News

Experts have identified two candidate vaccines for Bundibugyo virus, which could take months to get to clinical trial. Instead, they remain focused on affected communities.

Long-term data presented at EuroPCR 2026 showed similar mortality rates after PCI or CABG for left main coronary artery disease.

Systemic lupus erythematosus was associated with lower second delivery rates and recurrent pregnancy complications in a nationwide study.

Combining ixekizumab with tirzepatide improved skin clearance and weight loss in adults with psoriasis and obesity in a Phase 3b trial.

New UKHSA report highlights lower testing uptake, PrEP access, and later diagnoses in Black African communities.

Quantitative MRCP may improve risk prediction and clinical trial development in primary sclerosing cholangitis, an international study suggests.

Neuroimaging use rose across Europe between 2015 and 2022, with CT and MRI volumes increasing more than 40%, alongside marked regional disparities across 29 countries.

Local coronary inflammation was associated with greater risk of adverse cardiovascular events after PCI than systemic inflammation alone.

The WHO Director-General has convened an Emergency Committee regarding the Ebola outbreak in the Democratic Republic of Congo – a public health emergency of international concern.

Researchers discovered that red blood cells mirror endothelial glycocalyx damage, paving the way for blood-based liquid biopsies of vascular health.

Chlorinated drinking water exposure in infancy was associated with increased antimicrobial resistance pathways in the gut microbiome in a new trial.

NHS Modernisation Bill announced abolishing NHS England and reshaping NHS governance alongside wider health reforms.

A new study mapped the brain histamine system, revealing links with cognition, development, and psychiatric disorders.

Pandemic risk is outpacing investments, an expert global monitoring group has warned in a new report launched on 18th May in the margins of the 79th World Health Assembly.

New trial data show dupilumab improves itch, skin healing and quality of life in patients with prurigo nodularis, even without optimal response.

France’s HIV prevention efforts are hindered by low PrEP uptake, especially among women, migrants and younger people despite full health system reimbursement.

A venetoclax-based AML regimen produced high remission rates and prolonged survival in older or unfit patients with newly diagnosed acute myeloid leukaemia.

Metabolomic profiling identified distinct biological asthma subgroups despite similar symptom control and exacerbation histories.

Daraxonrasib demonstrated encouraging survival and tumour response outcomes in advanced pancreatic cancer trials.

Researchers identified persistent drug tolerant cell states in TNBC that survive chemotherapy and may drive metastatic progression and treatment resistance.

Rural HCC incidence increased between 2001 and 2022 while urban rates declined, highlighting widening disparities in liver cancer care.

Percutaneous cryoablation reduced pain and lesion volume in women with umbilical endometriosis in a small single-centre study.

AI-enhanced ECG combined with electronic health records identified individuals at elevated risk of future out-of-hospital cardiac arrest

Early-onset kidney stone disease was linked to higher rates of metabolic and cardiovascular comorbidities in a cohort study of 546 patients.

A gene edited AML transplant strategy achieved rapid engraftment and supported targeted maintenance therapy without prolonged high grade cytopenias in high risk disease.

Slow up-dosing peanut oral immunotherapy helped most preschool children achieve sustained unresponsiveness with few severe reactions.

Researchers identified distinct gut microbiota and metabolomic signatures associated with type 2 diabetes mellitus and coronary atherosclerotic heart disease.

Long-term tofacitinib treatment in juvenile idiopathic arthritis was associated with normal growth and stable hormone biomarkers.

English registry data show lentigo maligna has only a 1% risk of progression to invasive melanoma over 10 years.

Researchers have found that air pollution exposure is associated with lower cognitive performance and signs of vascular brain injury.

Researchers found that matrix assisted laser desorption ionisation imaging combined with machine learning may improve diagnosis and prognostic assessment in rare ampullary cancer.

Researchers validate the Liver Disease Stigma Scale, showing higher stigma in alcohol-associated liver disease compared with non-ALD cases.

CMV screening and antenatal valacyclovir use increased in France after a pivotal 2020 trial, without a rise in pregnancy termination rates.

Orforglipron pills could offer a new option for stabilising weight changes after injectable GLP-1 therapy, according to the ATTAIN-MAINTAIN trial.

The British Secretary of State for Health and Social Care, Wes Streeting, has today resigned. He said today he has “lost confidence” in the Prime Minister’s leadership.

Researchers have found that peripartum depression rates stay elevated across pregnancy and postpartum, with the highest prevalence after delivery.

Short-term testosterone replacement therapy improved sexual and physical function in hypogonadal prostate cancer survivors without biochemical recurrence.

An advanced AI model has outperformed physicians across multiple diagnostic and clinical reasoning tasks, raising implications for future clinical decision-making.

A new study found that IgA nephropathy videos on TikTok and Bilibili varied widely in quality, with important medical information often missing.

AI in cardiology improved workflow efficiency, patient engagement, and mortality outcomes in a major new systematic review.

Researchers have found that IL-17 inhibitors are associated with lower psoriatic arthritis risk after biologic switching in psoriasis.

Tildrakizumab showed sustained efficacy and safety in moderate-to-severe scalp psoriasis, regardless of obesity status, over 52 weeks.

New modelling data suggest that scaling up the global cancer workforce, especially diagnostic and surgical personnel, could substantially reduce cancer mortality worldwide by 2050.

Almost half of the UK’s popular sandwiches qualify for a ‘high’ salt warning, as adults continue to consume an average of 40% above the daily recommended maximum salt intake.

Brain metastases from HCC remain rare, but selected patients receiving local therapy showed markedly longer survival in a retrospective study.

Multi-echo T2* MRI distinguishes neonatal haemochromatosis from other neonatal liver failure causes by detecting thyroid and pancreatic iron deposition.

Long-term LVAD therapy was linked to progressive coagulation changes and hypocoagulability in patients with advanced heart failure.

Polycystic Ovary Syndrome has been renamed Polyendocrine Metabolic Ovarian Syndrome, in a landmark global consensus to deconstruct misunderstanding, backed by 14 years of research.

A novel NK cell activation assay identified early immune activity linked to antibody-mediated rejection after kidney transplantation.

Researchers have called for increased awareness, education, and safe spaces for children in the UK with Type 1 diabetes, following investigation into diabetes technology access.

BCAA supplementation reduced gut inflammation and improved constipation symptoms in a Parkinson’s disease mouse model.

Millions of women quietly live with urological symptoms they believe are inevitable or untreatable, the Urology Care Foundation reported.

ECDC has deployed additional support to the Spanish authorities as passengers and crew continue to disembark the MV Hondius, but maintains that general population risk is low.

Systematic review identified key barriers and facilitators influencing patient acceptance of artificial intelligence in healthcare, highlighting trust, usability, and communication factors.

Longitudinal data showed hydroxyurea adherence declined steadily among patients with sickle cell disease, particularly in older age groups and those with executive difficulties.

AI holds significant promise for improving ovarian care but challenges persist in clinical application, new analysis has found.

Support for AI use increases when it is framed around improving public services, particularly reducing NHS waiting times and bureaucracy, new research from Teneo has found.

Low-dose glucocorticoid treatment caused modest lumbar spine bone loss in rheumatoid arthritis over two years, a meta-analysis finds.

A real-world study found tildrakizumab improved skin clearance, symptoms, and quality of life in adults with plaque psoriasis.

Theta burst stimulation enhanced placebo-driven mood improvement and brain network activity in adults with depressive symptoms.

Deep learning models accurately predicted key DCIS biomarkers from pathology slides, supporting active surveillance strategies.

Plasmodium vivax malaria found in Duffy-negative individuals in Sudan, challenging assumptions about resistance and revealing parasite adaptation. Read more.

Targeting PELI1 in chronic myeloid leukaemia may overcome treatment resistance and eliminate leukaemia stem cells, offering a promising new therapeutic strategy.

A new study explores how mast cell activation and IgE function could improve diagnosis of baked and loosely cooked egg allergy in children.

One colonoscopy can significantly reduce colorectal cancer incidence but not mortality, according to an ongoing long-term randomised controlled trial.

A novel MRI workflow enables non invasive tumour microenvironment assessment, improving biomarker discovery and achieving strong accuracy in breast cancer validation studies.

Tacrolimus was linked to lower mortality and rejection after liver transplantation, but carried a higher risk of diabetes.

The PRECISE score may help clinicians identify MRI changes associated with biopsy progression during prostate cancer active surveillance.

Moderate time-restricted eating patterns were associated with healthier organ ageing markers and improved cardiovascular health in adults with obesity.

Immunotherapy before standard surgery, instead of post-operative chemotherapy, has led to zero relapses after follow-up in new results from the NEOPRISM-CRC trial.

Children surviving acute kidney injury face increased risks of chronic kidney disease and mortality, according to a major meta-analysis.

TP53 multihit alterations show reduced impact in del(5q) myelodysplastic neoplasms, with improved survival and delayed progression to acute myeloid leukaemia.

Children with higher ultra-processed food intake may face a significantly greater risk of developing asthma, according to new prospective research.

Women in England and Wales will no longer face investigations, criminal charges, or custodial sentences for ending their own pregnancy.

Over a median follow-up of 36.4 months, pulse pressure and systolic blood pressure were both associated with cardiovascular death, stroke, and combined outcomes (p

A large BADBIR study assesses serious infection risk across psoriasis systemic treatments, highlighting largely similar safety profiles with some treatment-specific signals.

Researchers found higher rates of postpartum flare in rheumatoid arthritis, compared to stable disease activity in spondyloarthritis patients.

Quantitative ultrasound combined with deep learning predicts three year survival in locally advanced breast cancer before treatment begins.

Insulin resistance is independently linked to MASLD in type 1 diabetes, highlighting a distinct high-risk metabolic phenotype in affected patients.

A study finds TRA vs TFA access routes yield similar radiation exposure during endovascular treatment of intracranial aneurysms.

WHO experts have quashed fears of a hantavirus pandemic, reporting that the outbreak reflects what would be expected.

Researchers have identified sex-specific genetic risk factors in systemic sclerosis, revealing new pathways and potential treatment targets.

3D CT pelvic measurements may predict the difficulty of robot-assisted radical prostatectomy, helping guide surgical planning and improve outcomes.

A portable swab-based test for tuberculosis demonstrated high accuracy and usability across multiple countries, supporting its potential for decentralised diagnosis.

A real-time AI model accurately differentiated benign and malignant gastric ulcers during endoscopy, potentially improving gastric cancer diagnosis.

Semaglutide might offer a novel treatment pathway for alcohol use disorder in those with comorbid obesity. Learn more.

Kidney fibrosis in ageing has been linked to FGFR2 hypermethylation, revealing a potential therapeutic target for chronic kidney disease.

Women in the UK usually endure three or more miscarriages before adequate support, tests, and treatment are provided, Tommy’s report has revealed.

A single, 25 mg dose of psilocybin let to surges in brain entropy and improved psychological wellbeing weeks after intake in a new exploratory study.

High-potency and long-term topical corticosteroid use may increase type 2 diabetes risk, according to a large nationwide cohort study.

A single-dose viral vector-based rabies vaccine shows strong, sustained antibody responses in adults and children with a good safety profile at 1 year.

US model study suggests a targeted hepatitis B birth-dose strategy could increase neonatal infections unless screening and vaccination remain high.

AI and MRI fusion improves brain tumour diagnosis, achieving over 99% accuracy in tumour classification.

Coronary artery disease analysis finds similar mortality between CABG and PCI, but fewer adverse events and repeat procedures with CABG.

WHO has assessed the risk to the global population as low, following an outbreak of hantavirus on a cruise ship crossing the Atlantic Ocean.

Among males, rates of hyperuricaemia increased from 33.7 per 1,000 person-years in non-drinkers to 92.7 in daily drinkers consuming ≥66 g/day.

A new, injectable form of pembrolizumab has been rolled out on the NHS, cutting the time of treatment by up to 90%.

Semaglutide improved motivation in patients with major depressive disorder, holding promise for the treatment of neuropsychiatric disorders characterised by reward dysfunction.

Researchers collated an updated record of male infertility risk factors in a 2026 umbrella review.

In this latest study, researchers showed that while the ketogenic diet maintained intestinal balance under normal conditions, it significantly exacerbated colitis when the gut lining was damaged.

Organ transplant cryopreservation may be influenced by solution properties, with higher glass transition temperatures linked to reduced tissue damage in experimental models.

CRISPR gene therapy shows improved haemoglobin levels and reduced vaso occlusive events in severe sickle cell disease in early phase study data.

COVID-19 disrupted melanoma diagnoses, reducing early detection and shifting prognostic patterns across regions with different public health strategies.

Large phase 3 trial involving over 300 patients with active lupus, those treated with obinutuzumab achieved markedly higher response rates at one year. Nearly 77% of patients receiving the therapy met the primary endpoint

Discover how new findings in endometriosis genetics could transform diagnosis and treatment.

Large cohort study finds increased cognitive impairment risk in rheumatoid arthritis, supporting routine cognitive screening in clinical care.

ADHD symptoms are linked to chronic pain severity, with emotional factors influencing outcomes in patients resistant to standard care.

Australian cohort study has found that HIV incidence among transgender people fell by almost 94% between 2014 and 2023.

Results showed that the POST group achieved a statistically significant reduction in CSMS compared with placebo (p=0.022), with an average improvement 0.6 points greater than control.

Nebuliser use in COPD is most common in severe disease with frequent exacerbations, high symptoms, and reduced lung function.

A deep learning model achieves high accuracy in brain tumour detection from MRI, improving diagnosis and reducing false positives in clinical practice.

Influenza D virus infects human airway cells efficiently and evades early immune responses, raising concerns over zoonotic spillover risk.

MRI Pacinian corpuscles in the forefoot may reflect diabetic sensorimotor polyneuropathy severity, with counts correlating to nerve conduction measures.

A meta-analysis found SGLT2 inhibitors reduced rejection risk after heart transplantation in patients with diabetes, while other major outcomes remained unchanged.

Discover how gut microbiota alterations may drive lupus progression, influence immune responses, and shape treatment outcomes in autoimmune disease.

Bereavement is associated with increased cardiovascular disease risk, with stronger associations observed during the COVID-19 pandemic.

A new conditioning regimen for sickle cell transplantation shows high survival, strong engraftment, and low graft versus host disease in adolescents and adults.

Oral administration of the probiotic led to marked improvements in clinical symptoms, including reduced diarrhoea, improved weight gain, and lower overall allergy scores.

NHS England has set out new maternity care standards aimed at reducing maternal deaths through earlier risk detection, improved specialist access, and strengthened safety monitoring across services.

AI applications in healthcare see significant public support compared with other sectors, experts said at the Health + AI Tech Show.

Narrowband and broadband UVB show similar efficacy in atopic dermatitis, but narrowband therapy is better tolerated, a randomised trial finds.

New findings suggest that body movement may drive brain fluid shifts that help remove neural waste during the day.

Chromosomal instability in oesophageal adenocarcinoma promotes immunosuppression and poor outcomes, revealing new therapeutic targets in tumour immune signalling.

New study shows antibody-based population immunity measures can predict influenza subtype dominance and epidemic size across multiple countries.

HBV reactivation risk increases after rituximab in lymphoma patients once antivirals stop, with most relapses occurring within the first year.

MRI-derived LACI improves sudden cardiac death risk prediction in hypertrophic cardiomyopathy, adding value beyond ESC guideline models.

Indigenous populations historically face a significantly higher prevalence of Type 2 diabetes than global averages, a new systematic review has found.

In this study, researchers analysed 6,805 publications using natural language processing to compare sentiment and language used when discussing psychedelic treatments versus FDA-approved antidepressants.

Advanced age increases cancer-specific mortality in bone-only metastatic prostate cancer, with tumour grade and PSA also key predictors.

A mixed-methods study found telehealth was widely accepted in HIV care, with ongoing concerns about privacy and access.

Amid a mounting workforce crisis, radiologists have highlighted issues with AI implementation in hospitals at the Health + AI Tech Show 2026.

Chronic kidney disease-associated pruritus affects 31% of home haemodialysis patients and is linked to poorer quality of life, a new study reports.

New cohort data show higher air pollution exposure is linked to more respiratory infections and wheezing in infants during the first year of life.

WHO has launched ChatHRP, an AI-assisted tool designed to make reliable information on sexual and reproductive health and rights quickly accessible, for beta-testing.

The findings revealed a significantly higher abundance of an Eubacterium species, with 100% sequence similarity to Eubacterium liposum, in patients with CHD compared with both control and hyperlipidaemia groups.

Behavioural incentives increase daily steps in knee osteoarthritis, but neither incentives nor corticosteroid injections improve symptoms in clinical trial findings.