Cardiology

Infective endocarditis (IE) often presents in an unusual and vague manner, especially in its early stages, where symptoms can be…

Heart failure is responsible not only for high morbidity and mortality, but also for significant out-of-pocket expenses for patients…

An acute necrotising myopathy is a distinct form of uncommon muscle disease characterised by the rapid advancement of weakness affecting…

Smoking is a major risk factor for cardiovascular disease (CVD) and responsible for around 25% of all CVD-related deaths worldwide…

The emerging class of agents targeting factor XI/XIa offers the paradigm-shifting possibility of ‘haemostasis-sparing anticoagulation’…

Hypertrophic cardiomyopathy (HCM) is an inherited disorder that may cause disabling and potentially life-threatening symptoms related to…

The number of transcatheter aortic valve replacements/implantations (TAVR/TAVI) has nearly equalled that of the number of surgical aortic…

Coarctation of the aorta is a congenital disease involving the cardiovascular system. The presentation can range from being asymptomatic…

Cardiovascular disease is still the leading cause of death in patients on haemodialysis (HD).1 Cardiac valve calcification (CVC)…

Left ventricular myocardial crypts are rare structural abnormalities and are defined as invaginations traversing major than a half of the…

The prevalence of both major depressive disorder and cardiovascular disease (CVD) is higher among persons living with HIV (PWH)…

Vasculogenic female sexual dysfunction syndromes affect millions of ageing women worldwide, whose day-to-day symptoms of coital…

Cardiogenic shock continues to carry a high mortality rate despite contemporary care, with no breakthrough therapies shown to improve…

Children diagnosed with congenital heart disease (CHD) have an increased risk of developing neurodevelopmental disabilities…

Superior vena cava syndrome (SVCS) is a group of clinical manifestations, caused by an obstruction of venous blood flow to the heart…

With over 20 years of experience as a cardiologist, what initially sparked your interest in the field, and continues to motivate you at…

Since its earliest days, the effective use of anticoagulation for prevention of stroke and other thromboembolic events has been limited by…

This review scrutinises the role of guideline-directed medical therapy (GDMT) adherence in some studies and how it influenced…

Little is known about the association between obstructive sleep apnoea (OSA) and vasospastic angina. The authors report the case of a…

Coronary intervention is a therapeutic method for acute coronary syndrome. Characterise patients with acute coronary syndrome treated…

The primary objective was to compare the risk factors and trends of patients with COVID-19 with and without biochemical evidence of…

In the current era of optimal risk factor modification, proprotein convertase subtilisin/kexin type 9 (PCSK9) targeting has emerged as a…

This article was funded by Sanofi and is intended for healthcare professionals.

Fabian Knebel, Sana Klinikum, Berlin, Germany, and Department of Cardiology and Angiology, Charité Campus Mitte, Berlin, Germany, opened the podcast with a definition of hypertrophic cardiomyopathy (HCM), which is characterised by left ventricular hypertrophy. Knebel then described the symptoms of the condition, such as shortness of breath and syncope after physical exertion.

Hannah Gower | Cardiology and Internal Medicine Speciality Registrar, Royal Cornwall Hospitals NHS Trust, UK

Andrew R.J. Mitchell | Consultant Cardiologist at Jersey General Hospital, Saint Helier, Jersey; Honorary Consultant Cardiologist at Oxford University Hospitals NHS Foundation Trust, UK

An estimated 65 million people worldwide have moderate or severe chronic obstructive pulmonary disease (COPD), an umbrella term used to describe a group of progressive lung diseases that obstruct airflow such as emphysema and chronic bronchitis. Smoking contributes to an estimated 90% of COPD cases, as the harmful chemicals produced during tobacco combustion damage the lungs and airways. Although smoking cessation is the only intervention shown to improve COPD prognosis in smokers, many patients who try to quit continue to smoke.

Amyloid light-chain (AL) amyloidosis is a rare systemic disease caused by plasma cell dyscrasia. These plasma cells produce excess Ig light chains, which can misfold, aggregate, and deposit in tissues, resulting in toxicity and organ dysfunction. The heart is among the most commonly affected organs and cardiac involvement is associated with significantly worse outcomes.

Caseous mitral annular calcification (CMAC), sometimes called liquefaction necrosis of mitral annular calcification (MAC), is a rare variant of MAC, a chronic degenerative process that progresses with age.

Obstructive HCM is a condition in which the heart has thickened walls that are not caused by blockage of the heart valves or by very high blood pressure. For the majority of patients, the cause of their disease has a genetic basis and is hereditary. A genetic test can diagnose HCM in some patients, but the results are inconclusive in others.

The harmful effects of cigarette smoke on human health are well documented and supported by evidence from preclinical, clinical, and epidemiological studies. Cigarette smoking damages multiple organs and leads to 8 million global deaths per year from direct use and passive exposure of cigarette smoke to non-smokers.

We are honoured to share our EMJ Cardiology 2022 in review interview with Çetin Erol, Cardiologist at İbn-i Sina Hospital, Faculty of…

Essential hypertension, a significant risk factor for cardiovascular diseases (CVD), kidney failure, and all-cause mortality, is largely reversible with lifestyle changes and highly efficacious medications. However, the prevalence of raised blood pressure (BP) is increasing globally. Considering its lack of symptoms, many people remain undiagnosed and unaware of the risks. In addition, a lack of perceived benefit makes adhering to pharmacological and non-pharmacological interventions challenging for patients.

The aneurysm refers to the increase in arterial diameter in a localised position and this is characterised by the non-parallelism of the arterial wall. Despite prediction models trying to anticipate the onset of an aneurysm, the limits of their accuracy are often reached.

Takotsubo syndrome (TTS), also known as stress-related cardiomyopathy or apical ballooning, is a transient systolic and diastolic dysfunction that is often preceded by some physical or emotional triggers. First described in Japan in 1990, it is derived from a Japanese word meaning ‘octopus pot’.

This article discussed cigarette smoking as a major risk factor for cardiovascular disease (CVD). Looking through the lens of toxic cigarette smoke constituents, the review described the oxidative stress and inflammatory responses induced following their entry into the bloodstream.

Highlighting a presentation that took place as part of the European Society of Cardiology’s (ESC) Heart Failure 2022 congress, this article summarised data on the efficacy and safety of aficamten in patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM).

The imminent need to re-evaluate the standard of care in the 90-day high-risk post-acute myocardial infarction period.