Allergy & Immunology

During the immunosuppressive phase, researchers identified a marked decline in monocyte function and maturation.

Researchers have discovered a myeloid-derived APC population that is essential for generating both food- and microbiota-specific peripherally induced regulatory T cells.

The study suggests that initiating Artemisia annua SLIT during the pollen season is just as safe and well-tolerated as starting it before.

The results suggest that Wendan Decoction and acupuncture into treatment plans may enhance clinical outcomes for patients with urticaria.

A recent single-blind, randomised controlled trial evaluated the efficacy of normal saline nasal irrigation in managing allergic rhinitis symptoms.

The study found gluten-derived excipients in 44.4% of analgesics and antipyretics.

Over half of the studies identified a direct link between climate change and extended pollen seasons.

The revised mRNA-1010 formulation, evaluated in a subsequent trial, met all primary immunogenicity goals.

The study suggests that chronic inflammation caused by allergic rhinitis could contribute to carcinogenesis through oxidative stress.

Mental health concerns were prevalent, with nearly all families experiencing stress.

This study aimed to assess whether maternal exposure to LC-PCBs in indoor air during pregnancy was associated with the development of asthma.

The study also highlighted a reduction in restricted antibiotic use among patients in the intervention group compared with the control group.

This study explored the hypothesis that mucus transpiration contributes to airway inflammation and chronic respiratory disease.

While food additives play a crucial role in food preservation and enhancement, their potential long-term effects on immune and metabolic health remain a growing concern.

Recent research has identified microRNAs as crucial regulators of inflammation, offering potential new insights into allergic rhinitis pathogenesis.

Beyond antibody transfer through the placenta, breastfeeding may further enhance infant protection.

Discover why new research suggests that early and consistent exposure to food allergens may influence the development of tolerance.

Rocatinlimab, a novel therapy targeting the OX40 pathway, shows potential as an alternative treatment.

Current treatments focus on managing symptoms and include moisturisers, corticosteroids, and calcineurin inhibitors.

Recent studies demonstrate that IL-5 treatment substantially increases type I and III IFN production in mast cells exposed to respiratory viruses.

The Clinical Support Tool is a significant advancement, integrating clear clinical criteria and epinephrine treatment guidelines.

Given that 60% of asthma-related costs are attributed to severe, uncontrolled cases, the need for cost-effective treatment alternatives is crucial.

These findings indicate that omalizumab is a more effective and safer option than multi-allergen OIT for treating multi-food allergy.

Fine dust, a notable seasonal allergen, exacerbates allergic rhinitis symptoms and contributes to respiratory diseases.

Peanut oral immunotherapy using home-measured peanut butter significantly improves long-term desensitisation in children with high-threshold peanut allergy.

A proof-of-concept study was conducted to explore whether dupilumab could induce desensitisation to peanut in children with peanut allergy.

These findings suggest that vonoprazan and tetracycline dual therapy is both effective and well-tolerated, offering a valuable alternative.

These findings suggest that a preoperative radiation therapy boost can safely induce a short-term increase in stromal tumour-infiltrating lymphocytes.

The ability to pharmacologically degrade fat mass and obesity-associated protein represents a promising avenue for enhancing anti-tumour immunity.

Immune checkpoint inhibitors represent an exciting avenue for managing field cancerisation and reducing the keratinocyte carcinoma burden.

These findings highlight a host-intrinsic mechanism responsible for the failure of PD-L1 blockade in ovarian cancer.

The study highlights the necessity of a third vaccination to detect neutralising activity, particularly against emerging Omicron subvariants.

New research maps immune system changes across the human lifespan, revealing key insights into aging and health.

A recent study investigated the efficacy of peanut oral immunotherapy using home-measured peanut butter compared to strict peanut avoidance in children.

Fractionation techniques can significantly enhance the identification of bioactive peptides and immune-related proteins in camel and cow milk.

The findings indicate that preschool wheeze has a profound impact on families, creating high levels of worry and restricting parents’ ability to work and travel.

Targeting RELMβ may provide new therapeutic strategies to prevent severe allergic reactions and improve patient outcomes.

The newly recommended immunotherapy works by gradually increasing the body’s resistance to house dust mites.

New research finds that a mother’s allergic disease and the season of her infant’s birth significantly influence the composition of the breast milk microbiome.

New data from the COVAIL trial highlight the importance of neutralizing antibody titers in reducing COVID-19 risk after mRNA boosters, with stronger protection observed in individuals with prior SARS-CoV-2 infection.

This study highlights the potential of probiotics as an adjunct treatment for allergic rhinitis, offering symptom relief and improving quality of life.

Hydrolysed rice formulas offer unique advantages, such as accommodating cultural, religious, and economic preferences.

Specialist allergy care cuts asthma emergencies in Medicaid-enrolled children, improving outcomes and reducing healthcare visits.

By leveraging the immune-activating properties of epithelial cells, this study highlights the transformative potential of Th2 immunity in early cancer intervention.

A recent study explored a baked milk oral immunotherapy protocol for children with severe cow’s milk allergy.

These findings show the potential of nasal transcriptomic profiling to classify asthma into endotypes, which could inform tailored therapeutic approaches.

Atopic dermatitis, an allergic skin condition characterised by inflammation and heightened IgE levels, is often worsened by psychological stress.

EPIT shows promise in desensitising food allergy patients, but raises concerns about increased adverse events.

Food allergen exclusion increases psychosocial stress in families. Clinician support could improve food allergy management and well-being.

Trigger-specific patterns in anaphylaxis improve diagnosis and treatment, reducing delays in life-saving emergency care.

Multimodal therapy demonstrates superior efficacy in managing allergic rhinitis.

This study highlights that both the 2-dose and 3-dose HepB-CpG regimens provide better seroprotection compared to the 3-dose HepB-alum regimen.

These findings provide new insights into how circadian rhythms, through mitochondrial regulation, contribute to inflammatory responses.

Results showed that ending universal testing and masking correlated with a notable increase in hospital-onset respiratory viral infections compared to community-onset cases.

These findings provide insights into COVID-19’s underlying mechanisms, suggesting targets for interventions that could mitigate severe disease outcomes.

Elevated total immunoglobulin E levels are associated with atopic dermatitis, but IgE levels cannot reliably evaluate AD severity.