Gastroenterology

Colorectal cancer (CRC) is one of the most common malignancies in the developed world and with the ‘westernisation’ of diets, other parts of the world…

Prof Gralnek opened the symposium with a clinical case: a 52-year old woman presented with dizziness and explained that she had had bloody stools…

A 54-year-old male with a history of multiple autoimmune arthritides was admitted following a 3-week history of progressive dysphagia with odynophagia…

The inflammatory bowel diseases (IBD) are a group of conditions characterised by chronic, incurable inflammation in the gastrointestinal (GI) tract…

Inflammatory myofibroblastic tumour (IMT) is a rare mesenchymal solid tumour commonly documented in children and young adults, but also found…

IBD is not one disease, but, rather, a whole range of diseases. It is a systemic immune disorder; therefore, in addition to causing conventional…

A paradigm shift has occurred in IBD management, whereby reducing inflammation and mucosal healing has become a the key endpoint that clinicians…

This satellite symposium took place on 7th March 2019, as part of the 14th Congress of the European Crohn’s and Colitis Organisation (ECCO) in Copenhagen…

A highly interactive symposium, including pre-recorded interviews with patients, was chaired by Prof Geert D’Haens. Participation by the audience was…

IBD shows a progressive immunopathogenesis.1 Following an initial immune response, amplification of this inflammatory response leads to the phenotypic…

The epidemiology of diverticular disease (DD) is changing, with an increasing prevalence in younger patients from Europe and the USA, and changing disease…

Despite the fact that the treatment armamentarium for inflammatory bowel diseases (IBD) is growing, unmet medical needs remain…

The objectives of the symposium were to raise awareness of the importance of treating early, setting treatment goals, and using enhanced clinical…

Chemotherapy-induced mucositis is a common, often severe, side effect experienced by cancer patients during their treatment, which is a major challenge…

Colon cancer remains one of the leading causes of cancer-related morbidity and mortality worldwide and it is generally accepted that most colorectal…

The prevalence of non-cardiac chest pain (NCCP) ranges from 13–33%. A majority of those presenting with a chief complaint of chest pain are found to have…

Over the last half century, radiotherapy has been established as a very effective treatment modality for solid tumours. Large numbers of patients…

Infantile colic is a frustrating impasse that affects up to 20% of infants. Even though its pathogenesis is currently unknown, some…

Magnetic resonance cholangiopancreatography (MRCP) is an important diagnostic tool in evaluating patients with biliary laboratory abnormalities after…

Considering patient-reported outcomes (PRO) for optimal disease management is pivotal in many chronic diseases, and inflammatory bowel disease (IBD) is…

This symposium focusses on understanding the advantages and limitations of current management strategies for Crohn’s disease.

Inflammatory bowel disease (IBD) has a dramatic impact on patients and their families, as well as on society as a whole due to its significant economic…

The current treatment strategy for patients with inflammatory bowel disease (IBD) aims to enable physicians to deliver optimal care and to improve the…

Biosimilars have contributed substantially to the evolving therapeutic landscape for inflammatory bowel disease (IBD), enabling healthcare systems to…

Gastric cancer is the second most common cause of cancer-related deaths worldwide, and the 5-year overall survival rate for advanced gastric cancer is ≤25%.

Do flares of ulcerative colitis (UC) cause long-term bowel damage? Dr Sandborn opened the symposium by challenging the audience to think about their…

Given the progressive nature of Crohn’s disease (CD), Prof Panés made a case for timely intervention in at-risk patients to achieve the ultimate goal of…

Recent epidemiological data gathered by the Centers for Disease Control and Prevention (CDC) suggest that colorectal cancer (CRC) is the second leading…

Highlighting the importance of early diagnosis, assessing prognostic factors, and treating to target inflammatory bowel disease.

Abdominal tuberculosis and its protean manifestations still create a diagnostic challenge for clinicians and remain an important concern in the…

Since it was first identified in 1982, Helicobacter pylori has continued to draw attention far beyond its role in peptic ulcer disease and is now…

Fat accumulation in the pancreas, defined as fatty pancreas, is usually an incidental finding during transabdominal ultrasound examination.

Atrophic body gastritis is a chronic disorder characterised by atrophy of the oxyntic glands leading to reduced gastric acid and intrinsic factor secretion.

Biologics are large complex molecules that are produced in living systems. They have revolutionised the treatment of patients suffering from various…

Helicobacter pylori infection is the most prevalent chronic bacterial infection in the world. The prevalence of H. pylori infection ranges from…

Sleeve gastrectomy (SG) has been recognised as an effective procedure for the treatment of morbid obesity and associated comorbidities; however, the shortcomings of SG, such as staple line leak, haemorrhage, vomiting, and weight regain, have also been well-reported. An underestimated adverse effect of SG is nutritional deficiency (ND).

Spasmodic dysphonia (SD): what about it? That is the million-dollar question.

Effective therapy is warranted early in the course of ulcerative colitis, especially for patients judged at a high risk of colectomy.

In the first presentation, Prof Panaccione considered how early treatment of Crohn’s disease (CD) is key for achieving the therapeutic goals, which…

Este seminario especializado financiado mediante una contribución independiente realizada por OM/Vifor Pharma reunió a facultativos especializados en…

The scale of HD is difficult to quantify due to patient misconceptions regarding anal health and poor practice both by physicians and the healthcare…

Clostridium difficile infection (CDI) rates have been increasing, with a corresponding rise of morbidity and mortality. The primary treatment modality of…

Inflammatory bowel diseases (IBDs) are chronic disabling conditions. Despite the benefits of anti-tumour necrosis factor-α agents in improving quality…

Biosimilars follow a rigorous regulatory approval pathway designed to collect and review the totality of evidence from non-clinical analytical…

Patient adherence is a major problem in the treatment of inflammatory bowel disease (IBD). Research has shown that improved patient adherence and…

The objectives of this symposium were to describe the current unmet needs in the treatment and management of inflammatory bowel diseases (IBDs) in…

Proton pump inhibitors (PPI) are one of the most widely prescribed drugs worldwide. They are the mainstay for treatment of most gastric acid-related…

Roux-en-Y gastric bypass (RYGB) surgery is a very successful option for the management of obesity, and our understanding of how this intervention…

In this century, eosinophilic oesophagitis (EoE) has become a more recognised allergic disease, resulting in the publication of two consensus reports…

Eosinophilic oesophagitis (EoE) is an emerging disorder that manifests clinically with characteristic symptoms of oesophageal dysfunction…

Background: Infliximab (IFX) trough levels measurement could partially explain mechanisms of loss in response to this drug.

Barrett’s oesophagus (BO) is one of the most important complications of gastro-oesophageal reflux disease as it may progress to oesophageal adenocarcinoma.

Eosinophilic oesophagitis is an inflammatory condition associated with marked eosinophil accumulation in the mucosal tissues of the oesophagus.

The scope of this short review is to discuss the current state of practice in detection and removal of sessile serrated polyps (SSPs) during…

Summary of Presentations from the ESMO 18th World Congress on Gastrointestinal Cancer held in Barcelona, Spain from 28th June–2nd July 2016

Diabetes is a non-communicable disease (NCD) meaning that it often cannot be seen. After 20 years of living with Type 1 diabetes I am lucky to have no…

Inflammatory bowel disease (IBD) describes two inflammatory conditions of the gastrointestinal tract: ulcerative colitis (UC) and Crohn’s disease (CD)…

Inflammatory bowel disease (IBD) management goals have recently focussed on gastrointestinal symptom resolution and mucosal healing. IBD causes systemic…

CD is a complex disease, which requires effective treatment options to improve the quality of life for patients.

The treatment landscape of ulcerative colitis (UC) is changing, with new treatment options becoming available and insights into disease management…

The American Society of Clinical Oncology’s 2016 Gastrointestinal Cancer Symposium (ASCO-GI), held in San Francisco, California, USA, provided a forum…

Despite major advances in the inflammatory bowel disease (IBD) treatment landscape, the management of ulcerative colitis (UC) and Crohn’s disease (CD)…

This symposium provided an opportunity for global experts to discuss the challenges posed by the introduction of biosimilars. The impact of the…

Ulcerative colitis (UC) carries a significant, progressive disease burden that is often underestimated or misinterpreted by healthcare providers.

The importance of the gut microbiota to health is becoming more widely appreciated. The range of commensal microorganisms in healthy individuals and in…

Pancreatic cystic neoplasms (PCNs) are no longer considered as rare entities because their prevalence in the general population ranges from 3–20%.

Acute diverticulitis is an acute inflammation of colonic diverticulae that is associated with an episode of severe, prolonged, lower abdominal pain…

Helicobacter pylori treatment is becoming a challenge in light of increasing antimicrobial resistance and falling eradication rates. This is a cause for…

Endoscopic retrograde cholangiopancreatography has become an effective and safe therapeutic method, with clinical success of more than 80%

Advances in medical and surgical therapy mean that significant numbers of children with previously fatal liver disease are surviving into adult life.

Hepatitis E virus (HEV) is a single-stranded, non-enveloped, positive-stranded RNA virus that can be classified into four genotypes with distinct…

Proudly supported by The Urology Foundation, Blue September is a fun way of delivering a serious message about ‘facing up to cancer in men’.

There is a new guy on the block. A new guy in the guise of a book written by new-age men talking about their very own personal experiences of their…

Research and development in the 21st century is a rapidly changing landscape. Advances in technology have been the driving force to further advances in…

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that affects up to 15% of the European and North American population…

A wide range of dyspeptic symptoms in clinical practice reflect the high prevalence of functional disorders of the gastrointestinal (GI) tract.

Nasogastric (NG) tubes are commonly used for enteral feeding. Complications of feeding tube misplacement include malnutrition, pulmonary aspiration, and…

Eosinophilic oesophagitis (EoE) is an increasingly prevalent disease in clinical practice. Nowadays it is the most frequent cause of dysphagia in young…

Barrett’s oesophagus (BO) is a precancerous lesion associated with the development of oesophageal adenocarcinoma (OAC). Although different types of…

Acute upper gastrointestinal bleeding (AUGIB) is the most common GI emergency, responsible for up to 70,000 hospital admissions in the UK and…

The small intestinal neoplasia group includes different types of lesions and are a relatively rare event, accounting for only 3-6% of all…

The discovery of Helicobacter pylori was hopeful as this agent was included in the list of ‘preventable- infectious carcinogens’, and many non-treatable…

Complicated diverticular disease refers to patients who present with abscess, peritonitis, bleeding, fistula, or bowel obstruction. Management paradigms…

Summary of Presentations from the Norgine Sponsored Satellite Symposium, UEG Week, Berlin, Germany, 12th–16th October 2013

Irritable bowel syndrome (IBS) is a highly prevalent functional disorder characterised by chronic and recurrent abdominal pain and altered bowel habit.

While irritable bowel syndrome (IBS) is still considered a ‘disorder of gut function’ and is diagnosed on the basis of symptoms, evidence is growing to…

Irritable bowel syndrome (IBS) is a functional bowel disorder by unknown aetiology. Several reviews are written about pharmacological and psychological…

Optical enhancement technologies are emerging as promising tools to improve diagnosis and clinical management of patients with IBD.

Recruitment of circulating leukocytes to areas of inflammation is a key process in the pathophysiology of inflammatory bowel diseases, including…

The excessively widespread use of antibiotics has created many threats. A well-known problem is the increasing bacterial resistance to antibiotics…

Management guidelines offer clinicians clear, evidence-based and often succinct treatment advice. For ulcerative colitis these guidelines describe the…

Hilar cholangiocarcinoma (HCCA) is characterised by late clinical symptoms. As a consequence, most patients will not undergo surgery, and palliation is…

Necrotising pancreatitis can be life-threatening, but the introduction of endoscopic necrosectomy has led to a tremendous reduction of lethality.

The vagus nerve, the major nerve of the parasympathetic nervous system, innervates several organs from the neck to the abdomen. The vagal branches…

Crohn’s disease is a chronic relapsing inflammatory bowel disease that may affect any part of the gastrointestinal tract. The ileum, colon, and perineum…

The risk of digestive cancer in each country is analyzed in cancer registries for Incidence and Mortality. Survival is estimated from registries with a…

Endoscopic detection and evaluation of early neoplasia in the gastrointestinal tract should be carried out by systematic assessment of a standard set…

Acute pancreatitis is the most common disorder of the pancreas. The incidence of the disease has increased markedly during the past decades.

Cholangiocarcinoma (CC) is a tumour with a poor prognosis. The treatment of CC is challenging as the tumour is usually diagnosed late and the treatments…