visible effects can have a significant psychological impact on patients. A multimodal…

Inhalation therapy is central to the treatment of patients with COPD, a condition that affects an estimated 480 million people;…

In the context of increasing healthcare complexity and chronic disease prevalence, patient engagement is gaining recognition as a key…

Kidney stones are the most common condition affecting the urinary system, impacting approximately 8–12% of the global population…

Diabetes is a chronic metabolic disorder characterised by persistently high blood sugar levels (hyperglycaemia) caused by deficiencies…

Cases involving co-infections with Mycoplasma pneumoniae and varicella-zoster virus (VZV) are exceedingly rare in medical literature…

The Actinomyces family includes 47 different species. Actinomycosis infections are characterised by abscess formation, granulation…

Bacterial peritonitis can either arise spontaneously or occur secondary to abscesses or perforations in the abdominal cavity. Both…

Overcoming Resistance: How Targeted Approaches Are Changing Management of Advanced EGFR-Mutant Lung Cancer and Pavingthe Way for Precision…

Angioedema (AE) syndromes are associated with recurrent, unpredictable attacks of subcutaneous and submucosal tissue swelling, which can…

Transforming the Cath Lab: Interview with Arnold Seto Division of Cardiology, Long Beach Veterans Administration Healthcare System…

Lifestyle medicine is a large topic area to cover, but there have been some notable advancements in the areas in which I work that are…

Despite advances in first-line endocrine therapy (ET) plus cyclin-dependent 4/6 kinase inhibitors (CDK4/6i) in oestrogen receptor-positive…

Hereditary angioedema (HAE) attacks can be debilitating and potentially life-threatening, particularly when they affect the…

The landscape of neurology biomarkers has evolved significantly in recent years, affording new clinical insights that are helping to…

EMJ spoke with Srihari S. Naidu, who shared insights into his pioneering work in alcohol septal ablation, his contributions as a published…

Invasive Candida infections represent a significant healthcare concern, particularly in the vulnerable paediatric population. Candida…

The Burkholderia cepacia complex (BCC) is a group of at least 20 distinct bacterial species within the Burkholderia genus, including…

Infective endocarditis (IE) often presents in an unusual and vague manner, especially in its early stages, where symptoms can be…

I’m a clinical academic, which is quite a rare breed of doctor, because what I’m doing, along with other clinical academics, is being…

Primary biliary cholangitis (PBC) is characterised by the presence of disease-specific autoantibodies and persistently elevated liver…

Generalised myasthenia gravis (gMG) is a rare and chronic IgG-mediated autoimmune neuromuscular disease that causes fluctuating and…

Heart failure is responsible not only for high morbidity and mortality, but also for significant out-of-pocket expenses for patients…

Systemic lupus erythematosus (SLE) is a complex autoimmune disease that remains challenging to diagnose and treat. In this interview…

Leading neurologist discusses evidence from a real-world post hoc analysis of the PERMIT study supporting perampanel as early add-on…

Both my parents were in the preventive health field; both were integrated providers, chiropractors, and acupuncturists. My dad has a…

Dirk Schnappinger – Professor of Microbiology and Immunology, Weill Cornell Medical College, New York City, USA – Your lab has developed…

David Katz | Chief Medical Officer, Tangelo, Intend; Founder/CEO, DietID, Detroit, Michigan, USA. What initially sparked your interest in…

This study provides a timely examination of antibiotic prescribing practices in the emergency department, a critical frontline in the…

The UK Health Security Agency (UKHSA) is an executive government agency, sponsored by the Department of Health and Social…

Peter Openshaw | Proconsul, Professor of Experimental Medicine, National Heart & Lung Institute – Faculty of Medicine, Imperial…

Percutaneous drainage catheter (PDC) insertion is an effective, safe, and well-tolerated method of relieving obstructions and drainage…

Urolithiasis is a highly prevalent and multifactorial disease, representing the most common urological condition globally. Its incidence…

Pain, increased bleeding, nerve damage, and, at worst, bladder rupture are a few of the potential consequences of undertreated post-partum…

AI has rapidly emerged as a transformative force in various fields, including healthcare. In the realm of medical imaging, AI-powered…

Microwave ablation is an effective treatment modality for T1a and selected T1b renal cell carcinoma (RCC). Independent of the type of…

Endometrial cancer is one of the most common gynaecological cancers in high-income countries and, for many years, has been associated…

EMJ is delighted to introduce Nicholas Fuggle, Associate Professor in Rheumatology at the University of Southampton, UK, and co-organiser…

Leydig cell tumours (LCT) are rare sex-cord gonadal tumours that account for less than 5% of testicular neoplasms. They are often…

Rabies is one of the oldest communicable diseases known to humans and is almost always fatal, with very few cases of survival…

Existing studies reveal alarming levels of AMR in Afghanistan, driven by factors such as self-medication, overuse of antibiotics, and inadequate awareness…

Splenic abnormalities usually present as a focal lesion(s) or diffuse splenomegaly outside the context of trauma. Most splenic lesions are…

Altered gut microbiome profiles correlate with anxiety and depression in humans, and work in animal models has identified specific…

The human body is a holistic system, interconnected by the circulatory, nervous, lymphatic, endocrine, and immune systems that facilitate…

The upper gastrointestinal microbiome, a complex ecosystem of microorganisms that have historically been difficult to identify, may play a…

Multifocal motor neuropathy (MMN) is a rare immune-mediated disorder characterised by progressive, asymmetric muscle weakness…

An acute necrotising myopathy is a distinct form of uncommon muscle disease characterised by the rapid advancement of weakness affecting…

Peritoneal tuberculosis (TB) is a form of extrapulmonary TB that primarily affects areas such as the omentum, liver…

The number one unmet need is that we don’t have a good handle on who’s at risk, because patients generally don’t have too many symptoms

My background is in technical medicine, where I learned some programming but also spent several years in the clinic, shadowing doctors…

Recurrent meningitis is a rare but serious condition, occurring in about 5% of cases of community-acquired meningitis. Recurrent episode…

The possibility of ending the HIV epidemic in Europe is more tangible than ever, but the actions we take now will determine whether we go…

Sarcomatous transformation of the angiomyolipoma (AML) is a rare event with a handful of cases reported in the literature.¹ It is marked by…

What initially drew you to the field of allergy and immunology, and how did your focus come to centre on food allergic disorders? I got…

A recent randomised controlled trial came to the surprising conclusion that dual gonococcal treatment with azithromycin/ceftriaxone…

Following an admission to the authors’ centre with severe anaemia, duodenal biopsy confirmed the diagnosis of Whipple’s disease…

EMJ is pleased to welcome Marcus Drake, Professor of Neurological Urology at Imperial College London, UK, who shared insights into the…

We discovered NDM-1, which stands for New Delhi metallo-beta-lactamase, at the end of 2009, but nobody cared about it too much at the time…

More than 50% of patients with systemic lupus erythematosus (SLE) develop lupus nephritis (LN) during the disease, which may manifest with…

Cervical cancer begins in the epithelial cells of the cervix following an ongoing period of infection with high-risk types of human…

Glomus tumours are uncommon, benign neoplasms originating from the glomus body, predominantly affecting adults between 20–40 years of age…

There is a growing need for personalised medicine to manage and prevent diseases, as well as to monitor patient health continuously, even…

It takes an interdisciplinary approach to solve complex problems in the microbiome because you couldn’t ask for a more complex system.

EMJ is thrilled to present an interview with Massimo Colombo, Past Professor of Gastroenterology at the University of Milan, Italy, that…

There have been great advances in the field of generalised myasthenia gravis (gMG) in recent years, but many patients remain dissatisfied…

Medical and public health professionals are acutely aware of the significant public health concerns posed by adverse events (AE) during…

Our key discoveries range from epidemiologic evidence on breastfeeding and chronic disease prevention to mechanistic research on breast milk compounds and the infant microbiome.

Regenerative medicine has significantly impacted orthopaedic surgery by introducing biological therapies aimed at repairing, restoring, or…

Preterm premature rupture of the membranes (PPROM) impacts 5–7% of all pregnancies. A pregnancy is considered previable, the fetus having…

Plasmacytoid dendritic cells (pDC) primarily function as weak antigen-presenting cells (APC), but have also been shown to express…

David Resühr is transforming medical education with innovation. He is the brain behind several inventions, such as a DIY Ultrasound…

Whole-body magnetic resonance imaging (WB-MRI) has significantly improved oncological disease management by enabling comprehensive…

According to the WHO, the proportion of the world’s population aged over 60 years will almost double, from 12% to 22%, between 2015–2050…

EMJ is delighted to introduce Axel Heidenreich, Professor and Director at the University of Cologne, Germany, who spoke to us about…

Capsule endoscopy was truly a disruptive technology that I had the opportunity to get involved with early on. Disruptive technologies do not come along very often…

Smoking is a major risk factor for cardiovascular disease (CVD) and responsible for around 25% of all CVD-related deaths worldwide…

Sarcoidosis is a disorder that affects multiple systems with unclear causes and is relatively rare. The defining characteristic of this…

Fertility rates have reached the lowest level in recent years all over the world, even in traditionally overpopulated nations such as…

The editor’s pick for this issue is a review article discussing the promise of hyperpolarised xenon MRI, a non-invasive imaging technique…

Type 2 inflammation is involved in severe asthma (SA), chronic rhinosinusitis with nasal polyps (CRSwNP), and eosinophilic granulomatosis…

Endometriosis is defined as the presence of endometrial glands and stroma outside the uterine cavity, which commonly presents with…

Tuberculosis (TB) represents a significant global public health issue, ranking as the 13th leading cause of mortality and standing as the…

Radiographic axial spondyloarthritis (r-axSpA), formerly known as ankylosing spondylitis (AS), is a chronic inflammatory disease that…

Human papillomavirus (HPV) is a sexually transmitted infection linked to genital, anal, and oral warts, as well as cervical and other…

Tuberculosis (TB) is caused by the bacteria Mycobacterium tuberculosis, a complex, rod-shaped, non-spore-forming, thin, aerobic bacterium…

The uncus is a hook-shaped structure located on the most anteromedial aspect of the parahippocampal gyrus, which is part of the medial…

Leiomyomas or fibroids are the most frequently encountered benign neoplasm of smooth muscle origin in women of reproductive age…

Non-steroidal anti-inflammatory drugs (NSAID) are useful in treating musculoskeletal disorders, headaches, pain, fever, and others…

Selective angioembolisation is a common treatment modality for lower gastrointestinal bleeding. Sepsis is an uncommon complication of the…

The authors report a case of delayed transurethral resection of prostate (TURP) syndrome. A 60-year-old man was diagnosed with obstructive…

Intercellular communication, whether through direct cell–cell interactions or the transfer of secreted chemicals, is critical for the…

Chlamydiosis is one of the most prevalent sexually transmitted illnesses globally caused by the bacteria Chlamydia trachomatis…

The thing about paediatric radiology is you cover all different systems. You’ll be doing the musculoskeletal system, the gastrointestinal system…

Colorectal cancer (CRC) is the third most common cancer worldwide, accounting for 10% of all cancer deaths in the UK during the period…

Looking back to the year 2000, we were very divided across the world in understanding PCOS. The Americans had a different definition from…

I really believe that precision medicine has become a reality. This means that you’ll soon be able to visit a normal doctor and have your…

​​Marco Rocha, Thomas Dirschka, and Alison Layton discuss the current acne landscape, the potential role of the skin microbiome in acne…

Androgenetic alopecia (AGA) is the leading cause of hair loss in both men and women. Experts outline current and emerging therapies in the…

To discuss how biologics have disrupted clinical management of atopic dermatitis, and how tralokinumab fits into this paradigm, the EMJ sat…

Hair loss is a common problem in clinical dermatology, with many aetiologies including but not limited to androgenetic alopecia…

Hyaluronan, or hyaluronic acid (HA), is an extracellular matrix glycosaminoglycan distributed throughout the body, primarily found in…

Congenital ichthyosis represents keratinisation disorders characterised by abnormal skin scaling across the entire body, leading to a red…

Basal cell carcinoma (BCC) is a heterogeneous malignant neoplasm and can cause great morbidity as most occur in highly visible areas of…

SLE is a chronic and complex heterogeneous autoimmune disease in which the immune system dysfunctions and inappropriately attacks healthy…

Cancer is on course to be the leading cause of death in the EU by 2035. Europe’s population is ageing rapidly, and obesity rates continue…

Glioblastoma multiforme (GBM), central nervous system (CNS) WHO Grade 4 astrocytoma, is an almost uniformly lethal disease…

Breast cancer is the most common cancer worldwide, accounting for 12.5% of all new cancer cases per year.1 According to the Spanish…

Ovarian cancer is a serious type of cancer that affects women. It has high morbidity and mortality and is the seventh biggest cause of…

In modern oncology, the utilisation of gene expression assays has driven the development of personalised treatment strategies for patients…

Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive sarcoma that most commonly occurs on the trunk of patients…

Pseudomyogenic hemangioendothelioma (PMH) is an uncommon vascular tumour with challenges often in its diagnosis and treatment…

Succinate dehydrogenase (SDH) is a mitochondrial enzyme with a role in both the Krebs cycle and the electron transport chain…

The main findings of the paper revealed that Black patients were underrepresented in clinical trials, particularly with respect to the newer diabetes therapies, sodium-glucose cotransporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists.

Gestational diabetes mellitus (GDM) is a pervasive metabolic disorder associated with a spectrum of long-term adverse outcomes. Recent…

Diabetes is known to be a risk factor for active pulmonary tuberculosis (TB) and the reactivation of latent or previous TB. It is also…

Now, as a practicing physician, I have no insecurities about being a woman in business, because in my training, I would be in a room with hundreds of women at the Women’s Dermatological Society.

The treatment landscape for potentially surgically resectable Stage IIIA non-small cell lung cancer (NSCLC), particularly for…

The demand for highly skilled respiratory clinicians grows as respiratory care becomes increasingly complex with rapid advancement…

Papillary thyroid cancer (PTC) is the most common form of thyroid cancer, accounting for 80–85% of thyroid cancer cases…

The emerging class of agents targeting factor XI/XIa offers the paradigm-shifting possibility of ‘haemostasis-sparing anticoagulation’…

Hypertrophic cardiomyopathy (HCM) is an inherited disorder that may cause disabling and potentially life-threatening symptoms related to…

Sara Tolaney – I started having an interest in medicine from a young age. Part of what drove my interest was having various family members…

Today, the priority populations to target to prevent diabetes should be young adults who have inadequate diets. This information should guide public health action to prevent diabetes.

This case report presents an unusual clinical scenario where a patient experienced temporary paralysis of his lower limbs while driving…

COVID-19 vaccines recommended by the Centers for Disease Control and Prevention (CDC): two mRNA vaccines and a protein-based vaccine…

The number of transcatheter aortic valve replacements/implantations (TAVR/TAVI) has nearly equalled that of the number of surgical aortic…

The authors report the first case of oesophageal cytomegalovirus (CMV) and herpes simplex virus (HSV) co-infection in an immunocompetent…

Improve your awareness and management of patients with osteoarthritis using this interactive case study on a patient experiencing related symptoms

Coarctation of the aorta is a congenital disease involving the cardiovascular system. The presentation can range from being asymptomatic…

Progressive familial intrahepatic cholestasis (PFIC) is a cholestatic condition that typically arises in childhood. As such, if an adult…

Before I decided to pursue a career in pulmonary medicine, I did internal medicine, and was really fascinated by dyspnoea (difficulty…

I believe the real cure lies in catching IBD even earlier than early, meaning, before the first symptoms appear. This concept, which was originally seen with a lot of scepticism, is now gaining momentum…

Cardiovascular disease is still the leading cause of death in patients on haemodialysis (HD).1 Cardiac valve calcification (CVC)…

Left ventricular myocardial crypts are rare structural abnormalities and are defined as invaginations traversing major than a half of the…

I decided to be an oncologist when I was in medical school, mainly because of the inspiring oncologists I met in training and also my…

Meningitis is a rare and unpredictable disease globally, with a high case fatality rate, causing an estimated 250,000 deaths in 2019…

Asthma and chronic obstructive pulmonary disease (COPD) affect more than 550 million people worldwide and are associated with substantial…

With osteoarthritis prevalence rising globally, this interactive case study was designed to highlight the patient journey of a someone with early-stage knee osteoarthritis

Hyperpigmentation disorders, a group of common skin conditions characterised by darkened patches due to excess melanin production, affect…

Osteoarthritis (OA) is the most common arthritis worldwide, causing pain, disability, and loss of function due to chronic joint disease​​…

Gadolinium is an invaluable contrast agent in MRI that has various important benefits in radiology. Its unique magnetic properties allow…

COVID-19 is a novel β-coronavirus caused by infection with SARS-CoV-2. It is the third zoonotic disease caused by coronavirus to affect…

The worldwide prevalence of benign prostatic hyperplasia (BPH) varies between 20–60% in men over 50 years. Similarly, about 50% of men…

A brain tumour develops as a result of abnormal cell growth in the brain. Tumours are classified as malignant or benign. Malignant tumours…

Obstructive sleep apnoea (OSA) is a complex and chronic disease characterised by loud snoring, daytime sleepiness, and witnessed breathing…

Gynaecomastia, the clinical term for the enlargement of the male breast, is characterised by the histological finding of…

Tuberculosis is a well-known endemic disease in India; however, extra-pulmonary tuberculosis in the form of single parotid gland…

The prevalence of both major depressive disorder and cardiovascular disease (CVD) is higher among persons living with HIV (PWH)…

Vasculogenic female sexual dysfunction syndromes affect millions of ageing women worldwide, whose day-to-day symptoms of coital…

Developmental and epileptic encephalopathy (DEE) refers to a collection of rare and severe epilepsies that feature both seizures and…

This study investigates the impact of extracapillary proliferation in proliferative lupus nephritis on remission rates in patients.

I have worked previously in healthcare management consulting, health services research, clinical practice, and healthcare administration…

A 21-year-old female with a history of Type 1 diabetes mellitus (T1DM) with baseline HbA1c ranging from 8.8–12.5%, delayed menarche…

The healthcare industry is known for its demanding and stressful working conditions. The complex link between job-related stressors…

Caudal regression syndrome (CRS) is a group of defects with premature development of the terminal vertebral column, with an incidence of…

Cardiogenic shock continues to carry a high mortality rate despite contemporary care, with no breakthrough therapies shown to improve…

AIHA is an acquired, heterogeneous group of rare diseases with a prevalence of 17 per 100,000.1 This group includes wAIHA…

For clinical applications of AI, it’s still early; most are unlikely to be found at the patient’s bedside and are still in the research…

Parkinson’s disease (PD) is the second-most common neurodegenerative disease after Alzheimer’s disease (AD), with an estimated…

Individuals with neuromuscular diseases (NMD), where deterioration in bulbar function coexists with respiratory muscle weakness, are at…

The occurrence of intramedullary spinal cord abscesses (ISCA) is rare, a phenomenon attributable to a confluence of physiological and…

Fever is a common medical issue encountered in neurorehabilitation units. The most common cause of fever is infection; the common…

Scalp hair is often regarded as a symbol of beauty and vitality across many cultures. Consequently, the loss of hair can significantly…

A previously healthy 17-year-old male was transferred from a community hospital to the authors’ tertiary paediatric emergency department…

One of the wonderful opportunities I’ve had over the years is to interact and go across specialties, divisions, or departments. Here at Mayo Clinic, there’s a wonderful legacy of cross-disciplinary research…

I started off with no particular direction in mind and began training to be a general practitioner (GP). Realising that I needed more…

At the beginning of my research career, I investigated whether electrical stimulation could improve blood flow in the uterine arteries…

I completed my neurology training in Mumbai, India. At the end of my general medical degree, I was influenced by a top-rate neurologist…

When I graduated from Oxford in the early 80s, epidemiology was a key, innovative discipline. There were several important discoveries at…